TgCDPK3 regulates calcium-dependent egress of Toxoplasma gondii from host cells
about
Recent insights into apicomplexan parasite egress provide new views to a killThe calcium signaling toolkit of the Apicomplexan parasites Toxoplasma gondii and Plasmodium sppNeospora caninum calcium-dependent protein kinase 1 is an effective drug target for neosporosis therapyPhosphorylation of a Myosin Motor by TgCDPK3 Facilitates Rapid Initiation of Motility during Toxoplasma gondii egressPhosphatidylthreonine and Lipid-Mediated Control of Parasite VirulenceCalcium-dependent phosphorylation alters class XIVa myosin function in the protozoan parasite Toxoplasma gondiiSerum Albumin Stimulates Protein Kinase G-dependent Microneme Secretion in Toxoplasma gondiiPlasma Membrane Association by N-Acylation Governs PKG Function in Toxoplasma gondiiThe Toxoplasma gondii calcium-dependent protein kinase 7 is involved in early steps of parasite division and is crucial for parasite survival.Evaluation of immune responses in mice after DNA immunization with putative Toxoplasma gondii calcium-dependent protein kinase 5.Protective efficacy of Toxoplasma gondii calcium-dependent protein kinase 1 (TgCDPK1) adjuvated with recombinant IL-15 and IL-21 against experimental toxoplasmosis in miceMechanisms of microbial escape from phagocyte killing.Protective immunity against Toxoplasma gondii induced by DNA immunization with the gene encoding a novel vaccine candidate: calcium-dependent protein kinase 3Small-molecule inhibition of a depalmitoylase enhances Toxoplasma host-cell invasion.Plasmodium berghei calcium dependent protein kinase 1 is not required for host cell invasion.Genetic manipulation of the Toxoplasma gondii genome by fosmid recombineering.The apical complex provides a regulated gateway for secretion of invasion factors in Toxoplasma.The calcium-dependent protein kinase 3 of toxoplasma influences basal calcium levels and functions beyond egress as revealed by quantitative phosphoproteome analysisEfficient genome engineering of Toxoplasma gondii using CRISPR/Cas9.Genome-wide expression patterns of calcium-dependent protein kinases in Toxoplasma gondii.Allosteric activation of apicomplexan calcium-dependent protein kinases.Vaccination with Toxoplasma gondii calcium-dependent protein kinase 6 and rhoptry protein 18 encapsulated in poly(lactide-co-glycolide) microspheres induces long-term protective immunity in mice.Lytic Cycle of Toxoplasma gondii: 15 Years Later.Global Analysis of Palmitoylated Proteins in Toxoplasma gondii.An aspartyl protease defines a novel pathway for export of Toxoplasma proteins into the host cell.N-terminal palmitoylation is required for Toxoplasma gondii HSP20 inner membrane complex localization.Analysis of Noncanonical Calcium-Dependent Protein Kinases in Toxoplasma gondii by Targeted Gene Deletion Using CRISPR/Cas9.Functional Characterization of Rhoptry Kinome in the Virulent Toxoplasma gondii RH Strain.Expression of the essential Kinase PfCDPK1 from Plasmodium falciparum in Toxoplasma gondii facilitates the discovery of novel antimalarial drugsDesigning selective inhibitors for calcium-dependent protein kinases in apicomplexans.A central role for phosphatidic acid as a lipid mediator of regulated exocytosis in apicomplexa.Dynamic protein S-palmitoylation mediates parasite life cycle progression and diverse mechanisms of virulence.Proximity labeling of interacting proteins: Application of BioID as a discovery tool.Molecular Signaling Involved in Entry and Exit of Malaria Parasites from Host Erythrocytes.The serine/threonine phosphatases of apicomplexan parasites.TgERK7 is involved in the intracellular proliferation of Toxoplasma gondii.Gliding motility powers invasion and egress in Apicomplexa.Optogenetic monitoring identifies phosphatidylthreonine-regulated calcium homeostasis in Toxoplasma gondii.Optogenetic modulation of an adenylate cyclase in Toxoplasma gondii demonstrates a requirement of the parasite cAMP for host-cell invasion and stage differentiation.Analysis of Ca2+ mediated signaling regulating Toxoplasma infectivity reveals complex relationships between key molecules.
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P2860
TgCDPK3 regulates calcium-dependent egress of Toxoplasma gondii from host cells
description
2012 nî lūn-bûn
@nan
2012 թուականին հրատարակուած գիտական յօդուած
@hyw
2012 թվականին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
TgCDPK3 regulates calcium-dependent egress of Toxoplasma gondii from host cells
@ast
TgCDPK3 regulates calcium-dependent egress of Toxoplasma gondii from host cells
@en
TgCDPK3 regulates calcium-dependent egress of Toxoplasma gondii from host cells
@nl
type
label
TgCDPK3 regulates calcium-dependent egress of Toxoplasma gondii from host cells
@ast
TgCDPK3 regulates calcium-dependent egress of Toxoplasma gondii from host cells
@en
TgCDPK3 regulates calcium-dependent egress of Toxoplasma gondii from host cells
@nl
prefLabel
TgCDPK3 regulates calcium-dependent egress of Toxoplasma gondii from host cells
@ast
TgCDPK3 regulates calcium-dependent egress of Toxoplasma gondii from host cells
@en
TgCDPK3 regulates calcium-dependent egress of Toxoplasma gondii from host cells
@nl
P2093
P2860
P3181
P1433
P1476
TgCDPK3 regulates calcium-dependent egress of Toxoplasma gondii from host cells
@en
P2093
Christopher J Tonkin
James M McCoy
Lachlan Whitehead
P2860
P304
P3181
P356
10.1371/JOURNAL.PPAT.1003066
P407
P577
2012-01-01T00:00:00Z