Rational design of small molecule inhibitors targeting the Ras GEF, SOS1.
about
Combined rational design and a high throughput screening platform for identifying chemical inhibitors of a Ras-activating enzymeInhibitors of Ras-SOS Interactions.Screening-based translation of public research encounters painful problems.A genome-wide siRNA screen for regulators of tumor suppressor p53 activity in human non-small cell lung cancer cells identifies components of the RNA splicing machinery as targets for anticancer treatment.Sleeping Beauty transposon screen identifies signaling modules that cooperate with STAT5 activation to induce B-cell acute lymphoblastic leukemiaSOS1, ARHGEF1, and DOCK2 rho-GEFs Mediate JAK-Dependent LFA-1 Activation by Chemokines.Next-generation molecular therapy in lung cancer.
P2860
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P2860
Rational design of small molecule inhibitors targeting the Ras GEF, SOS1.
description
2014 nî lūn-bûn
@nan
2014 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Rational design of small molecule inhibitors targeting the Ras GEF, SOS1
@nl
Rational design of small molecule inhibitors targeting the Ras GEF, SOS1.
@ast
Rational design of small molecule inhibitors targeting the Ras GEF, SOS1.
@en
type
label
Rational design of small molecule inhibitors targeting the Ras GEF, SOS1
@nl
Rational design of small molecule inhibitors targeting the Ras GEF, SOS1.
@ast
Rational design of small molecule inhibitors targeting the Ras GEF, SOS1.
@en
prefLabel
Rational design of small molecule inhibitors targeting the Ras GEF, SOS1
@nl
Rational design of small molecule inhibitors targeting the Ras GEF, SOS1.
@ast
Rational design of small molecule inhibitors targeting the Ras GEF, SOS1.
@en
P2093
P2860
P1476
Rational design of small molecule inhibitors targeting the Ras GEF, SOS1
@en
P2093
Chris R Evelyn
Jacek Biesiada
William L Seibel
P2860
P304
P356
10.1016/J.CHEMBIOL.2014.09.018
P50
P577
2014-11-20T00:00:00Z