An RNA cap (nucleoside-2'-O-)-methyltransferase in the flavivirus RNA polymerase NS5: crystal structure and functional characterization - Test2 - elhamkhani - TriplyDB

An RNA cap (nucleoside-2'-O-)-methyltransferase in the flavivirus RNA polymerase NS5: crystal structure and functional characterization

An RNA cap (nucleoside-2'-O-)-methyltransferase in the flavivirus RNA polymerase NS5: crystal structure and functional characterization

http://www.wikidata.org/entity/Q27472613

about

Discovery of the first insect nidovirus, a missing evolutionary link in the emergence of the largest RNA virus genomes Analysis of RNA binding by the dengue virus NS5 RNA capping enzyme Molecular targets for flavivirus drug discovery A 5' RNA element promotes dengue virus RNA synthesis on a circular genome Specific requirements for elements of the 5' and 3' terminal regions in flavivirus RNA synthesis and viral replication Identification of a novel antiviral inhibitor of the flavivirus guanylyltransferase enzyme The role of viral persistence in flavivirus biology Structure and functionality in flavivirus NS-proteins: perspectives for drug design Conservation and variability of dengue virus proteins: implications for vaccine design Structural and Functional Analyses of a Conserved Hydrophobic Pocket of Flavivirus Methyltransferase Dengue virus utilizes a novel strategy for translation initiation when cap-dependent translation is inhibited Enzymology of RNA cap synthesis Innate immunity evasion by Dengue virus Structural proteomics of dengue virus Potent Allosteric Dengue Virus NS5 Polymerase Inhibitors: Mechanism of Action and Resistance Profiling Inhibitor designing, virtual screening, and docking studies for methyltransferase: A potential target against dengue virus Flaviviral NS4b, chameleon and jack-in-the-box roles in viral replication and pathogenesis, and a molecular target for antiviral intervention Functions of the 3' and 5' genome RNA regions of members of the genus Flavivirus Flaviviral Replication Complex: Coordination between RNA Synthesis and 5'-RNA Capping The Dengue Virus NS5 Protein Intrudes in the Cellular Spliceosome and Modulates Splicing Common and unique features of viral RNA-dependent polymerases Japanese encephalitis: the virus and vaccines Viral RNA switch mediates the dynamic control of flavivirus replicase recruitment by genome cyclization Live Cell Analysis and Mathematical Modeling Identify Determinants of Attenuation of Dengue Virus 2'-O-Methylation Mutant A crystal structure of the Dengue virus NS5 protein reveals a novel inter-domain interface essential for protein flexibility and virus replication Rational design of a live attenuated dengue vaccine: 2'-o-methyltransferase mutants are highly attenuated and immunogenic in mice and macaques Virtual Screening for Potential Inhibitors of NS3 Protein of Zika Virus The C-terminal 18 Amino Acid Region of Dengue Virus NS5 Regulates its Subcellular Localization and Contains a Conserved Arginine Residue Essential for Infectious Virus Production Analysis of genotype diversity and evolution of Dengue virus serotype 2 using complete genomes Inhibition of interferon-stimulated JAK-STAT signaling by a tick-borne flavivirus and identification of NS5 as an interferon antagonist Role for nsP2 proteins in the cessation of alphavirus minus-strand synthesis by host cells A tick-borne Langat virus mutant that is temperature sensitive and host range restricted in neuroblastoma cells and lacks neuroinvasiveness for immunodeficient mice Triaryl pyrazoline compound inhibits flavivirus RNA replication.Blocking of Interferon-Induced Jak-Stat Signaling by Japanese Encephalitis Virus NS5 through a Protein Tyrosine Phosphatase-Mediated Mechanism Autographa californica Nucleopolyhedrovirus orf69 Encodes an RNA Cap (Nucleoside-2'-O)-Methyltransferase West Nile Virus 5'-Cap Structure Is Formed by Sequential Guanine N-7 and Ribose 2'-O Methylations by Nonstructural Protein 5 Pathogenesis of West Nile Virus Infection: a Balance between Virulence, Innate and Adaptive Immunity, and Viral Evasion Functional characterization of a 48 kDa Trypanosoma brucei cap 2 RNA methyltransferase Recent Advances in Deciphering Viral and Host Determinants of Dengue Virus Replication and Pathogenesis De Novo Synthesis of Negative-Strand RNA by Dengue Virus RNA-Dependent RNA Polymerase In Vitro: Nucleotide, Primer, and Template Parameters

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P2860

An RNA cap (nucleoside-2'-O-)-methyltransferase in the flavivirus RNA polymerase NS5: crystal structure and functional characterization

http://www.wikidata.org/entity/Q27472613

description

2002 nî lūn-bûn

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2002年の論文

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An RNA cap (nucleoside-2'-O-)- ...... nd functional characterization

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An RNA cap (nucleoside-2'-O-)- ...... nd functional characterization

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An RNA cap (nucleoside-2'-O-)- ...... nd functional characterization

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An RNA cap (nucleoside-2'-O-)- ...... nd functional characterization

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An RNA cap (nucleoside-2'-O-)- ...... nd functional characterization

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The EMBO Journal

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An RNA cap (nucleoside-2'-O-)- ...... nd functional characterization

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Barbara Selisko

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Delphine Benarroch

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Marie-Pierre Egloff

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P2860

CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice

Flavivirus genome organization, expression, and replication

mRNA:guanine-N7 cap methyltransferases: identification of novel members of the family, evolutionary analysis, homology modeling, and analysis of sequence-structure-function relationships

Reassignment of specificities of two cap methyltransferase domains in the reovirus lambda 2 protein

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

Morphologic and Molecular Characterization of New Cyclospora Species from Ethiopian Monkeys: C. cercopitheci sp.n., C. colobi sp.n., and C. papionis sp.n

Isolation of Two Strains of West Nile Virus during an Outbreak in Southern Russia, 1999

mRNA cap recognition: dominant role of enhanced stacking interactions between methylated bases and protein aromatic side chains

Three-dimensional structure of adenosylcobinamide kinase/adenosylcobinamide phosphate guanylyltransferase (CobU) complexed with GMP: evidence for a substrate-induced transferase active site

Structure and mechanism of yeast RNA triphosphatase: an essential component of the mRNA capping apparatus

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319421

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10.1093/EMBOJ/21.11.2757

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11

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21

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Barbara Selisko

Jean-Louis Romette

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2002-06-03T00:00:00Z

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11340604

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12032088

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crystal structure

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125380

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