BIN1 localizes the L-type calcium channel to cardiac T-tubules
about
L-type calcium channel targeting and local signalling in cardiac myocytesCardiomyocyte protein trafficking: Relevance to heart disease and opportunities for therapeutic interventionNa+ channel function, regulation, structure, trafficking and sequestrationDetachment of surface membrane invagination systems by cationic amphiphilic drugsDrosophila Nedd4-long reduces Amphiphysin levels in muscles and leads to impaired T-tubule formation.Ion channel macromolecular complexes in cardiomyocytes: roles in sudden cardiac deathDirect interaction of CaVβ with actin up-regulates L-type calcium currents in HL-1 cardiomyocytesA critical role for Telethonin in regulating t-tubule structure and function in the mammalian heartDisrupted membrane structure and intracellular Ca²⁺ signaling in adult skeletal muscle with acute knockdown of Bin1.Sildenafil ameliorates left ventricular T-tubule remodeling in a pressure overload-induced murine heart failure modelActin cytoskeleton rest stops regulate anterograde traffic of connexin 43 vesicles to the plasma membrane.A micropatterning approach for imaging dynamic Cx43 trafficking to cell-cell borders.Oxidative stress decreases microtubule growth and stability in ventricular myocytesRegulation of Cardiomyocyte T-Tubular Structure: Opportunities for Therapy.Microdomain-specific localization of functional ion channels in cardiomyocytes: an emerging concept of local regulation and remodelling.Cardiac BIN1 folds T-tubule membrane, controlling ion flux and limiting arrhythmia.EHD3-dependent endosome pathway regulates cardiac membrane excitability and physiology.AutoTT: automated detection and analysis of T-tubule architecture in cardiomyocytesAberrant dynamin 2-dependent Na(+) /H(+) exchanger-1 trafficking contributes to cardiomyocyte apoptosis.Cardiac T-Tubule Microanatomy and Function.Intramolecular interactions between the Dbl homology (DH) domain and the carboxyl-terminal region of myosin II-interacting guanine nucleotide exchange factor (MyoGEF) act as an autoinhibitory mechanism for the regulation of MyoGEF functions.Dynasore protects mitochondria and improves cardiac lusitropy in Langendorff perfused mouse heartDependence of cardiac transverse tubules on the BAR domain protein amphiphysin II (BIN-1)The PDZ motif of the α1C subunit is not required for surface trafficking and adrenergic modulation of CaV1.2 channel in the heart.Downregulation of connexin43 by microRNA-130a in cardiomyocytes results in cardiac arrhythmias.Different subcellular populations of L-type Ca2+ channels exhibit unique regulation and functional roles in cardiomyocytesFree Fatty Acid Effects on the Atrial Myocardium: Membrane Ionic Currents Are Remodeled by the Disruption of T-Tubular ArchitectureEps 15 Homology Domain (EHD)-1 Remodels Transverse Tubules in Skeletal Muscle.Targeting cardiomyocyte Ca2+ homeostasis in heart failure.BIN1 is reduced and Cav1.2 trafficking is impaired in human failing cardiomyocytes.Plasma BIN1 correlates with heart failure and predicts arrhythmia in patients with arrhythmogenic right ventricular cardiomyopathy.Mechanical unloading reverses transverse tubule remodelling and normalizes local Ca(2+)-induced Ca(2+)release in a rodent model of heart failureIsoproterenol Promotes Rapid Ryanodine Receptor Movement to Bridging Integrator 1 (BIN1)-Organized Dyads.JPH-2 interacts with Cai-handling proteins and ion channels in dyads: Contribution to premature ventricular contraction-induced cardiomyopathy.The cardiac connexome: Non-canonical functions of connexin43 and their role in cardiac arrhythmias.Spatial control of the βAR system in heart failure: the transverse tubule and beyond.BIN1 regulates dynamic t-tubule membrane.The "tail" of Connexin43: An unexpected journey from alternative translation to trafficking.Functional integrity of the T-tubular system in cardiomyocytes depends on p21-activated kinase 1Plasticity of surface structures and β(2)-adrenergic receptor localization in failing ventricular cardiomyocytes during recovery from heart failure.
P2860
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P2860
BIN1 localizes the L-type calcium channel to cardiac T-tubules
description
2010 nî lūn-bûn
@nan
2010 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
BIN1 localizes the L-type calcium channel to cardiac T-tubules
@ast
BIN1 localizes the L-type calcium channel to cardiac T-tubules
@en
BIN1 localizes the L-type calcium channel to cardiac T-tubules
@nl
type
label
BIN1 localizes the L-type calcium channel to cardiac T-tubules
@ast
BIN1 localizes the L-type calcium channel to cardiac T-tubules
@en
BIN1 localizes the L-type calcium channel to cardiac T-tubules
@nl
prefLabel
BIN1 localizes the L-type calcium channel to cardiac T-tubules
@ast
BIN1 localizes the L-type calcium channel to cardiac T-tubules
@en
BIN1 localizes the L-type calcium channel to cardiac T-tubules
@nl
P2093
P2860
P1433
P1476
BIN1 localizes the L-type calcium channel to cardiac T-tubules
@en
P2093
Brian C Jensen
Danchen Gao
Henry M Colecraft
Jacob M Vogan
Kevin Y Chu
Tina S Fong
Ting-Ting Hong
P2860
P304
P356
10.1371/JOURNAL.PBIO.1000312
P407
P577
2010-02-16T00:00:00Z