APP intracellular domain impairs adult neurogenesis in transgenic mice by inducing neuroinflammation - Test2 - elhamkhani - TriplyDB

APP intracellular domain impairs adult neurogenesis in transgenic mice by inducing neuroinflammation

APP intracellular domain impairs adult neurogenesis in transgenic mice by inducing neuroinflammation

http://www.wikidata.org/entity/Q27322677

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Molecular Mechanism of Adult Neurogenesis and its Association with Human Brain Diseases Tau Protein Mediates APP Intracellular Domain (AICD)-Induced Alzheimer's-Like Pathological Features in Mice Methylene Blue (Tetramethylthionine Chloride) Influences the Mobility of Adult Neural Stem Cells: A Potentially Novel Therapeutic Mechanism of a Therapeutic Approach in the Treatment of Alzheimer's Disease.Systemic immune challenges trigger and drive Alzheimer-like neuropathology in mice.Adult hippocampal neurogenesis and mRNA expression are altered by perinatal arsenic exposure in mice and restored by brief exposure to enrichment.Neurogenic abnormalities in Alzheimer's disease differ between stages of neurogenesis and are partly related to cholinergic pathology Adult hippocampal neurogenesis and its role in Alzheimer's disease When neurogenesis encounters aging and disease Generation of anti-Notch antibodies and their application in blocking Notch signalling in neural stem cells.Model Hirano bodies protect against tau-independent and tau-dependent cell death initiated by the amyloid precursor protein intracellular domain.More than cholesterol transporters: lipoprotein receptors in CNS function and neurodegeneration Manipulations of amyloid precursor protein cleavage disrupt the circadian clock in aging Drosophila.Neuroinflammatory Cytokines-The Common Thread in Alzheimer's Pathogenesis All in the Family: How the APPs Regulate Neurogenesis APP intracellular domain acts as a transcriptional regulator of miR-663 suppressing neuronal differentiation.Human tau expression reduces adult neurogenesis in a mouse model of tauopathy Inhibition of APP gamma-secretase restores Sonic Hedgehog signaling and neurogenesis in the Ts65Dn mouse model of Down syndrome Abca7 deletion does not affect adult neurogenesis in the mouse.Soluble amyloid precursor protein-α rescues age-linked decline in neural progenitor cell proliferation Pharmacological targeting of the β-amyloid precursor protein intracellular domain.Amyloid-independent mechanisms in Alzheimer's disease pathogenesis Is it possible to improve neurodevelopmental abnormalities in Down syndrome?Epigenetic treatment of neurological disease.The role of S100a9 in the pathogenesis of Alzheimer's disease: the therapeutic effects of S100a9 knockdown or knockout.The role of inflammatory processes in Alzheimer's disease.Amyloid-based immunotherapy for Alzheimer's disease in the time of prevention trials: the way forward.The dark sides of amyloid in Alzheimer's disease pathogenesis.Cognitive reserve and Alzheimer's disease.The Long Run: Neuroprotective Effects of Physical Exercise on Adult Neurogenesis from Youth to Old Age.Mechanisms of Melatonin in Alleviating Alzheimer's Disease.Amyloid beta: structure, biology and structure-based therapeutic development.Protein modification by dicarbonyl molecular species in neurodegenerative diseases.Purification and aggregation of the amyloid precursor protein intracellular domain.Amyloid precursor protein: more than just neurodegeneration.In silico-based screen synergistic drug combinations from herb medicines: a case using Cistanche tubulosa.Recent Advances: Decoding Alzheimer's Disease With Stem Cells.Altered neurogenesis in mouse models of Alzheimer disease.Adiponectin Mediates Running-Restored Hippocampal Neurogenesis in Streptozotocin-Induced Type 1 Diabetes in Mice

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APP intracellular domain impairs adult neurogenesis in transgenic mice by inducing neuroinflammation

http://www.wikidata.org/entity/Q27322677

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2010 nî lūn-bûn

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2010 թուականին հրատարակուած գիտական յօդուած

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2010 թվականին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年论文

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name

APP intracellular domain impai ...... by inducing neuroinflammation

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APP intracellular domain impai ...... by inducing neuroinflammation

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APP intracellular domain impai ...... by inducing neuroinflammation

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type

label

APP intracellular domain impai ...... by inducing neuroinflammation

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APP intracellular domain impai ...... by inducing neuroinflammation

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APP intracellular domain impai ...... by inducing neuroinflammation

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prefLabel

APP intracellular domain impai ...... by inducing neuroinflammation

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APP intracellular domain impai ...... by inducing neuroinflammation

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APP intracellular domain impai ...... by inducing neuroinflammation

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APP intracellular domain impai ...... by inducing neuroinflammation

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Andrea Stathopoulos

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Kaushik Ghosal

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Sanjay W Pimplikar

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P2860

The gamma -secretase-cleaved C-terminal fragment of amyloid precursor protein mediates signaling to the nucleus

Allopregnanolone reverses neurogenic and cognitive deficits in mouse model of Alzheimer's disease

Amyloid-beta protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory

The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics

A transcriptionally [correction of transcriptively] active complex of APP with Fe65 and histone acetyltransferase Tip60

Adult neurogenesis, neuroinflammation and therapeutic potential of adult neural stem cells

beta-Amyloid precursor protein-deficient mice show reactive gliosis and decreased locomotor activity

Mechanisms and functional implications of adult neurogenesis

Mechanisms underlying inflammation in neurodegeneration

Functional neurogenesis in the adult hippocampus

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