Insights into the mechanism of Escherichia coli methionine aminopeptidase from the structural analysis of reaction products and phosphorus-based transition-state analogues
about
Nonnatural amino acid incorporation into the methionine 214 position of the metzincin Pseudomonas aeruginosa alkaline protease.Interactions of Streptomyces griseus aminopeptidase with amino acid reaction products and their implications toward a catalytic mechanismInhibition of Monometalated Methionine Aminopeptidase: Inhibitor Discovery and Crystallographic Analysis †Structural analysis of inhibition of E. coli methionine aminopeptidase: implication of loop adaptability in selective inhibition of bacterial enzymesStructure of a microsporidian methionine aminopeptidase type 2 complexed with fumagillin and TNP-470Inhibition of Mycobacterium tuberculosis Methionine Aminopeptidases by Bengamide DerivativesStructure of d(CCGGGACCGG)4as a four-way junction at 1.6 Å resolution: new insights into solvent interactionsKinetic and structural evidences on human prolidase pathological mutants suggest strategies for enzyme functional rescueSuperpose3D: a local structural comparison program that allows for user-defined structure representations.Screening a fragment cocktail library using ultrafiltration.Mutations at the S1 sites of methionine aminopeptidases from Escherichia coli and Homo sapiens reveal the residues critical for substrate specificity.Structural basis of catalysis by monometalated methionine aminopeptidaseBridging of a substrate between cyclodextrin and an enzyme's active site pocket triggers a unique mode of inhibitionStructurally distinct active sites in the copper(II)-substituted aminopeptidases from Aeromonas proteolytica and Escherichia coliMutation of H63 and its catalytic affect on the methionine aminopeptidase from Escherichia coli.Analyzing the binding of Co(II)-specific inhibitors to the methionyl aminopeptidases from Escherichia coli and Pyrococcus furiosusKinetic and spectroscopic analysis of the catalytic role of H79 in the methionine aminopeptidase from Escherichia coli.Motif-directed redesign of enzyme specificity.FE(II) is the native cofactor for Escherichia coli methionine aminopeptidase.Dynamic enzyme docking to the ribosome coordinates N-terminal processing with polypeptide folding.Functional and developmental impact of cytosolic protein N-terminal methionine excision in Arabidopsis.Aminopeptidase p mediated detoxification of organophosphonate analogues of sarin: mechanistic and stereochemical study at the phosphorus atom of the substrate.Substrate specificity and reaction mechanism of human prolidase.
P2860
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P2860
Insights into the mechanism of Escherichia coli methionine aminopeptidase from the structural analysis of reaction products and phosphorus-based transition-state analogues
description
1999 nî lūn-bûn
@nan
1999 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Insights into the mechanism of ...... sed transition-state analogues
@ast
Insights into the mechanism of ...... sed transition-state analogues
@en
Insights into the mechanism of ...... sed transition-state analogues
@nl
type
label
Insights into the mechanism of ...... sed transition-state analogues
@ast
Insights into the mechanism of ...... sed transition-state analogues
@en
Insights into the mechanism of ...... sed transition-state analogues
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prefLabel
Insights into the mechanism of ...... sed transition-state analogues
@ast
Insights into the mechanism of ...... sed transition-state analogues
@en
Insights into the mechanism of ...... sed transition-state analogues
@nl
P2093
P356
P1433
P1476
Insights into the mechanism of ...... sed transition-state analogues
@en
P2093
B W Matthews
P B Sampson
W T Lowther
P304
14810-14819
P356
10.1021/BI991711G
P407
P577
1999-11-01T00:00:00Z