Why the stroma matters in breast cancer: insights into breast cancer patient outcomes through the examination of stromal biomarkers - Test2 - elhamkhani - TriplyDB

Why the stroma matters in breast cancer: insights into breast cancer patient outcomes through the examination of stromal biomarkers

Why the stroma matters in breast cancer: insights into breast cancer patient outcomes through the examination of stromal biomarkers

http://www.wikidata.org/entity/Q27023385

about

Tensile Forces Originating from Cancer Spheroids Facilitate Tumor Invasion Breast Cancer Cell Invasion into a Three Dimensional Tumor-Stroma Microenvironment.Stromal characteristics may hold the key to mammographic density: the evidence to date Mammographic density: a potential monitoring biomarker for adjuvant and preventative breast cancer endocrine therapies Progress in the clinical detection of heterogeneity in breast cancer Preferential, enhanced breast cancer cell migration on biomimetic electrospun nanofiber 'cell highways'Intratumoral and peritumoral radiomics for the pretreatment prediction of pathological complete response to neoadjuvant chemotherapy based on breast DCE-MRI.Reorganized Collagen in the Tumor Microenvironment of Gastric Cancer and Its Association with Prognosis.Identification of prognostic collagen signatures and potential therapeutic stromal targets in canine mammary gland carcinoma.Stromal, rather than epithelial cyclooxygenase-2 (COX-2) expression is associated with overall survival of breast cancer patients.Hypoxia and the extracellular matrix: drivers of tumour metastasis Dense collagen-I matrices enhance pro-tumorigenic estrogen-prolactin crosstalk in MCF-7 and T47D breast cancer cells.Dense fibrillar collagen is a potent inducer of invadopodia via a specific signaling network.GAL3ST2 from mammary gland epithelial cells affects differentiation of 3T3-L1 preadipocytes.Type III Collagen Directs Stromal Organization and Limits Metastasis in a Murine Model of Breast Cancer.Identification of stromal ColXα1 and tumor-infiltrating lymphocytes as putative predictive markers of neoadjuvant therapy in estrogen receptor-positive/HER2-positive breast cancer Multiscale modelling of solid tumour growth: the effect of collagen micromechanics.Tumor Cell-Driven Extracellular Matrix Remodeling Drives Haptotaxis during Metastatic Progression.GT198 Expression Defines Mutant Tumor Stroma in Human Breast Cancer.Dense fibrillar collagen is a master activator of invadopodia Local adipocytes enable estrogen-dependent breast cancer growth: Role of leptin and aromatase.Stromal Activation by Tumor Cells: An in Vitro Study in Breast Cancer The independent roles of mechanical, structural and adhesion characteristics of 3D hydrogels on the regulation of cancer invasion and dissemination Cancer-associated fibroblast-secreted CXCL16 attracts monocytes to promote stroma activation in triple-negative breast cancers Microstructural models for diffusion MRI in breast cancer and surrounding stroma: an ex vivo study.Extracellular matrix signatures of human mammary carcinoma identify novel metastasis promoters.Role of pancreatic stellate cells in chemoresistance in pancreatic cancer.Priming cancer cells for drug resistance: role of the fibroblast niche.Imaging the Tumor Microenvironment.Inhibition of discoidin domain receptor 1 reduces collagen-mediated tumorigenicity in pancreatic ductal adenocarcinoma.Breast cancer-associated fibroblasts: their roles in tumor initiation, progression and clinical applications.A mechanically active heterotypic E-cadherin/N-cadherin adhesion enables fibroblasts to drive cancer cell invasion.Preparation of High-Density Fibrillar Collagen Matrices That Mimic Desmoplastic Tumor Stroma.Biochemical and biomechanical drivers of cancer cell metastasis, drug response and nanomedicine Heralding a new paradigm in 3D tumor modeling.Physical and Chemical Gradients in the Tumor Microenvironment Regulate Tumor Cell Invasion, Migration, and Metastasis.The prognostic value and pathobiological significance of Glasgow microenvironment score in gastric cancer.Oxygen-dependent regulation of tumor growth and metastasis in human breast cancer xenografts.Tumor microenvironment indoctrination: an emerging hallmark of cancer.Capturing tumor complexity in vitro: Comparative analysis of 2D and 3D tumor models for drug discovery

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Why the stroma matters in breast cancer: insights into breast cancer patient outcomes through the examination of stromal biomarkers

http://www.wikidata.org/entity/Q27023385

description

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Dual role of macrophage migration inhibitory factor (MIF) in human breast cancer

Involvement of chemokine receptors in breast cancer metastasis

The complexities of breast cancer desmoplasia

Stromal effects on mammary gland development and breast cancer

Matrix crosslinking forces tumor progression by enhancing integrin signaling

Stromal cell expression of caveolin-1 predicts outcome in breast cancer

An absence of stromal caveolin-1 expression predicts early tumor recurrence and poor clinical outcome in human breast cancers

Greatly increased occurrence of breast cancers in areas of mammographically dense tissue

Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications

Gene expression profiling predicts clinical outcome of breast cancer

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