A high-content small molecule screen identifies sensitivity of glioblastoma stem cells to inhibition of polo-like kinase 1
about
PLK1, A Potential Target for Cancer TherapyAccelerating glioblastoma drug discovery: Convergence of patient-derived models, genome editing and phenotypic screeningMolecular pathways: regulation and targeting of kinetochore-microtubule attachment in cancerCancer stem cells as a target population for drug discovery.Orthogonal targeting of EGFRvIII expressing glioblastomas through simultaneous EGFR and PLK1 inhibition.Epithelial-Mesenchymal Transition Predicts Polo-Like Kinase 1 Inhibitor-Mediated Apoptosis in Non-Small Cell Lung Cancer.Scalable Production of Glioblastoma Tumor-initiating Cells in 3 Dimension Thermoreversible Hydrogels.Glioblastoma Stem Cells Respond to Differentiation Cues but Fail to Undergo Commitment and Terminal Cell-Cycle Arrest.Spotlight on Volasertib: Preclinical and Clinical Evaluation of a Promising Plk1 Inhibitor.Sensitivity of TP53-Mutated Cancer Cells to the Phytoestrogen Genistein Is Associated With Direct Inhibition of Plk1 Activity.High-Throughput Imaging for the Discovery of Cellular Mechanisms of Disease.Primary porcine brain microvessel endothelial cell isolation and culture.Efficient CRISPR/Cas9-assisted gene targeting enables rapid and precise genetic manipulation of mammalian neural stem cells.The responses of cancer cells to PLK1 inhibitors reveal a novel protective role for p53 in maintaining centrosome separation.Proteome and Secretome Characterization of Glioblastoma-Derived Neural Stem Cells.The polo-like kinase 1 inhibitor volasertib synergistically increases radiation efficacy in glioma stem cells.
P2860
Q28078772-63FC0DBA-2D18-4E50-8D65-0735B79730B7Q28080068-A455CA06-1ED0-46A6-A6AB-F2783139426EQ34979651-F336E2C7-0D22-4BF1-895D-2D43FD2E6893Q35390334-B5F2F047-C579-4C73-B22F-A782D38A31F9Q35828426-52DF5D75-52D3-4168-BD47-89EAD9188776Q36759439-E76A5497-F284-4047-BD57-D888A32320EDQ37195569-5F1358D6-333A-470D-9232-0A1CE65138C0Q38816630-98B87DD7-D433-4EFF-BC34-9319EED53897Q38824242-04F7DA7E-3819-43C5-9367-244346FF3B95Q39175568-9D99E47C-E1B6-4BDC-B460-75B6E7791D76Q39451018-C859ED77-5ED2-4BD1-909F-0DDFAA4E1956Q41710205-8F130899-F6FA-4177-9722-406CB12E6A1BQ41833450-2CE57657-6602-44BA-9E39-663616A6A68BQ47135845-5C4D0577-4D34-47D1-91A9-00E888A7D96EQ48422165-D28275FD-6A88-4160-8F0C-9874C84B167AQ52726729-3786C23F-C6F1-49D8-81EB-7F63F119ABCF
P2860
A high-content small molecule screen identifies sensitivity of glioblastoma stem cells to inhibition of polo-like kinase 1
description
2013 nî lūn-bûn
@nan
2013 թուականին հրատարակուած գիտական յօդուած
@hyw
2013 թվականին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
A high-content small molecule ...... hibition of polo-like kinase 1
@ast
A high-content small molecule ...... hibition of polo-like kinase 1
@en
A high-content small molecule ...... hibition of polo-like kinase 1
@nl
type
label
A high-content small molecule ...... hibition of polo-like kinase 1
@ast
A high-content small molecule ...... hibition of polo-like kinase 1
@en
A high-content small molecule ...... hibition of polo-like kinase 1
@nl
prefLabel
A high-content small molecule ...... hibition of polo-like kinase 1
@ast
A high-content small molecule ...... hibition of polo-like kinase 1
@en
A high-content small molecule ...... hibition of polo-like kinase 1
@nl
P2093
P2860
P50
P3181
P1433
P1476
A high-content small molecule ...... hibition of polo-like kinase 1
@en
P2093
Ahmed M O Elbatsh
Ana Georgian
Christine Ender
Kevin J Harvey
Kin Pong U
N Joan Abbott
Patrick J Paddison
Patrizia Ferretti
Sabine Gogolok
P2860
P304
P3181
P356
10.1371/JOURNAL.PONE.0077053
P407
P50
P577
2013-01-01T00:00:00Z