Crystal structure of the IMP-1 metallo beta-lactamase from Pseudomonas aeruginosa and its complex with a mercaptocarboxylate inhibitor: binding determinants of a potent, broad-spectrum inhibitor
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Oligomeric structure of proclavaminic acid amidino hydrolase: evolution of a hydrolytic enzyme in clavulanic acid biosynthesisThree decades of beta-lactamase inhibitorsMechanism of the quorum-quenching lactonase (AiiA) from Bacillus thuringiensis. 1. Product-bound structuresCarbapenemases: the versatile beta-lactamasesProbing substrate binding to metallo-beta-lactamase L1 from Stenotrophomonas maltophilia by using site-directed mutagenesisIdentification of a series of tricyclic natural products as potent broad-spectrum inhibitors of metallo-beta-lactamases.Competitive Inhibitors of the CphA Metallo- -Lactamase from Aeromonas hydrophilaStructural and functional characterization ofSalmonella entericaserovar Typhimurium YcbL: An unusual Type II glyoxalaseA structural view of the antibiotic degradation enzyme NDM-1 from a superbugMutagenesis of Zinc Ligand Residue Cys221 Reveals Plasticity in the IMP-1 Metallo- -Lactamase Active SiteStructure of Apo- and Monometalated Forms of NDM-1—A Highly Potent Carbapenem-Hydrolyzing Metallo-β-LactamaseCrystal Structures of Pseudomonas aeruginosa GIM-1: Active-Site Plasticity in Metallo- -LactamasesCrystal Structure of the Mobile Metallo- -Lactamase AIM-1 from Pseudomonas aeruginosa: Insights into Antibiotic Binding and the Role of Gln157Solution structures of the Bacillus cereus metallo-β-lactamase BcII and its complex with the broad spectrum inhibitor R -thiomandelic acidHis224 Alters the R2 Drug Binding Site and Phe218 Influences the Catalytic Efficiency of the Metallo- -Lactamase VIM-7Overcoming differences: The catalytic mechanism of metallo-β-lactamasesStructural basis for carbapenem-hydrolyzing mechanisms of carbapenemases conferring antibiotic resistanceIdentification of residues critical for metallo-beta-lactamase function by codon randomization and selectionInsights from modeling the 3D structure of New Delhi metallo-β-lactamse and its binding interactions with antibiotic drugsEvolving carbapenemases: can medicinal chemists advance one step ahead of the coming storm?A case study comparing quantitative stability-flexibility relationships across five metallo-β-lactamases highlighting differences within NDM-1.Metallo-beta-lactamase producers in environmental microbiota: new molecular class B enzyme in Janthinobacterium lividum.Mimicking natural evolution in metallo-beta-lactamases through second-shell ligand mutations.Metallo-beta-lactamases: the quiet before the storm?Mutational analysis of VIM-2 reveals an essential determinant for metallo-beta-lactamase stability and folding.Molecular mechanisms of substrate recognition and specificity of New Delhi metallo-β-lactamaseChromosome-encoded beta-lactamases TUS-1 and MUS-1 from Myroides odoratus and Myroides odoratimimus (formerly Flavobacterium odoratum), new members of the lineage of molecular subclass B1 metalloenzymes.Computational analysis of pathogen-borne metallo β-lactamases reveals discriminating structural features between B1 types.Evolution of Metallo-β-lactamases: Trends Revealed by Natural Diversity and in vitro EvolutionStructural Basis of Metallo-β-Lactamase Inhibition by Captopril StereoisomersBiochemical, mechanistic, and spectroscopic characterization of metallo-β-lactamase VIM-2.Anisotropic, Polarizable Molecular Mechanics Studies of Inter- and Intramolecular Interactions and Ligand-Macromolecule Complexes. A Bottom-Up Strategy.IMP-12, a new plasmid-encoded metallo-beta-lactamase from a Pseudomonas putida clinical isolate.Azolylthioacetamide: A Highly Promising Scaffold for the Development of Metallo-β-lactamase Inhibitors.Analysis of the functional contributions of Asn233 in metallo-β-lactamase IMP-1Amino Acid Thioester Derivatives: A Highly Promising Scaffold for the Development of Metallo-β-lactamase L1 Inhibitors.Crystal Structure of DIM-1, an Acquired Subclass B1 Metallo-β-Lactamase from Pseudomonas stutzeri.Differential binding of Co(II) and Zn(II) to metallo-beta-lactamase Bla2 from Bacillus anthracis.Crystallization and preliminary X-ray analysis of the subclass B3 metallo-β-lactamase SMB-1 that confers carbapenem resistance.Elucidating the Role of Residue 67 in IMP-Type Metallo-β-Lactamase Evolution.
P2860
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P2860
Crystal structure of the IMP-1 metallo beta-lactamase from Pseudomonas aeruginosa and its complex with a mercaptocarboxylate inhibitor: binding determinants of a potent, broad-spectrum inhibitor
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2000 nî lūn-bûn
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2000 թուականի Ապրիլին հրատարակուած գիտական յօդուած
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2000 թվականի ապրիլին հրատարակված գիտական հոդված
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2000年の論文
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2000年論文
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2000年論文
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2000年論文
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name
Crystal structure of the IMP-1 ...... tent, broad-spectrum inhibitor
@ast
Crystal structure of the IMP-1 ...... tent, broad-spectrum inhibitor
@en
Crystal structure of the IMP-1 ...... tent, broad-spectrum inhibitor
@nl
type
label
Crystal structure of the IMP-1 ...... tent, broad-spectrum inhibitor
@ast
Crystal structure of the IMP-1 ...... tent, broad-spectrum inhibitor
@en
Crystal structure of the IMP-1 ...... tent, broad-spectrum inhibitor
@nl
prefLabel
Crystal structure of the IMP-1 ...... tent, broad-spectrum inhibitor
@ast
Crystal structure of the IMP-1 ...... tent, broad-spectrum inhibitor
@en
Crystal structure of the IMP-1 ...... tent, broad-spectrum inhibitor
@nl
P2093
P1433
P1476
Crystal structure of the IMP-1 ...... tent, broad-spectrum inhibitor
@en
P2093
B P Clarke
C A Cheever
C A Janson
J H Bateson
N O Concha
P304
P407
P577
2000-04-18T00:00:00Z