"Open" structures of MurD: domain movements and structural similarities with folylpolyglutamate synthetase
about
Structure of MurF from Streptococcus pneumoniae co-crystallized with a small molecule inhibitor exhibits interdomain closureCrystal structure of UDP-N-acetylmuramoyl-L-alanyl-D-glutamate: meso-diaminopimelate ligase from Escherichia coliCrystal Structures of Active Fully Assembled Substrate- and Product-Bound Complexes of UDP-N-Acetylmuramic Acid:L-Alanine Ligase (MurC) from Haemophilus influenzaeSpecificity Determinants for Lysine Incorporation in Staphylococcus aureus Peptidoglycan as Revealed by the Structure of a MurE Enzyme Ternary ComplexMreB and MurG as scaffolds for the cytoplasmic steps of peptidoglycan biosynthesisGlutathione synthetase homologs encode alpha-L-glutamate ligases for methanogenic coenzyme F420 and tetrahydrosarcinapterin biosynthesesThe binding mode of second-generation sulfonamide inhibitors of MurD: clues for rational design of potent MurD inhibitorsCrystallographic Study of Peptidoglycan Biosynthesis Enzyme MurD: Domain Movement RevisitedPhage display-derived inhibitor of the essential cell wall biosynthesis enzyme MurF.Pseudomonas aeruginosa MurE amide ligase: enzyme kinetics and peptide inhibitor.Packing interface energetics in different crystal forms of the λ Cro dimer.Virtual screening for potential inhibitors of homology modeled Leptospira interrogans MurD ligaseThe bacterial cell wall as a source of antibacterial targets.Interaction of N-methyl-2-alkenyl-4-quinolones with ATP-dependent MurE ligase of Mycobacterium tuberculosis: antibacterial activity, molecular docking and inhibition kineticsStructural and functional features of enzymes of Mycobacterium tuberculosis peptidoglycan biosynthesis as targets for drug development.Cytoplasmic steps of peptidoglycan biosynthesis.Peptidoglycan biosynthesis machinery: a rich source of drug targets.The biology of Mur ligases as an antibacterial target.Evidence of a functional requirement for a carbamoylated lysine residue in MurD, MurE and MurF synthetases as established by chemical rescue experiments.Characterization of the Bacillus subtilis ywsC gene, involved in gamma-polyglutamic acid production.Furan-based benzene mono- and dicarboxylic acid derivatives as multiple inhibitors of the bacterial Mur ligases (MurC-MurF): experimental and computational characterization.Ligand-driven conformational changes of MurD visualized by paramagnetic NMR.Structure and inhibition of N-acetylneuraminate lyase from methicillin-resistant Staphylococcus aureus.Molecular dynamics simulation and linear interaction energy study of D-Glu-based inhibitors of the MurD ligase.Escherichia coli FolC structure reveals an unexpected dihydrofolate binding site providing an attractive target for anti-microbial therapy.
P2860
Q24644604-F323BBF3-2891-40F4-8885-77605F3C2BC4Q27629001-5FE23479-023E-48D0-97B9-6B77DD383D8AQ27641592-56F0E81D-23AD-4250-A45B-8D627C7C2B72Q27680042-EC3DAC9D-A1DC-417D-9400-16BAEEA10D92Q27685172-3B2B832E-B398-417D-BD30-AE34BD06B6DCQ28156417-969052D6-E355-47CA-B9B4-9A60E8DDC0D3Q28484507-79286062-A0C5-4CEC-9291-CA2673DAE762Q28551115-ACE2C9EB-D401-4950-BB83-91C1F64574BAQ30855747-71202B68-A935-4ED8-9417-D88E33391C79Q33435982-25CB9C41-16E2-4DE1-B593-00DD5DE5758EQ33599950-249529F0-934B-406E-80B6-B67B54832F70Q33897752-E6766B1E-628E-4F29-B42F-482CE6945A03Q34568935-FC293434-CE1C-4BC5-AFB8-83D928111D49Q35096913-A2ABD354-7DC1-4868-AB5A-BFBDA4A6752DQ36319020-68695C54-0D42-49BA-B350-696CCC7E8880Q37081699-93A8E736-BF87-4450-A430-0131633D2640Q37810971-4F0B26AB-4C9E-4900-AAFC-071D4F7A7351Q38240597-8B9E6965-A17E-4E62-B74B-3BBAA414EBF1Q38294460-044D2359-002D-4875-A810-1027A1C274FCQ39694674-187325FC-4152-463B-B584-460E8255241DQ41103702-96E12067-809C-4D56-84F7-83C53AE154C1Q43165180-3388D5D2-9362-4748-B410-DC5A57489048Q43436641-728F8332-72F1-4059-83E3-E107F46E5B57Q43703243-7A989A43-573E-42CF-A1B0-7CAABE6AFA6BQ45261036-C0551832-E166-4E64-A139-F52A46F25048
P2860
"Open" structures of MurD: domain movements and structural similarities with folylpolyglutamate synthetase
description
2000 nî lūn-bûn
@nan
2000 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
"Open" structures of MurD: dom ...... folylpolyglutamate synthetase
@ast
"Open" structures of MurD: dom ...... folylpolyglutamate synthetase
@en
"Open" structures of MurD: dom ...... folylpolyglutamate synthetase
@nl
type
label
"Open" structures of MurD: dom ...... folylpolyglutamate synthetase
@ast
"Open" structures of MurD: dom ...... folylpolyglutamate synthetase
@en
"Open" structures of MurD: dom ...... folylpolyglutamate synthetase
@nl
prefLabel
"Open" structures of MurD: dom ...... folylpolyglutamate synthetase
@ast
"Open" structures of MurD: dom ...... folylpolyglutamate synthetase
@en
"Open" structures of MurD: dom ...... folylpolyglutamate synthetase
@nl
P2093
P3181
P356
P1476
"Open" structures of MurD: dom ...... folylpolyglutamate synthetase
@en
P2093
J A Bertrand
J van Heijenoort
L Chantalat
O Dideberg
P304
P3181
P356
10.1006/JMBI.2000.3994
P407
P577
2000-09-01T00:00:00Z