Mammalian target of rapamycin is a therapeutic target for murine ovarian endometrioid adenocarcinomas with dysregulated Wnt/β-catenin and PTEN - Test2 - elhamkhani - TriplyDB

Mammalian target of rapamycin is a therapeutic target for murine ovarian endometrioid adenocarcinomas with dysregulated Wnt/β-catenin and PTEN

Mammalian target of rapamycin is a therapeutic target for murine ovarian endometrioid adenocarcinomas with dysregulated Wnt/β-catenin and PTEN

http://www.wikidata.org/entity/Q27335766

about

Medical treatment of early stage and rare histological variants of epithelial ovarian cancer The PI3K/Akt/mTOR pathway in ovarian cancer: therapeutic opportunities and challenges Niclosamide and its analogs are potent inhibitors of Wnt/β-catenin, mTOR and STAT3 signaling in ovarian cancer.Mammalian target of rapamycin complex 1 and cyclooxygenase 2 pathways cooperatively exacerbate endometrial cancer.Stromal liver kinase B1 [STK11] signaling loss induces oviductal adenomas and endometrial cancer by activating mammalian Target of Rapamycin Complex 1.Loss of α-catenin elicits a cholestatic response and impairs liver regeneration.The Müllerian inhibiting substance type 2 receptor suppresses tumorigenesis in testes with sustained β-catenin signaling Arid1a inactivation in an Apc- and Pten-defective mouse ovarian cancer model enhances epithelial differentiation and prolongs survival.Technical challenges and limitations of current mouse models of ovarian cancer.PTEN loss and HOXA10 expression are associated with ovarian endometrioid adenocarcinoma differentiation and progression.Germ cell specific overactivation of WNT/βcatenin signalling has no effect on folliculogenesis but causes fertility defects due to abnormal foetal development Immunobiology of human mucin 1 in a preclinical ovarian tumor model.Loss of LKB1 and PTEN tumor suppressor genes in the ovarian surface epithelium induces papillary serous ovarian cancer.Ovarian hormones through Wnt signalling regulate the growth of human and mouse ovarian cancer initiating lesions Germ cell-specific sustained activation of Wnt signalling perturbs spermatogenesis in aged mice, possibly through non-coding RNAs.Cell growth inhibition and induction of apoptosis by snake venom toxin in ovarian cancer cell via inactivation of nuclear factor κB and signal transducer and activator of transcription 3.Preclinical Models of Ovarian Cancer: Pathogenesis, Problems, and Implications for Prevention.Wnt and Kras signaling-dark siblings in lung cancer.Specific deletion of LKB1/Stk11 in the Müllerian duct mesenchyme drives hyperplasia of the periurethral stroma and tumorigenesis in male mice.Impact of oviductal versus ovarian epithelial cell of origin on ovarian endometrioid carcinoma phenotype in the mouse.PI3K/AKT/mTOR Pathway in Ovarian Cancer Treatment: Are We on the Right Track?Targeted next-generation sequencing of malignant peripheral nerve sheath tumor of the pterygopalatine fossa with intracranial metastatic recurrence.The Endometriotic Tumor Microenvironment in Ovarian Cancer

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P2860

Mammalian target of rapamycin is a therapeutic target for murine ovarian endometrioid adenocarcinomas with dysregulated Wnt/β-catenin and PTEN

http://www.wikidata.org/entity/Q27335766

description

2011 nî lūn-bûn

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2011年論文

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Mammalian target of rapamycin ...... gulated Wnt/β-catenin and PTEN

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Mammalian target of rapamycin ...... gulated Wnt/β-catenin and PTEN

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Mammalian target of rapamycin ...... gulated Wnt/β-catenin and PTEN

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Mammalian target of rapamycin ...... gulated Wnt/β-catenin and PTEN

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Mammalian target of rapamycin ...... gulated Wnt/β-catenin and PTEN

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Mammalian target of rapamycin ...... gulated Wnt/β-catenin and PTEN

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Mammalian target of rapamycin ...... gulated Wnt/β-catenin and PTEN

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Drucilla J Roberts

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LiHua Zhang

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Makoto M Taketo

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Michael D Curley

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Poonam Rani

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Pradeep S Tanwar

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P2860

A Wnt-Axin2-GSK3beta cascade regulates Snail1 activity in breast cancer cells

Intestinal polyposis in mice with a dominant stable mutation of the beta-catenin gene

A biomarker that identifies senescent human cells in culture and in aging skin in vivo

PTEN tumor suppressor regulates p53 protein levels and activity through phosphatase-dependent and -independent mechanisms

Formation of ovarian follicles during fetal development in sheep

Ovarian surface epithelium: biology, endocrinology, and pathology

Upstream and downstream of mTOR

Requirement of Bmpr1a for Müllerian duct regression during male sexual development

Female development in mammals is regulated by Wnt-4 signalling

Tumorigenesis in the multiple intestinal neoplasia mouse: redundancy of negative regulators and specificity of modifiers

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e20715

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scholarly article

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10.1371/JOURNAL.PONE.0020715

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Jose M Teixeira

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