Viable neuronopathic Gaucher disease model in Medaka (Oryzias latipes) displays axonal accumulation of alpha-synuclein - Test2 - elhamkhani - TriplyDB

Viable neuronopathic Gaucher disease model in Medaka (Oryzias latipes) displays axonal accumulation of alpha-synuclein

Viable neuronopathic Gaucher disease model in Medaka (Oryzias latipes) displays axonal accumulation of alpha-synuclein

http://www.wikidata.org/entity/Q27311396

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Glucocerebrosidase 1 deficient Danio rerio mirror key pathological aspects of human Gaucher disease and provide evidence of early microglial activation preceding alpha-synuclein-independent neuronal cell death In vivo Magnetic Resonance Microscopy and Hypothermic Anaesthesia of a Disease Model in Medaka Did α-Synuclein and Glucocerebrosidase Coevolve? Implications for Parkinson's Disease.Glucocerebrosidase Deficiency in Drosophila Results in α-Synuclein-Independent Protein Aggregation and Neurodegeneration.Parkinson's disease pathogenesis from the viewpoint of small fish models.Dopamine system, cerebellum, and nucleus ruber in fish and mammals.Association of GBA Mutations and the E326K Polymorphism With Motor and Cognitive Progression in Parkinson Disease.An optimized method for counting dopaminergic neurons in zebrafish.Mitochondrial Dysfunction in Lysosomal Storage Disorders.Altered Differentiation Potential of Gaucher's Disease iPSC Neuronal Progenitors due to Wnt/β-Catenin Downregulation.Generation of a transgenic medaka (Oryzias latipes) strain for visualization of nuclear dynamics in early developmental stages.Quantitative morphometric analysis of adult teleost fish by X-ray computed tomography Glucocerebrosidase deficiency promotes protein aggregation through dysregulation of extracellular vesicles

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P2860

Viable neuronopathic Gaucher disease model in Medaka (Oryzias latipes) displays axonal accumulation of alpha-synuclein

http://www.wikidata.org/entity/Q27311396

description

2015 nî lūn-bûn

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2015 թուականի Ապրիլին հրատարակուած գիտական յօդուած

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2015 թվականի ապրիլին հրատարակված գիտական հոդված

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2015年の論文

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2015年論文

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2015年論文

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2015年論文

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2015年論文

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2015年論文

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name

Viable neuronopathic Gaucher d ...... ccumulation of alpha-synuclein

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Viable neuronopathic Gaucher d ...... ccumulation of alpha-synuclein

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Viable neuronopathic Gaucher d ...... ccumulation of alpha-synuclein

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Viable neuronopathic Gaucher d ...... ccumulation of alpha-synuclein

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Viable neuronopathic Gaucher d ...... ccumulation of alpha-synuclein

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Viable neuronopathic Gaucher d ...... ccumulation of alpha-synuclein

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Viable neuronopathic Gaucher d ...... ccumulation of alpha-synuclein

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Hideaki Matsui

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Hodaka Yamakado

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Kiyoshi Naruse

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Masato Kinoshita

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Ryosuke Takahashi

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Takeshi Todo

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Tomoko Ishikawa-Fujiwara

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Yasuo Uchiyama

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P2860

Gaucher disease glucocerebrosidase and α-synuclein form a bidirectional pathogenic loop in synucleinopathies

Reduced glucocerebrosidase is associated with increased α-synuclein in sporadic Parkinson's disease

Disrupted autophagy leads to dopaminergic axon and dendrite degeneration and promotes presynaptic accumulation of α-synuclein and LRRK2 in the brain

Autophagy in lysosomal storage disorders

Multicenter analysis of glucocerebrosidase mutations in Parkinson's disease.

Glucocerebrosidase mutations in clinical and pathologically proven Parkinson's disease

ATP13A2 deficiency induces a decrease in cathepsin D activity, fingerprint-like inclusion body formation, and selective degeneration of dopaminergic neurons

Consequences of beta-glucocerebrosidase deficiency in epidermis. Ultrastructure and permeability barrier alterations in Gaucher disease

Pale body-like inclusion formation and neurodegeneration following depletion of 26S proteasomes in mouse brain neurones are independent of α-synuclein

Mice lacking alpha-synuclein display functional deficits in the nigrostriatal dopamine system

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Tomoko Ishikawa-Fujiwara

Norihito Uemura

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Naoaki Sakamoto

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2015-04-01T00:00:00Z

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274396639

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25835295

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Japanese rice fish

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4383526

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