PICK1 and ICA69 control insulin granule trafficking and their deficiencies lead to impaired glucose tolerance
about
Membrane Binding and Modulation of the PDZ Domain of PICK1The EARP Complex and Its Interactor EIPR-1 Are Required for Cargo Sorting to Dense-Core VesiclesPICK1 deficiency impairs secretory vesicle biogenesis and leads to growth retardation and decreased glucose toleranceSyntabulin regulates the trafficking of PICK1-containing vesicles in neurons.Protein interacting with C-kinase 1 (PICK1) binding promiscuity relies on unconventional PSD-95/discs-large/ZO-1 homology (PDZ) binding modes for nonclass II PDZ ligands.SORCS1 is necessary for normal insulin secretory granule biogenesis in metabolically stressed β cells.Structure of Dimeric and Tetrameric Complexes of the BAR Domain Protein PICK1 Determined by Small-Angle X-Ray Scattering.Compromised central tolerance of ICA69 induces multiple organ autoimmunity.Rescuing infertility of Pick1 knockout mice by generating testis-specific transgenic mice via testicular infectionHID-1 is required for homotypic fusion of immature secretory granules during maturation.The dynamic plasticity of insulin production in β-cells.The BAR domain protein PICK1 controls vesicle number and size in adrenal chromaffin cells.The SNARE protein vti1a functions in dense-core vesicle biogenesisPICK1 is Essential for Insulin Production and the Maintenance of Glucose Homeostasis.HID-1 controls formation of large dense core vesicles by influencing cargo sorting and trans-Golgi network acidification.Loss of ICA69 potentiates long-lasting hyperalgesia after subcutaneous formalin injection into the mouse hindpaw.The dense-core vesicle maturation protein CCCP-1 binds RAB-2 and membranes through its C-terminal domain.Control of Insulin Granule Formation and Function by the ABC Transporters ABCG1 and ABCA1 and by Oxysterol Binding Protein OSBP.Protein Interacting C-Kinase 1 Modulates Surface Expression of P2Y6 Purinoreceptor, Actin Polymerization and Phagocytosis in Microglia.Arc/Arg3.1 has an activity-regulated interaction with PICK1 that results in altered spatial dynamicsUnexpected subcellular distribution of a specific isoform of the Coxsackie and adenovirus receptor, CAR-SIV, in human pancreatic beta cells
P2860
Q26778952-435A19CB-89D4-4C6A-8177-5E9F5345D895Q27308807-B2C0149A-59B7-4DED-8D7D-E67247D5ADCBQ27317876-98329B44-ED3A-4054-918D-C5E97566D85AQ27349717-0758B2FF-FF6A-4361-9053-E153C8293E1BQ30364686-7CDE24C8-3C08-4B08-BE91-7FD0AFE43E7CQ34311608-36428CE4-A910-4E7D-AD32-DF9E6F467081Q35851692-9454A3DF-CE0E-400C-A5EE-3AC4CA3FD450Q36440605-DCA255E7-C0B9-4D88-A5CD-4977C34670D1Q37219961-3F0AB48C-4877-44D7-AE81-C1E445926B6EQ37392295-55A71BF9-2773-435B-8122-D30CB9E49E11Q41689708-2BA41998-C7F7-4C58-BAF7-C61F67DA0B62Q42201521-51ABE66F-DAFF-4DD0-8A47-AAF4CEA97E16Q42548237-418A5015-6ACA-4C4D-B22A-1A7AD9944C69Q47212904-7247A32C-2385-432A-991D-38E96EBAA3D1Q47598409-F1D057E9-5062-4003-AEE8-9E4D903CF6CCQ47769034-029B086B-2FE2-407E-A81B-255A0DBC05F1Q48013887-E2F813BB-F313-4A65-9A23-B56069BD3E06Q52726541-ED27E097-9FB2-45B1-AFC8-23A582421991Q53278292-20B5B2D1-2BCD-42A8-862E-AA5F9E9B55FBQ57050434-587B1EF4-BD25-4443-940D-7EE9DD29F76AQ57920489-B803BDCA-EE5F-4077-871C-DDBCBB5FC0AF
P2860
PICK1 and ICA69 control insulin granule trafficking and their deficiencies lead to impaired glucose tolerance
description
2013 թուականին հրատարակուած գիտական յօդուած
@hyw
2013 թվականին հրատարակված գիտական հոդված
@hy
article scientifique (publié 2013)
@fr
articolo scientifico (pubblicato il 2013)
@it
artigo científico (publicado na 2013)
@pt
artículu científicu espublizáu en 2013
@ast
im Januar 2013 veröffentlichter wissenschaftlicher Artikel
@de
scientific article (publication date: 2013)
@en
vedecký článok (publikovaný 2013)
@sk
videnskabelig artikel (udgivet 2013)
@da
name
PICK1 and ICA69 control insuli ...... to impaired glucose tolerance
@ast
PICK1 and ICA69 control insuli ...... to impaired glucose tolerance
@en
PICK1 and ICA69 control insuli ...... to impaired glucose tolerance
@nl
type
label
PICK1 and ICA69 control insuli ...... to impaired glucose tolerance
@ast
PICK1 and ICA69 control insuli ...... to impaired glucose tolerance
@en
PICK1 and ICA69 control insuli ...... to impaired glucose tolerance
@nl
prefLabel
PICK1 and ICA69 control insuli ...... to impaired glucose tolerance
@ast
PICK1 and ICA69 control insuli ...... to impaired glucose tolerance
@en
PICK1 and ICA69 control insuli ...... to impaired glucose tolerance
@nl
P2093
P2860
P921
P3181
P1433
P1476
PICK1 and ICA69 control insuli ...... to impaired glucose tolerance
@en
P2093
Chong Shen
Kenneth K Y Cheng
Kwong-Man Lee
Liwen Jiang
Xiaoxing Cao
P2860
P304
P3181
P356
10.1371/JOURNAL.PBIO.1001541
P407
P577
2013-01-01T00:00:00Z