Reducing GBA2 Activity Ameliorates Neuropathology in Niemann-Pick Type C Mice
about
Less Is More: Substrate Reduction Therapy for Lysosomal Storage DisordersThe sorting receptor Rer1 controls Purkinje cell function via voltage gated sodium channels.Bacterial β-Glucosidase Reveals the Structural and Functional Basis of Genetic Defects in Human Glucocerebrosidase 2 (GBA2).N-butyldeoxynojirimycin delays motor deficits, cerebellar microgliosis, and Purkinje cell loss in a mouse model of mucolipidosis type IV.Parkinson's disease: acid-glucocerebrosidase activity and alpha-synuclein clearance.Crosstalk between sphingolipids and vitamin D3: potential role in the nervous system.A Fluorescence Polarization Activity-Based Protein Profiling Assay in the Discovery of Potent, Selective Inhibitors for Human Nonlysosomal Glucosylceramidase.Chemical Proteomic Analysis of Serine Hydrolase Activity in Niemann-Pick Type C Mouse BrainGlucosylceramide synthase inhibition with lucerastat lowers globotriaosylceramide and lysosome staining in cultured fibroblasts from Fabry patients with different mutation types
P2860
Q26744230-B73759CA-9114-49F5-A9D3-CF35327D1DE7Q30836081-05973152-CB56-437F-BB53-C6A2F12C20F9Q37105361-C2BADFE5-099F-43B3-A010-FD1106248355Q38727163-09D1B07E-C666-47BE-9EDE-5A969509900DQ38727638-A1D3AE1C-71FF-48B4-A049-C42FB958D5F7Q39106107-A9F3DDEA-A41B-4FBF-9C13-B5801A765DCDQ47138226-C865F03B-279A-4C4F-9CFA-3CCD46504F0FQ57177300-43E43A70-3DA8-46E7-85B3-169E81E570A6Q58794894-988DEBB4-7094-4043-A9B3-B10A2FAE6FCB
P2860
Reducing GBA2 Activity Ameliorates Neuropathology in Niemann-Pick Type C Mice
description
2015 nî lūn-bûn
@nan
2015 թուականին հրատարակուած գիտական յօդուած
@hyw
2015 թվականին հրատարակված գիտական հոդված
@hy
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
name
Reducing GBA2 Activity Ameliorates Neuropathology in Niemann-Pick Type C Mice
@ast
Reducing GBA2 Activity Ameliorates Neuropathology in Niemann-Pick Type C Mice
@en
Reducing GBA2 Activity Ameliorates Neuropathology in Niemann-Pick Type C Mice
@nl
type
label
Reducing GBA2 Activity Ameliorates Neuropathology in Niemann-Pick Type C Mice
@ast
Reducing GBA2 Activity Ameliorates Neuropathology in Niemann-Pick Type C Mice
@en
Reducing GBA2 Activity Ameliorates Neuropathology in Niemann-Pick Type C Mice
@nl
prefLabel
Reducing GBA2 Activity Ameliorates Neuropathology in Niemann-Pick Type C Mice
@ast
Reducing GBA2 Activity Ameliorates Neuropathology in Niemann-Pick Type C Mice
@en
Reducing GBA2 Activity Ameliorates Neuropathology in Niemann-Pick Type C Mice
@nl
P2093
P2860
P50
P3181
P1433
P1476
Reducing GBA2 Activity Ameliorates Neuropathology in Niemann-Pick Type C Mice
@en
P2093
André R A Marques
Chris I De Zeeuw
Cindy P A A van Roomen
Daniela Herrera Moro
Johannes M F G Aerts
Kuikui Zhou
María Fernanda Vinueza Veloz
Mina Mirzaian
Nike Claessen
P2860
P304
P3181
P356
10.1371/JOURNAL.PONE.0135889
P407
P577
2015-01-01T00:00:00Z