about
Three decades of beta-lactamase inhibitorsSulbactam forms only minimal amounts of irreversible acrylate-enzyme with SHV-1 beta-lactamaseAcyl-intermediate structures of the extended-spectrum class A beta-lactamase, Toho-1, in complex with cefotaxime, cephalothin, and benzylpenicillinInhibition of Class A β-Lactamases by Carbapenems: Crystallographic Observation of Two Conformations of Meropenem in SHV-1Novel Insights into the Mode of Inhibition of Class A SHV-1 -Lactamases Revealed by Boronic Acid Transition State InhibitorsLigand-Dependent Disorder of the Loop Observed in Extended-Spectrum SHV-Type -LactamaseAnalysis of the Binding Forces Driving the Tight Interactions between -Lactamase Inhibitory Protein-II (BLIP-II) and Class A -LactamasesThe Importance of thetrans-Enamine Intermediate as a β-Lactamase Inhibition Strategy Probed in Inhibitor-Resistant SHV β-Lactamase VariantsCan Inhibitor-Resistant Substitutions in the Mycobacterium tuberculosis -Lactamase BlaC Lead to Clavulanate Resistance?: a Biochemical Rationale for the Use of -Lactam- -Lactamase Inhibitor CombinationsPenam Sulfones and β-Lactamase Inhibition: SA2-13 and the Importance of the C2 Side Chain Length and CompositionStructural and mechanistic studies of the orf12 gene product from the clavulanic acid biosynthesis pathwayStructural basis for carbapenem-hydrolyzing mechanisms of carbapenemases conferring antibiotic resistanceExploring the role of a conserved class A residue in the Ω-Loop of KPC-2 β-lactamase: a mechanism for ceftazidime hydrolysisDiversity and evolution of the class A chromosomal beta-lactamase gene in Klebsiella pneumoniae.Tazobactam inactivation of SHV-1 and the inhibitor-resistant Ser130 -->Gly SHV-1 beta-lactamase: insights into the mechanism of inhibition.Different intermediate populations formed by tazobactam, sulbactam, and clavulanate reacting with SHV-1 beta-lactamases: Raman crystallographic evidenceIdentification and characterization of beta-lactamase inhibitor protein-II (BLIP-II) interactions with beta-lactamases using phage display.Enhancing resistance to cephalosporins in class C beta-lactamases: impact of Gly214Glu in CMY-2.The role of a second-shell residue in modifying substrate and inhibitor interactions in the SHV beta-lactamase: a study of ambler position Asn276.SHV Lactamase Engineering Database: a reconciliation tool for SHV β-lactamases in public databases.A new SHV-derived extended-spectrum beta-lactamase (SHV-24) that hydrolyzes ceftazidime through a single-amino-acid substitution (D179G) in the -loop.SHV-16, a beta-lactamase with a pentapeptide duplication in the omega loop.Amino acid substitutions at Ambler position Gly238 in the SHV-1 beta-lactamase: exploring sequence requirements for resistance to penicillins and cephalosporins.Prediction of the evolution of ceftazidime resistance in extended-spectrum beta-lactamase CTX-M-9.Structural consequences of the inhibitor-resistant Ser130Gly substitution in TEM beta-lactamaseAn analysis of why highly similar enzymes evolve differentlyVariations within class-A β-lactamase physiochemical properties reflect evolutionary and environmental patterns, but not antibiotic specificityRole of SHV β-lactamase variants in resistance of clinical Klebsiella pneumoniae strains to β-lactams in an Algerian hospital.Role of Asp104 in the SHV beta-lactamase.A new TEM-derived extended-spectrum beta-lactamase (TEM-91) with an R164C substitution at the omega-loop confers ceftazidime resistanceCharacterization of the inhibitor-resistant SHV β-lactamase SHV-107 in a clinical Klebsiella pneumoniae strain coproducing GES-7 enzyme.Activity of ceftazidime/avibactam against isogenic strains of Escherichia coli containing KPC and SHV β-lactamases with single amino acid substitutions in the Ω-loop.Beta-lactamase inhibitors: evolving compounds for evolving resistance targets.The Lys234Arg substitution in the enzyme SHV-72 is a determinant for resistance to clavulanic acid inhibition.A Structure-Based Classification of Class A β-Lactamases, a Broadly Diverse Family of Enzymes.Crystal Structures of KPC-2 and SHV-1 β-Lactamases in Complex with the Boronic Acid Transition State Analog S02030SHV-129: A Gateway to Global Suppressors in the SHV β-Lactamase Family?The evolutionary histories of clinical and environmental SHV β-lactamases are intertwinedHigh adaptability of the omega loop underlies the substrate-spectrum-extension evolution of a class A β-lactamase, PenL.Beta-lactams and beta-lactamase-inhibitors in current- or potential-clinical practice: a comprehensive update.
P2860
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P2860
description
1999 nî lūn-bûn
@nan
1999 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի մայիսին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Structure of the SHV-1 beta-lactamase
@ast
Structure of the SHV-1 beta-lactamase
@en
Structure of the SHV-1 beta-lactamase
@nl
type
label
Structure of the SHV-1 beta-lactamase
@ast
Structure of the SHV-1 beta-lactamase
@en
Structure of the SHV-1 beta-lactamase
@nl
prefLabel
Structure of the SHV-1 beta-lactamase
@ast
Structure of the SHV-1 beta-lactamase
@en
Structure of the SHV-1 beta-lactamase
@nl
P2093
P3181
P356
P1433
P1476
Structure of the SHV-1 beta-lactamase
@en
P2093
P304
P3181
P356
10.1021/BI990136D
P407
P577
1999-05-04T00:00:00Z