Ebolavirus is internalized into host cells via macropinocytosis in a viral glycoprotein-dependent manner
about
Lectin-dependent enhancement of Ebola virus infection via soluble and transmembrane C-type lectin receptorsIntracellular events and cell fate in filovirus infectionT-cell immunoglobulin and mucin domain 1 (TIM-1) is a receptor for Zaire Ebolavirus and Lake Victoria MarburgvirusThe Tyro3 receptor kinase Axl enhances macropinocytosis of Zaire ebolavirusSmall molecule inhibitors reveal Niemann-Pick C1 is essential for Ebola virus infectionEbola virus entry requires the cholesterol transporter Niemann-Pick C1Pyridinyl imidazole inhibitors of p38 MAP kinase impair viral entry and reduce cytokine induction by Zaire ebolavirus in human dendritic cellsFDA-approved selective estrogen receptor modulators inhibit Ebola virus infection.Ebola virus entry requires the host-programmed recognition of an intracellular receptorPhosphatidylserine receptors: enhancers of enveloped virus entry and infectionMarburg Virus Reverse Genetics SystemsEbolavirus entry requires a compact hydrophobic fist at the tip of the fusion loop.Host-Primed Ebola Virus GP Exposes a Hydrophobic NPC1 Receptor-Binding Pocket, Revealing a Target for Broadly Neutralizing AntibodiesFusion of Enveloped Viruses in Endosomes.Compounds with anti-influenza activity: present and future of strategies for the optimal treatment and management of influenza. Part I: Influenza life-cycle and currently available drugsThe Synthetic Antiviral Drug Arbidol Inhibits Globally Prevalent Pathogenic VirusesMultiple cationic amphiphiles induce a Niemann-Pick C phenotype and inhibit Ebola virus entry and infectionsiRNA Screen Identifies Trafficking Host Factors that Modulate Alphavirus InfectionThe face of Ebola: changing frequency of haemorrhage in the West African compared with Eastern-Central African outbreaksAnti-Ebola therapies based on monoclonal antibodies: current state and challenges ahead.The phosphatidylinositol-3-phosphate 5-kinase inhibitor apilimod blocks filoviral entry and infectionThe Roles of Histidines and Charged Residues as Potential Triggers of a Conformational Change in the Fusion Loop of Ebola Virus Glycoprotein.A screen of approved drugs and molecular probes identifies therapeutics with anti-Ebola virus activity.Discovery of an antibody for pan-ebolavirus therapyInteraction between TIM-1 and NPC1 Is Important for Cellular Entry of Ebola Virus.New Perspectives on Ebola Virus EvolutionA new player in the puzzle of filovirus entry.Combining single RNA sensitive probes with subdiffraction-limited and live-cell imaging enables the characterization of virus dynamics in cells.Entry of a novel marine DNA virus, Singapore grouper iridovirus, into host cells occurs via clathrin-mediated endocytosis and macropinocytosis in a pH-dependent manner.Structure of the Ebola virus glycoprotein spike within the virion envelope at 11 Å resolution.The Ras-PI3K signaling pathway is involved in clathrin-independent endocytosis and the internalization of influenza viruses.Human metapneumovirus SH and G glycoproteins inhibit macropinocytosis-mediated entry into human dendritic cells and reduce CD4+ T cell activationEndocytosis of viruses and bacteria.Infection of XC cells by MLVs and Ebola virus is endosome-dependent but acidification-independent.Interplay between innate immunity and negative-strand RNA viruses: towards a rational modelSorting nexin 24 genetic variation associates with coronary artery aneurysm severity in Kawasaki disease patients.A novel life cycle modeling system for Ebola virus shows a genome length-dependent role of VP24 in virus infectivityThe spatio-temporal distribution dynamics of Ebola virus proteins and RNA in infected cellsThe clinically approved drugs amiodarone, dronedarone and verapamil inhibit filovirus cell entry.Cell entry by a novel European filovirus requires host endosomal cysteine proteases and Niemann-Pick C1.
P2860
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P2860
Ebolavirus is internalized into host cells via macropinocytosis in a viral glycoprotein-dependent manner
description
2010 nî lūn-bûn
@nan
2010 թուականին հրատարակուած գիտական յօդուած
@hyw
2010 թվականին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Ebolavirus is internalized int ...... glycoprotein-dependent manner
@ast
Ebolavirus is internalized int ...... glycoprotein-dependent manner
@en
Ebolavirus is internalized int ...... glycoprotein-dependent manner
@nl
type
label
Ebolavirus is internalized int ...... glycoprotein-dependent manner
@ast
Ebolavirus is internalized int ...... glycoprotein-dependent manner
@en
Ebolavirus is internalized int ...... glycoprotein-dependent manner
@nl
prefLabel
Ebolavirus is internalized int ...... glycoprotein-dependent manner
@ast
Ebolavirus is internalized int ...... glycoprotein-dependent manner
@en
Ebolavirus is internalized int ...... glycoprotein-dependent manner
@nl
P2093
P2860
P3181
P1433
P1476
Ebolavirus is internalized int ...... glycoprotein-dependent manner
@en
P2093
Gabriele Neumann
Kei Takahashi
Masaki Imai
Peter Halfmann
Shinji Watanabe
Takeshi Noda
P2860
P304
P3181
P356
10.1371/JOURNAL.PPAT.1001121
P407
P577
2010-01-01T00:00:00Z