The CD81 Partner EWI-2wint Inhibits Hepatitis C Virus Entry - Test2 - elhamkhani - TriplyDB

The CD81 Partner EWI-2wint Inhibits Hepatitis C Virus Entry

The CD81 Partner EWI-2wint Inhibits Hepatitis C Virus Entry

http://www.wikidata.org/entity/Q27485588

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Structural basis of ligand interactions of the large extracellular domain of tetraspanin CD81 Identification of a novel drug lead that inhibits HCV infection and cell-to-cell transmission by targeting the HCV E2 glycoprotein Decoding protein networks during virus entry by quantitative proteomics Gene expression and hepatitis C virus infection The association of CD81 with tetraspanin-enriched microdomains is not essential for Hepatitis C virus entry Identification of GBF1 as a Cellular Factor Required for Hepatitis C Virus RNA Replication Plasmodium falciparum inhibitor-3 homolog increases protein phosphatase type 1 activity and is essential for parasitic survival Hepatitis C virus replication and Golgi function in brefeldin a-resistant hepatoma-derived cells Claudin association with CD81 defines hepatitis C virus entry.Fusogenic properties of the ectodomains of hepatitis C virus envelope proteins.Reducing agents affect inhibitory activities of compounds: results from multiple drug targets.The Ig domain protein CD9P-1 down-regulates CD81 ability to support Plasmodium yoelii infection A Sequence in the loop domain of hepatitis C virus E2 protein identified in silico as crucial for the selective binding to human CD81.Viruses and tetraspanins: lessons from single molecule approaches.NS2 protein of hepatitis C virus interacts with structural and non-structural proteins towards virus assembly.Completion of hepatitis C virus replication cycle in heterokaryons excludes dominant restrictions in human non-liver and mouse liver cell lines.The extracellular δ-domain is essential for the formation of CD81 tetraspanin webs.Role of N-linked glycans in the functions of hepatitis C virus envelope proteins incorporated into infectious virions.The level of Ets-1 protein is regulated by poly(ADP-ribose) polymerase-1 (PARP-1) in cancer cells to prevent DNA damage.Complex N-linked glycans serve as a determinant for exosome/microvesicle cargo recruitment.Discovery of cellular proteins required for the early steps of HCV infection using integrative genomics.Interacting regions of CD81 and two of its partners, EWI-2 and EWI-2wint, and their effect on hepatitis C virus infection An overview of HCV molecular biology, replication and immune responses.Lateral organization of membrane proteins: tetraspanins spin their web.EWI-2 negatively regulates TGF-β signaling leading to altered melanoma growth and metastasis.Hepatitis C virus is primed by CD81 protein for low pH-dependent fusion Claudin-6 and Occludin Natural Variants Found in a Patient Highly Exposed but Not Infected with Hepatitis C Virus (HCV) Do Not Confer HCV Resistance In Vitro.Hepatitis C virus host cell entry.New Insights into the Understanding of Hepatitis C Virus Entry and Cell-to-Cell Transmission by Using the Ionophore Monensin A.Hepatitis C Virus Envelope Glycoprotein E1 Forms Trimers at the Surface of the Virion.Hepatitis C virus has a genetically determined lymphotropism through co-receptor B7.2.Targeting of tetraspanin proteins--potential benefits and strategies Identification of a New Benzimidazole Derivative as an Antiviral against Hepatitis C Virus Cellular and molecular biology of HCV infection and hepatitis.The hepatitis C virus and its hepatic environment: a toxic but finely tuned partnership.CD81 and hepatitis C virus (HCV) infection.How hepatitis C virus invades hepatocytes: the mystery of viral entry Hepatitis C: viral and host factors associated with non-response to pegylated interferon plus ribavirin.Hepatitis C virus entry and the tetraspanin CD81.Recent advances in hepatitis C virus cell entry.

P2860

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P2860

The CD81 Partner EWI-2wint Inhibits Hepatitis C Virus Entry

http://www.wikidata.org/entity/Q27485588

description

2008 nî lūn-bûn

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2008 թուականի Ապրիլին հրատարակուած գիտական յօդուած

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2008 թվականի ապրիլին հրատարակված գիտական հոդված

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2008年の論文

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2008年学术文章

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2008年学术文章

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2008年学术文章

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2008年学术文章

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2008年学术文章

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2008年學術文章

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name

The CD81 Partner EWI-2wint Inhibits Hepatitis C Virus Entry

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The CD81 Partner EWI-2wint Inhibits Hepatitis C Virus Entry

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The CD81 Partner EWI-2wint Inhibits Hepatitis C Virus Entry

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The CD81 Partner EWI-2wint Inhibits Hepatitis C Virus Entry

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The CD81 Partner EWI-2wint Inhibits Hepatitis C Virus Entry

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The CD81 Partner EWI-2wint Inhibits Hepatitis C Virus Entry

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The CD81 Partner EWI-2wint Inhibits Hepatitis C Virus Entry

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The CD81 Partner EWI-2wint Inhibits Hepatitis C Virus Entry

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The CD81 Partner EWI-2wint Inhibits Hepatitis C Virus Entry

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The CD81 partner EWI-2wint inhibits hepatitis C virus entry

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André Pillez

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Czeslaw Wychowski

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David Delgrange

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François Le Naour

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Shoshana Levy

http://www.w3.org/2001/XMLSchema#string

P2860

Characterization of hepatitis C virus E2 glycoprotein interaction with a putative cellular receptor, CD81.

The major CD9 and CD81 molecular partner. Identification and characterization of the complexes

EWI-2 is a major CD9 and CD81 partner and member of a novel Ig protein subfamily

TAPA-1, the target of an antiproliferative antibody, defines a new family of transmembrane proteins

Identification of amino acid residues in CD81 critical for interaction with hepatitis C virus envelope glycoprotein E2.

EWI-2 is a new component of the tetraspanin web in hepatocytes and lymphoid cells

The tight junction proteins claudin-1, -6, and -9 are entry cofactors for hepatitis C virus

EWI-2 regulates alpha3beta1 integrin-dependent cell functions on laminin-5

Infectious hepatitis C virus pseudo-particles containing functional E1-E2 envelope protein complexes

Initiation of hepatitis C virus infection is dependent on cholesterol and cooperativity between CD81 and scavenger receptor B type I

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scholarly article

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10.1371/JOURNAL.PONE.0001866

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4

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3

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Eric Rubinstein

Claire Montpellier

Stéphanie Charrin

Vera Rocha-Perugini

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2008-04-02T00:00:00Z

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5469356

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18382656

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2270906

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