Fatty acid desaturation links germ cell loss to longevity through NHR-80/HNF4 in C. elegans - Test2 - elhamkhani - TriplyDB

Fatty acid desaturation links germ cell loss to longevity through NHR-80/HNF4 in C. elegans

Fatty acid desaturation links germ cell loss to longevity through NHR-80/HNF4 in C. elegans

http://www.wikidata.org/entity/Q27322410

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Lessons from C. elegans: signaling pathways for longevity Using Caenorhabditis elegans to Uncover Conserved Functions of Omega-3 and Omega-6 Fatty Acids Physiological control of germline development DAF-16 and TCER-1 Facilitate Adaptation to Germline Loss by Restoring Lipid Homeostasis and Repressing Reproductive Physiology in C. elegans Germline signals deploy NHR-49 to modulate fatty-acid β-oxidation and desaturation in somatic tissues of C. elegans A novel 3-hydroxysteroid dehydrogenase that regulates reproductive development and longevity A functional genomic screen for evolutionarily conserved genes required for lifespan and immunity in germline-deficient C. elegans Dietary restriction induced longevity is mediated by nuclear receptor NHR-62 in Caenorhabditis elegans Fluorodeoxyuridine improves Caenorhabditis elegans proteostasis independent of reproduction onset Genome-wide analysis of germline signaling genes regulating longevity and innate immunity in the nematode Pristionchus pacificus Mediation of organismal aging and somatic proteostasis by the germline A steroid receptor-microRNA switch regulates life span in response to signals from the gonad Gain-of-Function Alleles in Caenorhabditis elegans Nuclear Hormone Receptor nhr-49 Are Functionally Distinct Metabolomic signature associated with reproduction-regulated aging in Caenorhabditis elegans Alternative Perspectives on Aging in Caenorhabditis elegans: Reactive Oxygen Species or Hyperfunction?Uncoupling the Trade-Off between Somatic Proteostasis and Reproduction in Caenorhabditis elegans Models of Polyglutamine Diseases.New Therapeutics to Modulate Mitochondrial Function in Neurodegenerative Disorders.Cytochrome b5 reductase and the control of lipid metabolism and healthspan.Organismal proteostasis: role of cell-nonautonomous regulation and transcellular chaperone signaling.Lipid profiles of female and male Drosophila Caenorhabditis elegans metabolic gene regulatory networks govern the cellular economy.Mulberry leaf polyphenols delay aging and regulate fat metabolism via the germline signaling pathway in Caenorhabditis elegans Aging. Lysosomal signaling molecules regulate longevity in Caenorhabditis elegans.AMPK at the nexus of energetics and aging.New genes that extend Caenorhabditis elegans' lifespan in response to reproductive signals.Function and Regulation of Lipid Biology in Caenorhabditis elegans Aging.Lipid-mediated regulation of SKN-1/Nrf in response to germ cell absence.The mysterious relationship between reproduction and longevity.Vitellogenin-RNAi and ovariectomy each increase lifespan, increase protein storage, and decrease feeding, but are not additive in grasshoppers.Transcriptional analysis reveals a high impact of conjugated linoleic acid on stearoyl-Coenzyme A desaturase 1 mRNA expression in mice gastrocnemius muscle.Innate immunity mediated longevity and longevity induced by germ cell removal converge on the C-type lectin domain protein IRG-7.Stress response pathways protect germ cells from omega-6 polyunsaturated fatty acid-mediated toxicity in Caenorhabditis elegans.Reproduction, fat metabolism, and life span: what is the connection?Regulation of longevity by the reproductive system.Mondo complexes regulate TFEB via TOR inhibition to promote longevity in response to gonadal signals Nuclear hormone receptors as mediators of metabolic adaptability following reproductive perturbations.Autophagy-mediated longevity is modulated by lipoprotein biogenesis.Roles for ROS and hydrogen sulfide in the longevity response to germline loss in Caenorhabditis elegans.Life-extending ovariectomy in grasshoppers increases somatic storage, but dietary restriction with an equivalent feeding rate does not C30F12.4 influences oogenesis, fat metabolism, and lifespan in C. elegans.

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Fatty acid desaturation links germ cell loss to longevity through NHR-80/HNF4 in C. elegans

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2011 nî lūn-bûn

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Fatty acid desaturation links ...... ough NHR-80/HNF4 in C. elegans

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Fatty acid desaturation links ...... ough NHR-80/HNF4 in C. elegans

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Esther Toselli-Mollereau

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Hugo Aguilaniu

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Jérôme Goudeau

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Mehrnaz Shamalnasab

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Stéphanie Bellemin

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Yiqun Chen

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P2860

Genetic regulation of unsaturated fatty acid composition in C. elegans

Hepatocyte nuclear factor 4 is a transcription factor that constitutively binds fatty acids

The genetics of Caenorhabditis elegans

New genes tied to endocrine, metabolic, and dietary regulation of lifespan from a Caenorhabditis elegans genomic RNAi screen.

A RAPID METHOD OF TOTAL LIPID EXTRACTION AND PURIFICATION

The somatic reproductive tissues of C. elegans promote longevity through steroid hormone signaling

A transcription elongation factor that links signals from the reproductive system to lifespan extension in Caenorhabditis elegans

Crystal structure of the HNF4 alpha ligand binding domain in complex with endogenous fatty acid ligand

Genes that act downstream of DAF-16 to influence the lifespan of Caenorhabditis elegans

A C. elegans mutant that lives twice as long as wild type

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Caenorhabditis elegans

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