Enhanced dimerization drives ligand-independent activity of mutant epidermal growth factor receptor in lung cancer
about
Orchestration of ErbB3 signaling through heterointeractions and homointeractions.Hydration effects on the efficacy of the Epidermal growth factor receptor kinase inhibitor afatinib.Quantum Dot-Based Nanotools for Bioimaging, Diagnostics, and Drug Delivery.Molecular basis for multimerization in the activation of the epidermal growth factor receptorBreaking the crosstalk of the cellular tumorigenic network: Hypothesis for addressing resistances to targeted therapies in advanced NSCLC.Cell signaling regulation by protein phosphorylation: a multivariate, heterogeneous, and context-dependent process.Extracellular region of epidermal growth factor receptor: a potential target for anti-EGFR drug discovery.Piecing it together: Unraveling the elusive structure-function relationship in single-pass membrane receptors.Activation of the EGF Receptor by Ligand Binding and Oncogenic Mutations: The "Rotation Model".The non-small cell lung cancer EGFR extracellular domain mutation, M277E, is oncogenic and drug-sensitive.Two-Color Single-Molecule Tracking in Live Cells.Pockets as structural descriptors of EGFR kinase conformations.Pharmaceutical potential of quantum dots.EGFR Ligands Differentially Stabilize Receptor Dimers to Specify Signaling Kinetics.Differential mast cell outcomes are sensitive to FcεRI-Syk binding kinetics.The dimer-dependent catalytic activity of RAF family kinases is revealed through characterizing their oncogenic mutantsThe architecture of EGFR's basal complexes reveals autoinhibition mechanisms in dimers and oligomers
P2860
Q27306737-C9494332-D94F-4D4F-B4A4-76C1095962A9Q29994744-F8BF3867-06D6-465F-AE88-DF5E6A639A10Q31122176-EE034C3D-F480-46DA-95A9-1150AC8071D5Q36993693-B24B5F97-3A19-4252-8595-9A7E04ACA276Q38840383-F1362684-A51E-4CA9-83D2-36AA9D58CBF4Q38890784-E7D1DB16-5A72-42C7-B447-F2A1E99CAFBAQ38989275-87B166FA-459B-436A-891B-FB4B1CEC069CQ39089524-C6A0370D-DA80-4882-9DB6-E7BCF8A9570BQ39346046-6853A345-8BA2-477A-8D82-B534D57C2BA3Q42360041-C1744C1F-58C1-4C65-AE2D-446883CB2699Q46304711-F1ECEC67-3610-41B1-BE8E-9C3121EF5737Q47162698-7C2FE137-E625-49C7-A286-E8DC1E6BE989Q47272061-0B6D6DEE-B34B-4A98-8ADD-5EC45CBBEAAAQ47680913-B5C52345-177E-475A-8C0F-46D59A625831Q49605860-27D7518B-2BB7-403A-9F29-D27E59F56D82Q58056531-D74DCC38-10CC-4501-9DBE-2CFF6EC22BDCQ58600328-1BFC5DAC-4781-4992-8B6F-FBC23A303761
P2860
Enhanced dimerization drives ligand-independent activity of mutant epidermal growth factor receptor in lung cancer
description
2015 nî lūn-bûn
@nan
2015 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2015 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
name
Enhanced dimerization drives l ...... factor receptor in lung cancer
@ast
Enhanced dimerization drives l ...... factor receptor in lung cancer
@en
Enhanced dimerization drives l ...... factor receptor in lung cancer
@nl
type
label
Enhanced dimerization drives l ...... factor receptor in lung cancer
@ast
Enhanced dimerization drives l ...... factor receptor in lung cancer
@en
Enhanced dimerization drives l ...... factor receptor in lung cancer
@nl
prefLabel
Enhanced dimerization drives l ...... factor receptor in lung cancer
@ast
Enhanced dimerization drives l ...... factor receptor in lung cancer
@en
Enhanced dimerization drives l ...... factor receptor in lung cancer
@nl
P2093
P2860
P3181
P356
P1476
Enhanced dimerization drives l ...... factor receptor in lung cancer
@en
P2093
Alexey I Chizhik
Bridget S Wilson
Christopher C Valley
Diane S Lidke
Donna J Arndt-Jovin
Keith A Lidke
Mara P Steinkamp
Narain Karedla
P2860
P304
P3181
P356
10.1091/MBC.E15-05-0269
P577
2015-09-02T00:00:00Z