The Aurora Kinase in Trypanosoma brucei plays distinctive roles in metaphase-anaphase transition and cytokinetic initiation
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Nuclear DBF-2-related kinases are essential regulators of cytokinesis in bloodstream stage Trypanosoma bruceiKinases as druggable targets in trypanosomatid protozoan parasitesAurora at the pole and equator: overlapping functions of Aurora kinases in the mitotic spindleTwo distinct cytokinesis pathways drive trypanosome cell division initiation from opposite cell ends.Structure-function analysis of dynein light chain 1 identifies viable motility mutants in bloodstream-form Trypanosoma brucei.The Aurora B kinase in Trypanosoma brucei undergoes post-translational modifications and is targeted to various subcellular locations through binding to TbCPC1.Motility and more: the flagellum of Trypanosoma brucei.Trypanosome outer kinetochore proteins suggest conservation of chromosome segregation machinery across eukaryotes.The Cdc45·Mcm2-7·GINS protein complex in trypanosomes regulates DNA replication and interacts with two Orc1-like proteins in the origin recognition complex.Structure-function relationship of the Polo-like kinase in Trypanosoma brucei.Proteomic identification of novel cytoskeletal proteins associated with TbPLK, an essential regulator of cell morphogenesis in Trypanosoma bruceiA Novel Basal Body Protein That Is a Polo-like Kinase Substrate Is Required for Basal Body Segregation and Flagellum Adhesion in Trypanosoma bruceiThe Trypanosoma brucei AIR9-like protein is cytoskeleton-associated and is required for nucleus positioning and accurate cleavage furrow placement.SAS-4 Protein in Trypanosoma brucei Controls Life Cycle Transitions by Modulating the Length of the Flagellum Attachment Zone FilamentDynein Light Chain LC8 Is Required for RNA Polymerase I-Mediated Transcription in Trypanosoma brucei, Facilitating Assembly and Promoter Binding of Class I Transcription Factor AThe human Aurora kinase inhibitor danusertib is a lead compound for anti-trypanosomal drug discovery via target repurposing.An EF-hand-containing Protein in Trypanosoma brucei Regulates Cytokinesis Initiation by Maintaining the Stability of the Cytokinesis Initiation Factor CIF1.Promoter occupancy of the basal class I transcription factor A differs strongly between active and silent VSG expression sites in Trypanosoma brucei.Regulation of the cell division cycle in Trypanosoma brucei.Evolutionary cell biology of chromosome segregation: insights from trypanosomes.More than meets the eye: understanding Trypanosoma brucei morphology in the tsetse.New insights into the molecular mechanisms of mitosis and cytokinesis in trypanosomesGenome-wide and protein kinase-focused RNAi screens reveal conserved and novel damage response pathways in Trypanosoma brucei.Repurposing human Aurora kinase inhibitors as leads for anti-protozoan drug discovery.A kinetoplastid-specific kinesin is required for cytokinesis and for maintenance of cell morphology in Trypanosoma bruceiA backup cytokinesis pathway in Trypanosoma brucei.Functional analyses of the CIF1-CIF2 complex in trypanosomes identify the structural motifs required for cytokinesis.A trypanosome-specific protein cooperates with the CIF1 protein to promote cytokinesis in Trypanosoma brucei.
P2860
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P2860
The Aurora Kinase in Trypanosoma brucei plays distinctive roles in metaphase-anaphase transition and cytokinetic initiation
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2009 nî lūn-bûn
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2009 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
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2009 թվականի սեպտեմբերին հրատարակված գիտական հոդված
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2009年の論文
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2009年学术文章
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2009年学术文章
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The Aurora Kinase in Trypanoso ...... ion and cytokinetic initiation
@ast
The Aurora Kinase in Trypanoso ...... ion and cytokinetic initiation
@en
The Aurora Kinase in Trypanoso ...... ion and cytokinetic initiation
@nl
type
label
The Aurora Kinase in Trypanoso ...... ion and cytokinetic initiation
@ast
The Aurora Kinase in Trypanoso ...... ion and cytokinetic initiation
@en
The Aurora Kinase in Trypanoso ...... ion and cytokinetic initiation
@nl
prefLabel
The Aurora Kinase in Trypanoso ...... ion and cytokinetic initiation
@ast
The Aurora Kinase in Trypanoso ...... ion and cytokinetic initiation
@en
The Aurora Kinase in Trypanoso ...... ion and cytokinetic initiation
@nl
P2093
P2860
P1433
P1476
The Aurora Kinase in Trypanoso ...... ion and cytokinetic initiation
@en
P2093
Takashi Umeyama
P2860
P304
P356
10.1371/JOURNAL.PPAT.1000575
P407
P577
2009-09-01T00:00:00Z