A γ-secretase inhibitor, but not a γ-secretase modulator, induced defects in BDNF axonal trafficking and signaling: evidence for a role for APP
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Therapies for Prevention and Treatment of Alzheimer's DiseaseThe involvement of BDNF, NGF and GDNF in aging and Alzheimer's diseaseFunctional Impact of Corticotropin-Releasing Factor Exposure on Tau Phosphorylation and Axon TransportAmyloid precursor protein-mediated endocytic pathway disruption induces axonal dysfunction and neurodegenerationEnhanced neuroinvasion by smaller, soluble prions.Synuclein impairs trafficking and signaling of BDNF in a mouse model of Parkinson's disease.Metabolic Characterization of Intact Cells Reveals Intracellular Amyloid Beta but Not Its Precursor Protein to Reduce Mitochondrial Respiration.Partial BACE1 reduction in a Down syndrome mouse model blocks Alzheimer-related endosomal anomalies and cholinergic neurodegeneration: role of APP-CTF.An Anti-β-Amyloid Vaccine for Treating Cognitive Deficits in a Mouse Model of Down Syndrome.TRiC subunits enhance BDNF axonal transport and rescue striatal atrophy in Huntington's diseaseDefective Transcytosis of APP and Lipoproteins in Human iPSC-Derived Neurons with Familial Alzheimer's Disease Mutations.MH84: A Novel γ-Secretase Modulator/PPARγ Agonist--Improves Mitochondrial Dysfunction in a Cellular Model of Alzheimer's Disease.PINK1 signalling rescues amyloid pathology and mitochondrial dysfunction in Alzheimer's disease.Dysregulation of neurotrophin signaling in the pathogenesis of Alzheimer disease and of Alzheimer disease in Down syndrome.Dysregulation of Rab5-Mediated Endocytic Pathways in Alzheimer's Disease.Swedish Nerve Growth Factor Mutation (NGFR100W) Defines a Role for TrkA and p75NTR in Nociception.
P2860
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P2860
A γ-secretase inhibitor, but not a γ-secretase modulator, induced defects in BDNF axonal trafficking and signaling: evidence for a role for APP
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2015年の論文
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2015年論文
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2015年論文
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name
A γ-secretase inhibitor, but n ...... g: evidence for a role for APP
@ast
A γ-secretase inhibitor, but n ...... g: evidence for a role for APP
@en
A γ-secretase inhibitor, but n ...... g: evidence for a role for APP
@nl
type
label
A γ-secretase inhibitor, but n ...... g: evidence for a role for APP
@ast
A γ-secretase inhibitor, but n ...... g: evidence for a role for APP
@en
A γ-secretase inhibitor, but n ...... g: evidence for a role for APP
@nl
prefLabel
A γ-secretase inhibitor, but n ...... g: evidence for a role for APP
@ast
A γ-secretase inhibitor, but n ...... g: evidence for a role for APP
@en
A γ-secretase inhibitor, but n ...... g: evidence for a role for APP
@nl
P2093
P2860
P3181
P1433
P1476
A γ-secretase inhibitor, but n ...... g: evidence for a role for APP
@en
P2093
April M Weissmiller
Chengbiao Wu
Lawrence S B Goldstein
Matthew L Pearn
Orlangie Natera-Naranjo
Phuong Nguyen
Soan Cheng
Sol M Reyna
Steven L Wagner
William C Mobley
P2860
P304
P3181
P356
10.1371/JOURNAL.PONE.0118379
P407
P577
2015-01-01T00:00:00Z