Haploinsufficiency of Cyfip1 produces fragile X-like phenotypes in mice
about
The unstable repeats--three evolving faces of neurological diseaseFragile X-like behaviors and abnormal cortical dendritic spines in cytoplasmic FMR1-interacting protein 2-mutant mice.The 15q11.2 BP1-BP2 microdeletion syndrome: a reviewCyfip1 Regulates Presynaptic Activity during DevelopmentThe autism and schizophrenia associated gene CYFIP1 is critical for the maintenance of dendritic complexity and the stabilization of mature spinesCYFIP1 coordinates mRNA translation and cytoskeleton remodeling to ensure proper dendritic spine formationTowards identification of individual etiologies by resolving genomic and biological conundrums in patients with autism spectrum disorders.15q11.2 CNV affects cognitive, structural and functional correlates of dyslexia and dyscalculia.New insights into the regulatory function of CYFIP1 in the context of WAVE- and FMRP-containing complexes.Selected rapporteur summaries from the XX World Congress of Psychiatric Genetics, Hamburg, Germany, October 14-18, 2012.Modeling a genetic risk for schizophrenia in iPSCs and mice reveals neural stem cell deficits associated with adherens junctions and polarity.Increased CYFIP1 dosage alters cellular and dendritic morphology and dysregulates mTORNxf7 deficiency impairs social exploration and spatio-cognitive abilities as well as hippocampal synaptic plasticity in mice.C57BL/6N mutation in cytoplasmic FMRP interacting protein 2 regulates cocaine response.A Common CYFIP1 Variant at the 15q11.2 Disease Locus Is Associated with Structural Variation at the Language-Related Left Supramarginal Gyrus.Autism-Associated Insertion Mutation (InsG) of Shank3 Exon 21 Causes Impaired Synaptic Transmission and Behavioral Deficits.Reduced CYFIP1 in Human Neural Progenitors Results in Dysregulation of Schizophrenia and Epilepsy Gene Networks.Parental origin impairment of synaptic functions and behaviors in cytoplasmic FMRP interacting protein 1 (Cyfip1) deficient miceExperience-induced Arc/Arg3.1 primes CA1 pyramidal neurons for metabotropic glutamate receptor-dependent long-term synaptic depressionNegative Allosteric Modulation of mGluR5 Partially Corrects Pathophysiology in a Mouse Model of Rett Syndrome.CYFIP family proteins between autism and intellectual disability: links with Fragile X syndrome.Recurrent copy number variations as risk factors for neurodevelopmental disorders: critical overview and analysis of clinical implications.Calpains: Master Regulators of Synaptic Plasticity.Perturbed proteostasis in autism spectrum disorders.Common variants in genes of the postsynaptic FMRP signalling pathway are risk factors for autism spectrum disorders.Recurrent 15q11.2 BP1-BP2 microdeletions and microduplications in the etiology of neurodevelopmental disorders.BDNF stimulation of protein synthesis in cortical neurons requires the MAP kinase-interacting kinase MNK1.Clinical and genetic aspects of the 15q11.2 BP1-BP2 microdeletion disorder.Protein synthesis levels are increased in a subset of individuals with Fragile X syndrome.Axon-Axon Interactions Regulate Topographic Optic Tract Sorting via CYFIP2-Dependent WAVE Complex Function.Genetic counseling for susceptibility loci and neurodevelopmental disorders: the del15q11.2 as an example.
P2860
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P2860
Haploinsufficiency of Cyfip1 produces fragile X-like phenotypes in mice
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2012 nî lūn-bûn
@nan
2012 թուականին հրատարակուած գիտական յօդուած
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2012 թվականին հրատարակված գիտական հոդված
@hy
2012年の論文
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2012年論文
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2012年論文
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2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
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name
Haploinsufficiency of Cyfip1 produces fragile X-like phenotypes in mice
@ast
Haploinsufficiency of Cyfip1 produces fragile X-like phenotypes in mice
@en
Haploinsufficiency of Cyfip1 produces fragile X-like phenotypes in mice
@nl
type
label
Haploinsufficiency of Cyfip1 produces fragile X-like phenotypes in mice
@ast
Haploinsufficiency of Cyfip1 produces fragile X-like phenotypes in mice
@en
Haploinsufficiency of Cyfip1 produces fragile X-like phenotypes in mice
@nl
prefLabel
Haploinsufficiency of Cyfip1 produces fragile X-like phenotypes in mice
@ast
Haploinsufficiency of Cyfip1 produces fragile X-like phenotypes in mice
@en
Haploinsufficiency of Cyfip1 produces fragile X-like phenotypes in mice
@nl
P2093
P2860
P3181
P1433
P1476
Haploinsufficiency of Cyfip1 produces fragile X-like phenotypes in mice
@en
P2093
Marion Pilorge
Nagahide Takahashi
Nathan Dorr
Ozlem Bozdagi
Takeshi Sakurai
P2860
P304
P3181
P356
10.1371/JOURNAL.PONE.0042422
P407
P577
2012-01-01T00:00:00Z