The role of PARP in DNA repair and its therapeutic exploitation
about
STRUCTURE-FUNCTION OF THE TUMOR SUPPRESSOR BRCA1Failure of iniparib to inhibit poly(ADP-Ribose) polymerase in vitroCurrent and emerging therapies in unresectable and recurrent gastric cancerDNA repair targeted therapy: The past or future of cancer treatment?Variations in telomere maintenance and the role of telomerase inhibition in gastrointestinal cancerHpz1 modulates the G1-S transition in fission yeastCRISPR/Cas9-Mediated Correction of the FANCD1 Gene in Primary Patient CellsHereditary pancreatic cancer: related syndromes and clinical perspective.Poly(ADP-ribose) polymerase inhibitors sensitize cancer cells to death receptor-mediated apoptosis by enhancing death receptor expression.New facets in the regulation of gene expression by ADP-ribosylation and poly(ADP-ribose) polymerases.Niraparib (MK-4827), a novel poly(ADP-Ribose) polymerase inhibitor, radiosensitizes human lung and breast cancer cells.Basal activity of a PARP1-NuA4 complex varies dramatically across cancer cell lines.Genomic scan reveals loci under altitude adaptation in Tibetan and Dahe pigs.Synthetic lethal interactions between EGFR and PARP inhibition in human triple negative breast cancer cellsThe role of Kif4A in doxorubicin-induced apoptosis in breast cancer cells.Rapamycin-resistant poly (ADP-ribose) polymerase-1 overexpression is a potential therapeutic target in lymphangioleiomyomatosis.Proteome-wide analysis of mutant p53 targets in breast cancer identifies new levels of gain-of-function that influence PARP, PCNA, and MCM4.Poly(ADP-ribose) polymerase-13 and RNA regulation in immunity and cancer.p21CDKN1A Regulates the Binding of Poly(ADP-Ribose) Polymerase-1 to DNA Repair Intermediates.Clinical utility of targeted treatments in the management of epithelial ovarian cancer.Krüppel-like factor 8 emerges as an important regulator of cancerAlternative modes of binding of poly(ADP-ribose) polymerase 1 to free DNA and nucleosomesThe Antitumor Activity of Antrodia camphorata in Melanoma Cells: Modulation of Wnt/β-Catenin Signaling Pathways.Dentatin Induces Apoptosis in Prostate Cancer Cells via Bcl-2, Bcl-xL, Survivin Downregulation, Caspase-9, -3/7 Activation, and NF-κB Inhibition.Evaluation of candidate biomarkers to predict cancer cell sensitivity or resistance to PARP-1 inhibitor treatmentOlaparib.Transcriptional profiling reveals elevated Sox2 in DNA polymerase ß null mouse embryonic fibroblasts.Blocking c-Met-mediated PARP1 phosphorylation enhances anti-tumor effects of PARP inhibitors.PARP1 expression, activity and ex vivo sensitivity to the PARP inhibitor, talazoparib (BMN 673), in chronic lymphocytic leukaemia.Crosstalk between poly(ADP-ribose) polymerase and sirtuin enzymes.Regulation of DNA glycosylases and their role in limiting disease.Inhibiting the DNA damage response as a therapeutic manoeuvre in cancer.Strategic Combination of DNA-Damaging Agent and PARP Inhibitor Results in Enhanced CytotoxicityQuantification of cellular poly(ADP-ribosyl)ation by stable isotope dilution mass spectrometry reveals tissue- and drug-dependent stress response dynamicsNew developments in the treatment of ovarian cancer--future perspectives.Inhibition of CDK4/6 protects against radiation-induced intestinal injury in mice.Overview on poly(ADP-ribose) immuno-biomedicine and future prospects.The La antigen is over-expressed in lung cancer and is a selective dead cancer cell target for radioimmunotherapy using the La-specific antibody APOMAB®.Correlation between PARP-1 immunoreactivity and cytomorphological features of parthanatos, a specific cellular death in breast cancer cells.Targeting PARP-1 allosteric regulation offers therapeutic potential against cancer.
P2860
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P2860
The role of PARP in DNA repair and its therapeutic exploitation
description
2011 nî lūn-bûn
@nan
2011 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
The role of PARP in DNA repair and its therapeutic exploitation
@ast
The role of PARP in DNA repair and its therapeutic exploitation
@en
The role of PARP in DNA repair and its therapeutic exploitation
@nl
type
label
The role of PARP in DNA repair and its therapeutic exploitation
@ast
The role of PARP in DNA repair and its therapeutic exploitation
@en
The role of PARP in DNA repair and its therapeutic exploitation
@nl
prefLabel
The role of PARP in DNA repair and its therapeutic exploitation
@ast
The role of PARP in DNA repair and its therapeutic exploitation
@en
The role of PARP in DNA repair and its therapeutic exploitation
@nl
P2860
P356
P1476
The role of PARP in DNA repair and its therapeutic exploitation
@en
P2093
P2860
P2888
P304
P356
10.1038/BJC.2011.382
P407
P577
2011-10-01T00:00:00Z
P5875
P6179
1009307266