A Conserved Proline between Domains II and III of Hepatitis C Virus NS5A Influences both RNA Replication and Virus Assembly
about
Hepatitis C virus NS5A inhibits mixed lineage kinase 3 to block apoptosisHepatitis C virus NS5A protein interacts with phosphatidylinositol 4-kinase type IIIalpha and regulates viral propagationThe promiscuous binding of the Fyn SH3 domain to a peptide from the NS5A proteinVinexin β Interacts with Hepatitis C Virus NS5A, Modulating Its Hyperphosphorylation To Regulate Viral Propagation.Hepatitis C virus NS5A protein blocks epidermal growth factor receptor degradation via a proline motif- dependent interactionA major determinant of cyclophilin dependence and cyclosporine susceptibility of hepatitis C virus identified by a genetic approachEnhanced hepatitis C virus genome replication and lipid accumulation mediated by inhibition of AMP-activated protein kinaseHepatitis C virus NS5A activates the mammalian target of rapamycin (mTOR) pathway, contributing to cell survival by disrupting the interaction between FK506-binding protein 38 (FKBP38) and mTORExpanding the proteome of an RNA virus by phosphorylation of an intrinsically disordered viral protein.Sequence heterogeneity in NS5A of hepatitis C virus genotypes 2a and 2b and clinical outcome of pegylated-interferon/ribavirin therapyAnalysis of functional differences between hepatitis C virus NS5A of genotypes 1-7 in infectious cell culture systems.A cell culture adapted HCV JFH1 variant that increases viral titers and permits the production of high titer infectious chimeric reporter viruses.The subcellular localization of the hepatitis C virus non-structural protein NS2 is regulated by an ion channel-independent function of the p7 proteinCharged residues in hepatitis C virus NS4B are critical for multiple NS4B functions in RNA replication.A hepatitis C virus NS5A phosphorylation site that regulates RNA replication.The C terminus of NS5A domain II is a key determinant of hepatitis C virus genome replication, but is not required for virion assembly and release.ISG12a Restricts Hepatitis C Virus Infection through the Ubiquitination-Dependent Degradation Pathway.Impact of hepatitis C virus heterogeneity on interferon sensitivity: an overview.Functional characterization of bovine viral diarrhea virus nonstructural protein 5A by reverse genetic analysis and live cell imaging.A conserved tandem cyclophilin-binding site in hepatitis C virus nonstructural protein 5A regulates Alisporivir susceptibility.Resistance mutations define specific antiviral effects for inhibitors of the hepatitis C virus p7 ion channel.Prediction of response to pegylated interferon/ribavirin combination therapy for chronic hepatitis C genotype 1b and high viral load.A role for domain I of the hepatitis C virus NS5A protein in virus assembly.HCV NS5A dimer interface residues regulate HCV replication by controlling its self-interaction, hyperphosphorylation, subcellular localization and interaction with cyclophilin A
P2860
Q24308485-2262B5C0-1F27-4FA0-ACF0-AE1FA6896C89Q24339370-B1894974-06F2-4945-8A93-7506B663085DQ27681909-216B3D5E-6D76-434B-978B-984F55ECDC76Q30009166-88740D5B-007A-4153-8A8F-027F9D0E0A98Q30009188-A912E502-7DD3-4D37-B951-8ECC3D3CFB3AQ33707739-E04A1BC6-8DF6-40B9-888D-2DD9EAFAB599Q33953064-C8AB6E78-D3E2-4812-A567-144CB6D08F0EQ33966987-C54A2CA0-6B67-49BC-A62A-4485FE5E2270Q34107289-DBD5D1C7-9FA9-4556-8442-B49DE3DA3B06Q34154593-57015032-FA9C-4899-AF4B-E115C06B76D7Q34288777-B5B169E2-32B7-4D44-A9BE-AFFB06E8E964Q34427768-FB8D87A2-A03A-43DE-BB68-6C9EAB80C333Q35097566-6FE290C0-DCB4-4A09-942C-5CCBF142BB1FQ35140442-8C643A96-E8C6-483F-A9D2-B0686D3416EAQ36559512-2B8B68B1-C09E-4923-BA96-FB6A80D6869FQ37006634-5A1395C4-8701-4859-BE56-004934F90792Q37093500-95B1749C-2715-4FE8-BD45-7CA6961E97B7Q38224436-02045E13-DF6B-4475-8E38-D088857AE7B7Q38311888-A20E5490-CC53-44BB-BAEA-2502D41F7146Q39394432-464380D7-9482-460A-B161-B5A6DBC41646Q39552847-F29A62DC-CD87-4BED-83C2-74603C876A17Q42978648-9E519A4B-5ABD-428D-9DB6-53E26ADB540AQ47551049-D6805AB5-1FA0-4650-A00D-675FF56C208EQ56396163-1B46561B-A31F-44BC-AF3A-877F33CE8868
P2860
A Conserved Proline between Domains II and III of Hepatitis C Virus NS5A Influences both RNA Replication and Virus Assembly
description
2009 nî lūn-bûn
@nan
2009 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
A Conserved Proline between Do ...... Replication and Virus Assembly
@ast
A Conserved Proline between Do ...... Replication and Virus Assembly
@en
A Conserved Proline between Do ...... Replication and Virus Assembly
@en-gb
A Conserved Proline between Do ...... Replication and Virus Assembly
@nl
type
label
A Conserved Proline between Do ...... Replication and Virus Assembly
@ast
A Conserved Proline between Do ...... Replication and Virus Assembly
@en
A Conserved Proline between Do ...... Replication and Virus Assembly
@en-gb
A Conserved Proline between Do ...... Replication and Virus Assembly
@nl
prefLabel
A Conserved Proline between Do ...... Replication and Virus Assembly
@ast
A Conserved Proline between Do ...... Replication and Virus Assembly
@en
A Conserved Proline between Do ...... Replication and Virus Assembly
@en-gb
A Conserved Proline between Do ...... Replication and Virus Assembly
@nl
P2093
P2860
P50
P356
P1433
P1476
A Conserved Proline between Do ...... Replication and Virus Assembly
@en
P2093
Allan G N Angus
Arvind H Patel
David D Brown
Mair Hughes
Sarah Gretton
P2860
P304
P356
10.1128/JVI.02406-08
P577
2009-10-01T00:00:00Z