Identification and Characterization of Broadly Neutralizing Human Monoclonal Antibodies Directed against the E2 Envelope Glycoprotein of Hepatitis C Virus - Test2 - elhamkhani - TriplyDB

Identification and Characterization of Broadly Neutralizing Human Monoclonal Antibodies Directed against the E2 Envelope Glycoprotein of Hepatitis C Virus

Identification and Characterization of Broadly Neutralizing Human Monoclonal Antibodies Directed against the E2 Envelope Glycoprotein of Hepatitis C Virus

http://www.wikidata.org/entity/Q27490467

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Monoclonal antibodies: Principles and applications of immmunodiagnosis and immunotherapy for hepatitis C virus Genetic Diversity Underlying the Envelope Glycoproteins of Hepatitis C Virus: Structural and Functional Consequences and the Implications for Vaccine Design A high-throughput shotgun mutagenesis approach to mapping B-cell antibody epitopes The hepatitis C virus glycan shield and evasion of the humoral immune response Neutralizing antibody response to hepatitis C virus Bivalent vaccine platform based on Japanese encephalitis virus (JEV) elicits neutralizing antibodies against JEV and hepatitis C virus Structure of Hepatitis C Virus Envelope Glycoprotein E2 Antigenic Site 412 to 423 in Complex with Antibody AP33 Toward a Hepatitis C Virus Vaccine: the Structural Basis of Hepatitis C Virus Neutralization by AP33, a Broadly Neutralizing Antibody Structural basis of hepatitis C virus neutralization by broadly neutralizing antibody HCV1 Hepatitis C Virus E2 Envelope Glycoprotein Core Structure A novel small molecule inhibitor of hepatitis C virus entry Human monoclonal antibodies to a novel cluster of conformational epitopes on HCV E2 with resistance to neutralization escape in a genotype 2a isolate Human monoclonal antibody HCV1 effectively prevents and treats HCV infection in chimpanzees Capitalizing on knowledge of hepatitis C virus neutralizing epitopes for rational vaccine design A Hepatitis C Virus Envelope Polymorphism Confers Resistance to Neutralization by Polyclonal Sera and Broadly Neutralizing Monoclonal Antibodies Optimization of peptide arrays for studying antibodies to hepatitis C virus continuous epitopes.Clearance of hepatitis C infection is associated with the early appearance of broad neutralizing antibody responses Mutations within a conserved region of the hepatitis C virus E2 glycoprotein that influence virus-receptor interactions and sensitivity to neutralizing antibodies.Non-random escape pathways from a broadly neutralizing human monoclonal antibody map to a highly conserved region on the hepatitis C virus E2 glycoprotein encompassing amino acids 412-423 Human broadly neutralizing antibodies to the envelope glycoprotein complex of hepatitis C virus Hepatitis C virus experimental model systems and antiviral drug research.Fine mapping of murine antibody responses to immunization with a novel soluble form of hepatitis C virus envelope glycoprotein complex.Exosomes from hepatitis C infected patients transmit HCV infection and contain replication competent viral RNA in complex with Ago2-miR122-HSP90.Designing and Development of a DNA Vaccine Based On Structural Proteins of Hepatitis C Virus Potential treatment options and future research to increase hepatitis C virus treatment response rate Isolation of human monoclonal antibodies to the envelope e2 protein of hepatitis C virus and their characterization.Analysis of the evolution and structure of a complex intrahost viral population in chronic hepatitis C virus mapped by ultradeep pyrosequencing.Identification of human monoclonal antibodies specific for human SOD1 recognizing distinct epitopes and forms of SOD1.In vivo evaluation of the cross-genotype neutralizing activity of polyclonal antibodies against hepatitis C virus.Fast track antibody V-gene rescue, recombinant expression in plants and characterization of a PfMSP4-specific antibody.High-throughput sequencing analysis of post-liver transplantation HCV E2 glycoprotein evolution in the presence and absence of neutralizing monoclonal antibody.Naturally selected hepatitis C virus polymorphisms confer broad neutralizing antibody resistance.Structural basis for penetration of the glycan shield of hepatitis C virus E2 glycoprotein by a broadly neutralizing human antibody.Inhibition of HCV 3a genotype entry through host CD81 and HCV E2 antibodies Longitudinal Sequence and Functional Evolution within Glycoprotein E2 in Hepatitis C Virus Genotype 3a Infection A systematic analysis of a broadly neutralizing antibody AR3C epitopes on Hepatitis C virus E2 envelope glycoprotein and their cross-reactivity Approaching rational epitope vaccine design for hepatitis C virus with meta-server and multivalent scaffolding Applying antibody-sensitive hypervariable region 1-deleted hepatitis C virus to the study of escape pathways of neutralizing human monoclonal antibody AR5A.Extra-epitopic hepatitis C virus polymorphisms confer resistance to broadly neutralizing antibodies by modulating binding to scavenger receptor B1 Monoclonal Antibodies Directed toward the Hepatitis C Virus Glycoprotein E2 Detect Antigenic Differences Modulated by the N-Terminal Hypervariable Region 1 (HVR1), HVR2, and Intergenotypic Variable Region

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Identification and Characterization of Broadly Neutralizing Human Monoclonal Antibodies Directed against the E2 Envelope Glycoprotein of Hepatitis C Virus

http://www.wikidata.org/entity/Q27490467

description

2009 nî lūn-bûn

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2009 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2009 թվականի դեկտեմբերին հրատարակված գիտական հոդված

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2009年の論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年论文

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Identification and Characteriz ...... coprotein of Hepatitis C Virus

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Identification and Characteriz ...... coprotein of Hepatitis C Virus

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Identification and Characteriz ...... coprotein of Hepatitis C Virus

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Identification and Characteriz ...... coprotein of Hepatitis C Virus

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Identification and Characteriz ...... coprotein of Hepatitis C Virus

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Identification and Characteriz ...... coprotein of Hepatitis C Virus

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Identification and Characteriz ...... coprotein of Hepatitis C Virus

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Identification and Characteriz ...... coprotein of Hepatitis C Virus

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Identification and Characteriz ...... coprotein of Hepatitis C Virus

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Identification and Characteriz ...... coprotein of Hepatitis C Virus

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Donna M Ambrosino

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Frantisek Sandor

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Gregory J Babcock

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Gyongyi Szabo

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Kerry A Garrity

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Naomi K Boatright

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Robert W Finberg

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Susan E Sloan

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Teresa J Broering

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William D Thomas

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P2860

Binding of hepatitis C virus to CD81

Characterization of hepatitis C virus E2 glycoprotein interaction with a putative cellular receptor, CD81.

The human scavenger receptor class B type I is a novel candidate receptor for the hepatitis C virus.

Infectious hepatitis C virus pseudo-particles containing functional E1-E2 envelope protein complexes

Human immunodeficiency virus type 1 viral protein R (Vpr) arrests cells in the G2 phase of the cell cycle by inhibiting p34cdc2 activity

Human monoclonal antibodies that inhibit binding of hepatitis C virus E2 protein to CD81 and recognize conserved conformational epitopes

Mapping B-cell epitopes of hepatitis C virus E2 glycoprotein using human monoclonal antibodies from phage display libraries

Monoclonal Antibody AP33 Defines a Broadly Neutralizing Epitope on the Hepatitis C Virus E2 Envelope Glycoprotein

Identification of Conserved Residues in the E2 Envelope Glycoprotein of the Hepatitis C Virus That Are Critical for CD81 Binding

Hepatitis C virus glycoproteins mediate pH-dependent cell entry of pseudotyped retroviral particles

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12473-82

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scholarly article

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1296223

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10.1128/JVI.01138-09

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23

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83

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2009-12-01T00:00:00Z

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19759151

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2786766

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