Crystallographic evidence for Tyr 157 functioning as the active site base in human UDP-galactose 4-epimerase
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The human L-threonine 3-dehydrogenase gene is an expressed pseudogene.Structure and mechanism of ArnA: conformational change implies ordered dehydrogenase mechanism in key enzyme for polymyxin resistanceMedium- and short-chain dehydrogenase/reductase gene and protein families : the SDR superfamily: functional and structural diversity within a family of metabolic and regulatory enzymesCrystal structure of Escherichia coli ArnA (PmrI) decarboxylase domain. A key enzyme for lipid A modification with 4-amino-4-deoxy-L-arabinose and polymyxin resistanceGalactose toxicity in animalsMolecular cloning and tissue distribution of mammalian L-threonine 3-dehydrogenasesHuman UDP-galactose 4-epimerase. Accommodation of UDP-N-acetylglucosamine within the active siteMolecular basis for severe epimerase deficiency galactosemia. X-ray structure of the human V94m-substituted UDP-galactose 4-epimeraseThe structure of the negative transcriptional regulator NmrA reveals a structural superfamily which includes the short-chain dehydrogenase/reductasesStructural analysis of the Y299C mutant of Escherichia coli UDP-galactose 4-epimerase. Teaching an old dog new tricksHigh resolution x-ray structure of tyvelose epimerase from Salmonella typhiThe negative transcriptional regulator NmrA discriminates between oxidized and reduced dinucleotidesMolecular structure of galactokinaseCrystal structure of a tetrameric GDP-D-mannose 4,6-dehydratase from a bacterial GDP-D-rhamnose biosynthetic pathwayPredicting Protein Function from Structure—The Roles of Short-chain Dehydrogenase/Reductase Enzymes in Bordetella O-antigen BiosynthesisCrystal structure of UDP-galactose 4-epimerase-like L-threonine dehydrogenase belonging to the intermediate short-chain dehydrogenase-reductase superfamilyAltered architecture of substrate binding region defines the unique specificity of UDP-GalNAc 4-epimerasesCrystal Structure of Binary and Ternary Complexes of Archaeal UDP-galactose 4-Epimerase-like l-Threonine Dehydrogenase fromThermoplasma volcaniumAtomic-Resolution Structures of Horse Liver Alcohol Dehydrogenase with NAD + and Fluoroalcohols Define Strained Michaelis ComplexesElucidation of substrate specificity in Aspergillus nidulans UDP-galactose-4-epimeraseCrystallographic analysis and structure-guided engineering of NADPH-dependent Ralstonia sp. alcohol dehydrogenase toward NADH cosubstrate specificityDeterminants of function and substrate specificity in human UDP-galactose 4'-epimeraseIdentification of two GDP-6-deoxy-D-lyxo-4-hexulose reductases synthesizing GDP-D-rhamnose in Aneurinibacillus thermoaerophilus L420-91TThe molecular basis of UDP-galactose-4-epimerase (GALE) deficiency galactosemia in Korean patientsA rice plastidial nucleotide sugar epimerase is involved in galactolipid biosynthesis and improves photosynthetic efficiencyIRECS: a new algorithm for the selection of most probable ensembles of side-chain conformations in protein models.Molecular cloning, sequence analysis and homology modeling of galE encoding UDP-galactose 4-epimerase of Aeromonas hydrophilaStructural studies of FlaA1 from Helicobacter pylori reveal the mechanism for inverting 4,6-dehydratase activity.Preliminary X-ray crystallographic studies of UDP-glucose-4-epimerase from Aspergillus nidulansIn vivo and in vitro function of human UDP-galactose 4'-epimerase variants.UDP-galactose 4'-epimerase from the liver fluke, Fasciola hepatica: biochemical characterization of the enzyme and identification of inhibitors.Altered cofactor binding affects stability and activity of human UDP-galactose 4'-epimerase: implications for type III galactosemiaInsights into role of the hydrogen bond networks in substrate recognition by UDP-GalNAc 4-epimerases.Origins of stereoselectivity in evolved ketoreductases.Comparison of dynamics of wildtype and V94M human UDP-galactose 4-epimerase-A computational perspective on severe epimerase-deficiency galactosemia.Liver glucose metabolism in humans.The renaissance of bacillosamine and its derivatives: pathway characterization and implications in pathogenicity.A structurally conserved water molecule in Rossmann dinucleotide-binding domains.Functional characterization of Gne (UDP-N-acetylglucosamine-4-epimerase), Wzz (chain length determinant), and Wzy (O-antigen polymerase) of Yersinia enterocolitica serotype O:8Structure-function studies of two novel UDP-GlcNAc C6 dehydratases/C4 reductases. Variation from the SYK dogma.
P2860
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P2860
Crystallographic evidence for Tyr 157 functioning as the active site base in human UDP-galactose 4-epimerase
description
2000 nî lūn-bûn
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2000 թուականի Մայիսին հրատարակուած գիտական յօդուած
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2000 թվականի մայիսին հրատարակված գիտական հոդված
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2000年の論文
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2000年論文
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2000年論文
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2000年論文
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2000年論文
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2000年論文
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2000年论文
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name
Crystallographic evidence for ...... uman UDP-galactose 4-epimerase
@ast
Crystallographic evidence for ...... uman UDP-galactose 4-epimerase
@en
Crystallographic evidence for ...... uman UDP-galactose 4-epimerase
@nl
type
label
Crystallographic evidence for ...... uman UDP-galactose 4-epimerase
@ast
Crystallographic evidence for ...... uman UDP-galactose 4-epimerase
@en
Crystallographic evidence for ...... uman UDP-galactose 4-epimerase
@nl
prefLabel
Crystallographic evidence for ...... uman UDP-galactose 4-epimerase
@ast
Crystallographic evidence for ...... uman UDP-galactose 4-epimerase
@en
Crystallographic evidence for ...... uman UDP-galactose 4-epimerase
@nl
P2093
P356
P1433
P1476
Crystallographic evidence for ...... uman UDP-galactose 4-epimerase
@en
P2093
H M Holden
J B Thoden
J L Fridovich-Keil
T M Wohlers
P304
P356
10.1021/BI000215L
P407
P577
2000-05-16T00:00:00Z