Cytoprotective Nrf2 pathway is induced in chronically txnrd 1-deficient hepatocytes
about
Interplay between cytosolic disulfide reductase systems and the Nrf2/Keap1 pathwayTrxR1 as a potent regulator of the Nrf2-Keap1 response systemOncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesisBasic principles and emerging concepts in the redox control of transcription factorsParadoxical Roles of Antioxidant Enzymes: Basic Mechanisms and Health ImplicationsMechanisms of activation of the transcription factor Nrf2 by redox stressors, nutrient cues, and energy status and the pathways through which it attenuates degenerative diseaseEmerging roles of Nrf2 and phase II antioxidant enzymes in neuroprotectionThe effects of chromium(VI) on the thioredoxin system: implications for redox regulationChemoprevention of oxidative stress-associated oral carcinogenesis by sulforaphane depends on NRF2 and the isothiocyanate moietySec-containing TrxR1 is essential for self-sufficiency of cells by control of glucose-derived H2O2.Acetaminophen reactive intermediates target hepatic thioredoxin reductaseHepatocytes lacking thioredoxin reductase 1 have normal replicative potential during development and regeneration.Ginger compound [6]-shogaol and its cysteine-conjugated metabolite (M2) activate Nrf2 in colon epithelial cells in vitro and in vivoThe thioredoxin system in neonatal lung diseaseHydrodynamic delivery of Cre protein to lineage-mark or time-stamp mouse hepatocytes in situ.Contributions of new hepatocyte lineages to liver growth, maintenance, and regeneration in mice.Striking differences between knockout and wild-type mice in global gene expression variabilityDietary methionine can sustain cytosolic redox homeostasis in the mouse liver.Dual fluorescent reporter pig for Cre recombination: transgene placement at the ROSA26 locusThe 15kDa selenoprotein and thioredoxin reductase 1 promote colon cancer by different pathwaysExpression of Selenoproteins Is Maintained in Mice Carrying Mutations in SECp43, the tRNA Selenocysteine 1 Associated Protein (Trnau1ap).Hepatocyte DNA replication in growing liver requires either glutathione or a single allele of txnrd1.Dimethyl Fumarate Protects Neural Stem/Progenitor Cells and Neurons from Oxidative Damage through Nrf2-ERK1/2 MAPK PathwayThioredoxin reductase inhibition elicits Nrf2-mediated responses in Clara cells: implications for oxidant-induced lung injuryDifferences in Redox Regulatory Systems in Human Lung and Liver Tumors Suggest Different Avenues for TherapyThioredoxin reductase 1 deficiency enhances selenite toxicity in cancer cells via a thioredoxin-independent mechanismThioredoxin reductase 1 protects against chemically induced hepatocarcinogenesis via control of cellular redox homeostasis.Compartment-specific Control of Reactive Oxygen Species Scavenging by Antioxidant Pathway Enzymes.Glutathione peroxidase 4 and vitamin E cooperatively prevent hepatocellular degenerationAmniotic fluid activates the nrf2/keap1 pathway to repair an epidermal barrier defect in utero.Selective activation of oxidized PTP1B by the thioredoxin system modulates PDGF-β receptor tyrosine kinase signaling.Selenophosphate synthetase 1 is an essential protein with roles in regulation of redox homoeostasis in mammals.APR-246/PRIMA-1MET inhibits thioredoxin reductase 1 and converts the enzyme to a dedicated NADPH oxidaseNuclear double-fluorescent reporter for in vivo and ex vivo analyses of biological transitions in mouse nuclei.Nrf2 regulates cellular behaviors and Notch signaling in oral squamous cell carcinoma cells.Thioredoxin Reductase Inhibition Attenuates Neonatal Hyperoxic Lung Injury and Enhances Nuclear Factor E2-Related Factor 2 Activation.Thiophosphate and selenite conversely modulate cell death induced by glutathione depletion or cisplatin: effects related to activity and Sec contents of thioredoxin reductase.Nrf2 target genes are induced under marginal selenium-deficiency.The yin and yang of nrf2-regulated selenoproteins in carcinogenesis.A Txnrd1-dependent metabolic switch alters hepatic lipogenesis, glycogen storage, and detoxification.
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P2860
Cytoprotective Nrf2 pathway is induced in chronically txnrd 1-deficient hepatocytes
description
2009 nî lūn-bûn
@nan
2009 թուականին հրատարակուած գիտական յօդուած
@hyw
2009 թվականին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Cytoprotective Nrf2 pathway is induced in chronically txnrd 1-deficient hepatocytes
@ast
Cytoprotective Nrf2 pathway is induced in chronically txnrd 1-deficient hepatocytes
@en
Cytoprotective Nrf2 pathway is induced in chronically txnrd 1-deficient hepatocytes
@nl
type
label
Cytoprotective Nrf2 pathway is induced in chronically txnrd 1-deficient hepatocytes
@ast
Cytoprotective Nrf2 pathway is induced in chronically txnrd 1-deficient hepatocytes
@en
Cytoprotective Nrf2 pathway is induced in chronically txnrd 1-deficient hepatocytes
@nl
prefLabel
Cytoprotective Nrf2 pathway is induced in chronically txnrd 1-deficient hepatocytes
@ast
Cytoprotective Nrf2 pathway is induced in chronically txnrd 1-deficient hepatocytes
@en
Cytoprotective Nrf2 pathway is induced in chronically txnrd 1-deficient hepatocytes
@nl
P2093
P2860
P3181
P1433
P1476
Cytoprotective Nrf2 pathway is induced in chronically txnrd 1-deficient hepatocytes
@en
P2093
Carla M Weisend
Edward E Schmidt
Elena S Suvorova
Gary F Merrill
Mario R Capecchi
Maryclare F Rollins
Olivier Lucas
P2860
P3181
P356
10.1371/JOURNAL.PONE.0006158
P407
P577
2009-01-01T00:00:00Z