Synthesis of nucleoside phosphate and phosphonate prodrugs - Test2 - elhamkhani - TriplyDB

Synthesis of nucleoside phosphate and phosphonate prodrugs

Synthesis of nucleoside phosphate and phosphonate prodrugs

http://www.wikidata.org/entity/Q26865400

about

Synthesis and antiviral evaluation of 2′,2′,3′,3′-tetrafluoro nucleoside analogs Synthetic, Functional Thymidine-Derived Polydeoxyribonucleotide Analogues from a Six-Membered Cyclic Phosphoester.ENOblock Does Not Inhibit the Activity of the Glycolytic Enzyme Enolase Alpha-carboxy nucleoside phosphonates as universal nucleoside triphosphate mimics.A multifunctional catalyst that stereoselectively assembles prodrugs.Correction of a genetic deficiency in pantothenate kinase 1 using phosphopantothenate replacement therapy.Bromopyridone Nucleotide Analogues, Anoxic Selective Radiosensitizing Agents That Are Incorporated in DNA by Polymerases.Anti-norovirus therapeutics: a patent review (2010-2015).Synthesis and Anti-HCV Activity of a Novel 2',3'-Dideoxy-2'-α-fluoro-2'-β-C-methyl Guanosine Phosphoramidate Prodrug.Flex-nucleoside analogues - Novel therapeutics against filoviruses.ProTides of BVdU as potential anticancer agents upon efficient intracellular delivery of their activated metabolites Betulin Phosphonates; Synthesis, Structure, and Cytotoxic Activity.Design and Synthesis of Fluorescent Acyclic Nucleoside Phosphonates as Potent Inhibitors of Bacterial Adenylate Cyclases.Synthesis and Biological Evaluation of 9-Deazaadenine 5'-Deoxy-6',6'-Difluoro-Carbocyclic C-Nucleoside Phosphonic Acid Derivatives.Bis(benzoyloxybenzyl)-DiPPro nucleoside diphosphates of anti-HIV active nucleoside analogues.Design, synthesis and antiviral evaluation of 2'-C-methyl branched guanosine pronucleotides: the discovery of IDX184, a potent liver-targeted HCV polymerase inhibitor.A Modular Synthesis of Modified Phosphoanhydrides.Nucleotide Substrate Specificity of Anti-Hepatitis C Virus Nucleoside Analogs for Human Mitochondrial RNA Polymerase.Synthesis, Hydrolysis, and Protonation-Promoted Intramolecular Reductive Breakdown of Potential NRTIs: Stavudine α-P-Borano-γ-P-N-l-tryptophanyltriphosphates.Next-Generation Reduction Sensitive Lipid Conjugates of Tenofovir: Antiviral Activity and Mechanism of Release.Bifunctional aryloxyphosphoramidate prodrugs of 2'-C-Me-uridine: synthesis and anti-HCV activity.Synthesis and antiviral evaluation of fluorinated acyclo-nucleosides and their phosphoramidates.Reduction Sensitive Lipid Conjugates of Tenofovir: Synthesis, Stability, and Antiviral Activity.Synthesis and Antiviral Activity Evaluation of 2',5',5'-Trifluoro-Apiosyl Nucleoside Phosphonic Acid Analogs.Lipophilic prodrugs of nucleoside triphosphates as biochemical probes and potential antivirals Nitrogenous Derivatives of Phosphorus and the Origins of Life: Plausible Prebiotic Phosphorylating Agents in Water.Synthesis and Evaluation of 2,6-Modified Purine 2'-C-Methyl Ribonucleosides as Inhibitors of HCV Replication Anchimerically Activatable Antiviral ProTides.The protecting-group free selective 3'-functionalization of nucleosides Synthesis and antiviral evaluation of 2-amino-6-carbamoylpurine dioxolane nucleoside derivatives and their phosphoramidates prodrugs.Effective encapsulation and biological activity of phosphorylated chemotherapeutics in calcium phosphosilicate nanoparticles for the treatment of pancreatic cancer.Azetidine-derived dinuclear zinc catalyzed asymmetric phospha-Michael addition of dialkyl phosphite to α,β-unsaturated carbonyl compounds.Nucleoside diphosphate and triphosphate prodrugs - An unsolvable task?Synthesis and anti-HCV activity of a series of β-d-2'-deoxy-2'-dibromo nucleosides and their corresponding phosphoramidate prodrugs.Advanced Prodrug Strategies in Nucleoside and Non-Nucleoside Antiviral Agents: A Review of the Recent Five Years.Fluorinated nucleosides as an important class of anticancer and antiviral agents.Prometabolites of 5-Diphospho-myo-inositol Pentakisphosphate.Reprofiling of full-length phosphonated carbocyclic 2'-oxa-3'-aza-nucleosides toward antiproliferative agents: Synthesis, antiproliferative activity, and molecular docking study.Current and future use of nucleo(s)tide prodrugs in the treatment of hepatitis C virus infection.Applying the prodrug strategy to α-phosphonocarboxylate inhibitors of Rab GGTase--synthesis and stability studies.

P2860

Q28595401-FE473C54-9905-4ADF-91A2-DFE8418D0122 Q33746202-20D777DC-5301-4C92-9373-04F55917BA0C Q34548185-60740B19-D63C-44F8-98E2-992B79F0A7C1 Q35212611-80811E9E-FC52-43D4-8BA7-1DE50F32FACE Q36357128-B621858B-B55D-46AA-8936-F03D97D15BFA Q36608623-F128DF81-7465-4BC5-99BF-BAAEF03057F2 Q36928849-483EF10B-C9F6-4B5E-82CF-D3CFFAC794B2 Q37101808-1605FFCF-4F70-4E90-BCFE-B76386D1B7C9 Q38699932-8F1F7681-421D-4FBC-9B21-6E0882DA77DD Q38705163-4953E530-9EB6-4B31-9446-C46CB5CC84CA Q38732666-DB947440-B686-4FDD-8C6D-87B058D12626 Q38749433-563B2369-2F92-49FF-BE41-89CB8C8577CB Q38806723-414190DE-E474-4540-BF42-A5F6AC783F45 Q38827914-64F66518-7E1E-4308-916C-63AF1C62EB25 Q38890254-3CCC797B-517B-4101-9628-D8DC25494E8B Q38958064-F283FBFF-2AB1-4D9B-8C0D-0C61399CB78E Q39000656-CD5E37AA-7D00-4E06-9213-2838B113C4CE Q40180055-903D37E9-9E1C-43B7-918C-12905EAD263D Q40335490-A5AEA7ED-CEC7-4810-B585-E70A03883B9B Q40433318-5B6E386C-3256-43A7-B3EE-AD92AF865B00 Q40514370-65AE4780-0911-46DC-94E1-04ED0B2A8C60 Q40530991-AF465688-1C5F-4294-B9FD-16D09DADCF0C Q40654775-BE714E86-A0D3-4799-B440-9DEBE40442CF Q40923210-F3722182-FD51-4AD5-AFB2-E19376B2045F Q40936332-CE600DC2-E415-4FDA-A2B5-5D46ACFEF9D6 Q41666525-43FAD911-CE89-4248-8F9E-3B6D5F7084C0 Q41783595-8343AFF9-019A-40FF-A540-85811403D438 Q41930289-09810367-A6EC-4D2A-9D2A-41953ABB5E36 Q41952812-1E0B4334-106C-4EA6-BD96-ECDD84DA3513 Q42178078-34ACBEDF-1A38-47BE-B173-25C54671B546 Q45062589-9CF3FE6F-4A76-4589-81D7-0992F758A018 Q47379280-D5BD9824-D848-4BBD-B226-046177DB7A22 Q47592519-2CE5CE4E-4CD8-4C71-9138-1122ACDB5B89 Q47601762-F9D2E0ED-86AA-43A9-8768-E17B3A322780 Q47611417-225FCD44-872D-4502-8C87-6A87D14A152B Q47637142-AFE01E1D-61B2-417C-ACD6-3036E9F11BB7 Q48158466-615F6F9C-7545-4C74-9F8B-3E64E6B270AF Q48328758-E701E676-783A-418E-BCF6-7C7E02EB2828 Q49797854-43D93E77-7238-4F4E-A245-20F890B3441C Q50971739-4EA3A8BE-CD76-461F-89A4-98C4FB0E4E5E

P2860

Synthesis of nucleoside phosphate and phosphonate prodrugs

http://www.wikidata.org/entity/Q26865400

description

2014 nî lūn-bûn

@nan

2014 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2014 թվականի սեպտեմբերին հրատարակված գիտական հոդված

@hy

2014年の論文

@ja

2014年論文

@yue

2014年論文

@zh-hant

2014年論文

@zh-hk

2014年論文

@zh-mo

2014年論文

@zh-tw

2014年论文

@wuu

name

Synthesis of nucleoside phosphate and phosphonate prodrugs

@ast

Synthesis of nucleoside phosphate and phosphonate prodrugs

@en

Synthesis of nucleoside phosphate and phosphonate prodrugs

@nl

type

label

Synthesis of nucleoside phosphate and phosphonate prodrugs

@ast

Synthesis of nucleoside phosphate and phosphonate prodrugs

@en

Synthesis of nucleoside phosphate and phosphonate prodrugs

@nl

prefLabel

Synthesis of nucleoside phosphate and phosphonate prodrugs

@ast

Synthesis of nucleoside phosphate and phosphonate prodrugs

@en

Synthesis of nucleoside phosphate and phosphonate prodrugs

@nl

P1433

Q26865400-87B31CE0-9DDF-4955-9FD1-3C1E71FD253F

P1476

Q26865400-BD8E728E-64D4-48A6-BBBD-47D0AED2048B

P2093

Q26865400-221F246F-6A5C-4871-9E41-CDE7B5639EA7

Q26865400-28B77966-4ABA-42CE-A150-8108F67B8075

Q26865400-8F9291FC-B7DE-4F20-99F5-9D8B29BE123F

Q26865400-F4DEC231-55DD-495E-BCF7-0F7DD8CF103E

P2860

Q26865400-02B7876C-ECD7-462C-962F-E2D83BFD029A

Q26865400-02E90990-1CA3-422C-B69C-29789C829D90

Q26865400-03EF398D-C876-425F-9178-E5B44E951BAB

Q26865400-04E98BB1-817E-47BB-AA2C-1555D6072EE0

Q26865400-04FB1337-F235-444F-877C-B96138F8C66B

Q26865400-05222EAD-2ECB-4DAD-ACC1-8CB8156F856D

Q26865400-05366C3E-791A-40F7-9F88-3DA652EE9F9F

Q26865400-05AA704D-37D5-4797-A72C-DA1AC160EEDE

Q26865400-077ACD4D-772C-4CE6-B107-77A70B5121E9

Q26865400-0912B430-F767-467C-88B7-47012A68C9DC

P304

Q26865400-A99E7B0C-4D61-4CAE-A59D-82A9DD7463DA

P31

Q26865400-F00286F4-4BA0-4268-B721-D32CCFFDB749

Q26865400-F52C9FBE-F423-472D-897E-2840269DA610

P356

Q26865400-D46413E1-9CF3-42F0-BE92-A7C5A7B71C0F

P407

Q26865400-5A62B84D-EE26-4D2A-8291-C9DDB2C29C6C

P433

Q26865400-8B05AF01-5E08-4171-8056-14F28547B81B

P478

Q26865400-29A47830-46DC-466C-B70B-FB2348AC4188

P50

Q26865400-9C8B145A-673C-4918-863C-38A2511164F3

P577

Q26865400-C971710B-891D-41F6-9951-F3240C41ED47

P5875

Q26865400-DD94365D-DD61-44EA-A9D7-3895A4551C9B

P698

Q26865400-01392DA1-97D2-45C9-A7C3-C5887747846D

P921

Q26865400-0A391EEF-2C3E-416D-B0A0-E724C43DC50C

Q26865400-67CAFD5D-C4FF-486C-B804-446098B2C267

Q26865400-788E5748-9B95-40EA-A624-625059CE9B1F

Q26865400-F6C03DEB-984E-4217-A5EA-B3C60011E1AB

P932

Q26865400-2D4A3245-281C-4329-9B75-4DB90C0D5332

P356

P1433

Chemical Reviews

P1476

Synthesis of nucleoside phosphate and phosphonate prodrugs

@en

P2093

Ethel C. Garnier-Amblard

http://www.w3.org/2001/XMLSchema#string

Franck Amblard

http://www.w3.org/2001/XMLSchema#string

Steven J. Coats

http://www.w3.org/2001/XMLSchema#string

Ugo Pradere

http://www.w3.org/2001/XMLSchema#string

P2860

Novel antiviral C5-substituted pyrimidine acyclic nucleoside phosphonates selected as human thymidylate kinase substrates

Structure of thymidylate kinase reveals the cause behind the limiting step in AZT activation

Phosphorylation of nucleosides and nucleoside analogs by mammalian nucleoside monophosphate kinases

Adefovir dipivoxil for the treatment of hepatitis B e antigen-positive chronic hepatitis B

Membrane-permeable dideoxyuridine 5'-monophosphate analogue inhibits human immunodeficiency virus infection

Greatly enhanced inhibition of human immunodeficiency virus type 1 replication in CEM and HT4-6C cells by 3'-deoxythymidine diphosphate dimyristoylglycerol, a lipid prodrug of 3'-deoxythymidine

Aryl phosphate derivatives of AZT retain activity against HIV1 in cell lines which are resistant to the action of AZT

Synthesis and in vitro evaluation of a phosphonate prodrug: bis(pivaloyloxymethyl) 9-(2-phosphonylmethoxyethyl)adenine

The synthesis, characterization, and preliminary biological evaluation of 1-beta-D-arabinofuranosylcytosine-5'-diphosphate-L-1,2-dipalmitin

Synthesis and anti-HIV evaluation of some phosphoramidate derivatives of AZT: studies on the effect of chain elongation on biological activity

P304

9154-218

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1021/CR5002035

http://www.w3.org/2001/XMLSchema#string

P407

P433

18

http://www.w3.org/2001/XMLSchema#string

P478

114

http://www.w3.org/2001/XMLSchema#string

P50

Raymond F. Schinazi

P577

2014-09-24T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

264989088

http://www.w3.org/2001/XMLSchema#string

P698

25144792

http://www.w3.org/2001/XMLSchema#string

P921

Angliavandeniai

inorganic compound

organophosphorus compound

pharmaceutical preparation

P932

4173794

http://www.w3.org/2001/XMLSchema#string