about
Preparative isolation and purification of anti-tumor agent ansamitocin P-3 from fermentation broth of Actinosynnema pretiosum using high-performance counter-current chromatography.Combinatorial effect of maytansinol and radiation in Drosophila and human cancer cells.An API LC/MS/MS quantitation method for ansamitocin P-3 (AP3) and its preclinical pharmacokinetics.Metabolism studies of the anti-tumor agent maytansine and its analog ansamitocin P-3 using liquid chromatography/tandem mass spectrometry.Constitutive overexpression of asm2 and asm39 increases AP-3 production in the actinomycete Actinosynnema pretiosum.Binding selectivity of rhizoxin, phomopsin A, vinblastine, and ansamitocin P-3 to fungal tubulins: differential interactions of these antimitotic agents with brain and fungal tubulins.Therapeutic effect of ansamitocin targeted to tumor by a bispecific monoclonal antibody.Enhanced production of ansamitocin P-3 by addition of Mg2+ in fermentation of Actinosynnema pretiosumEnhanced production of ansamitocin P-3 by addition of isobutanol in fermentation of Actinosynnema pretiosumAnsamitocin P-3, a maytansinoid, from Claopodium crispifolium and Anomodon attenuatus or associated actinomycetesCellular effects of leishmanial tubulin inhibitors on L. donovani
P921
Q33541602-55005455-AE52-4250-BDDC-D4103E16B4CBQ33877089-474B9BF9-758B-4C84-BE50-F3FC4ABB0859Q45144249-C6E1E736-A70B-4B7B-AC70-7A8AEB06A3F5Q45240756-2F2BEF8F-4AA7-4CB8-AB54-B81264CA4426Q45927181-7498E31D-BCF3-48D6-98E2-7E02D219F9B0Q48431358-3A13683E-CEDD-4749-9136-59784717DD5DQ55257821-1DA089CF-7C20-4E25-BD0A-DF7364C201C6Q57699853-78A8F05C-CBC6-450C-914C-B2CC14F7ED59Q57699857-3A38D8FD-178E-43F5-9CEE-1CA2352BD267Q68698793-15003FD1-CF6A-4FD1-9DB9-BD85932F819CQ73171856-047BA3E9-C785-4101-A2E1-88A3D4E4ACD8
P921
description
chemesch Verbindung
@lb
chemical compound
@en
chemical compound
@en-ca
chemical compound
@en-gb
chemická sloučenina
@cs
chemická zlúčenina
@sk
chemiese verbinding
@af
chemische Verbindung
@de
chemische Verbindung
@de-ch
chemische verbinding
@nl
name
ansamitomicin p-3
@en
type
label
ansamitomicin p-3
@en
altLabel
2'-De(acetylmethylamino)-2'-methylmaytansine
@en
Ansamitosin P3
@en
Antibiotic C15003P3
@en
C15003P3
@en
Maytansinol isobutyrate
@en
ansamitocin P-3
@en
prefLabel
ansamitomicin p-3
@en
P592
P661
P662
P665
P683
P1579
P2017
C[C@@H]1[C@@H]2C[C@]([C@@H](/C ...... C(=O)C(C)C)C)\C)OC)(NC(=O)O2)O
P2063
LMPK04000039
P2064
P2067
634.265709
P2175
P231
66584-72-3
P232
P233
CC1C2CC(C(C=CC=C(CC3=CC(=C(C(=C3)OC)Cl)N(C(=O)CC(C4(C1O4)C)OC(=O)C(C)C)C)C)OC)(NC(=O)O2)O
P234
1S/C32H43ClN2O9/c1-17(2)29(37) ...... ,23+,24-,25+,28+,31+,32+/m1/s1
P235
OPQNCARIZFLNLF-JBHFWYGFSA-N
P2566
100.205.792
P274
C₃₂H₄₃ClN₂O₉