Solution structure of alpha-conotoxin ImI by 1H nuclear magnetic resonance
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A new level of conotoxin diversity, a non-native disulfide bond connectivity in alpha-conotoxin AuIB reduces structural definition but increases biological activityProtein Folding Determinants: Structural Features Determining Alternative Disulfide Pairing in α- and χ/λ-Conotoxins † , ‡α-RgIA, a Novel Conotoxin That Blocks the α9α10 nAChR: Structure and Identification of Key Receptor-Binding ResiduesDithiol amino acids can structurally shape and enhance the ligand-binding properties of polypeptidesBlockade of neuronal α7-nAChR by α-conotoxin ImI explained by computational scanning and energy calculationsStructural determinants of selective alpha-conotoxin binding to a nicotinic acetylcholine receptor homolog AChBP.A synthetic combinatorial strategy for developing alpha-conotoxin analogs as potent alpha7 nicotinic acetylcholine receptor antagonists.Conformational flexibility in the binding surface of the potassium channel blocker ShK.Structure-activity relationships of alpha-conotoxins targeting neuronal nicotinic acetylcholine receptors.Less is More: Design of a Highly Stable Disulfide-Deleted Mutant of Analgesic Cyclic α-Conotoxin Vc1.1.Sizing the protein translocation pathway of colicin Ia channels.A novel conotoxin, qc16a, with a unique cysteine framework and foldingIdentifying key amino acid residues that affect α-conotoxin AuIB inhibition of α3β4 nicotinic acetylcholine receptors.Rational design of alpha-conotoxin analogues targeting alpha7 nicotinic acetylcholine receptors: improved antagonistic activity by incorporation of proline derivatives.Acetylcholine promotes binding of α-conotoxin MII at α3 β2 nicotinic acetylcholine receptors.Molecular Engineering of Conus Peptides as Therapeutic Leads.The three-dimensional structure of the analgesic alpha-conotoxin, RgIA.Alpha-selenoconotoxins, a new class of potent alpha7 neuronal nicotinic receptor antagonists.α-Conotoxin ImI-modified polymeric micelles as potential nanocarriers for targeted docetaxel delivery to α7-nAChR overexpressed non-small cell lung cancer.Epimerization-free access to C-terminal cysteine peptide acids, carboxamides, secondary amides, and esters via complimentary strategies.
P2860
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P2860
Solution structure of alpha-conotoxin ImI by 1H nuclear magnetic resonance
description
1999 nî lūn-bûn
@nan
1999 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Solution structure of alpha-conotoxin ImI by 1H nuclear magnetic resonance
@ast
Solution structure of alpha-conotoxin ImI by 1H nuclear magnetic resonance
@en
Solution structure of alpha-conotoxin ImI by 1H nuclear magnetic resonance
@nl
type
label
Solution structure of alpha-conotoxin ImI by 1H nuclear magnetic resonance
@ast
Solution structure of alpha-conotoxin ImI by 1H nuclear magnetic resonance
@en
Solution structure of alpha-conotoxin ImI by 1H nuclear magnetic resonance
@nl
prefLabel
Solution structure of alpha-conotoxin ImI by 1H nuclear magnetic resonance
@ast
Solution structure of alpha-conotoxin ImI by 1H nuclear magnetic resonance
@en
Solution structure of alpha-conotoxin ImI by 1H nuclear magnetic resonance
@nl
P50
P356
P1476
Solution structure of alpha-conotoxin ImI by 1H nuclear magnetic resonance
@en
P2093
Gehrmann J
P304
P356
10.1021/JM990114P
P407
P577
1999-07-01T00:00:00Z