Functional anticodon architecture of human tRNALys3 includes disruption of intraloop hydrogen bonding by the naturally occurring amino acid modification, t6A
about
Purine bases at position 37 of tRNA stabilize codon-anticodon interaction in the ribosomal A site by stacking and Mg2+-dependent interactions.Post-transcriptional nucleotide modification and alternative folding of RNAExploiting tRNAs to Boost VirulenceDiversity of the biosynthesis pathway for threonylcarbamoyladenosine (t(6)A), a universal modification of tRNAThe structure of the human tRNALys3 anticodon bound to the HIV genome is stabilized by modified nucleosides and adjacent mismatch base pairsCrystal structure of Sulfolobus tokodaii Sua5 complexed with L-threonine and AMPPNPConformation Effects of Base Modification on the Anticodon Stem–Loop of Bacillus subtilis tRNATyrHuman tRNALys3UUU Is Pre-Structured by Natural Modifications for Cognate and Wobble Codon Binding through Keto–Enol TautomerismStructure ofSaccharomyces cerevisiaemitochondrial Qri7 in complex with AMPThe universal YrdC/Sua5 family is required for the formation of threonylcarbamoyladenosine in tRNA.The highly conserved KEOPS/EKC complex is essential for a universal tRNA modification, t6A.Functional assignment of KEOPS/EKC complex subunits in the biosynthesis of the universal t6A tRNA modification.Gcn4 misregulation reveals a direct role for the evolutionary conserved EKC/KEOPS in the t6A modification of tRNAsA cyclic form of N6-threonylcarbamoyladenosine as a widely distributed tRNA hypermodification.The Sua5 protein is essential for normal translational regulation in yeast.Discovery of the β-barrel-type RNA methyltransferase responsible for N6-methylation of N6-threonylcarbamoyladenosine in tRNAsBiosynthesis of threonylcarbamoyl adenosine (t6A), a universal tRNA nucleosideThe crystal structure and small-angle X-ray analysis of CsdL/TcdA reveal a new tRNA binding motif in the MoeB/E1 superfamilyA hydantoin isoform of cyclic N6-threonylcarbamoyladenosine (ct6A) is present in tRNAsFunctional recognition of the modified human tRNALys3(UUU) anticodon domain by HIV's nucleocapsid protein and a peptide mimic.Decoding the genome: a modified view.In vitro biosynthesis of a universal t6A tRNA modification in Archaea and EukaryaA role for the universal Kae1/Qri7/YgjD (COG0533) family in tRNA modification.Molecular dynamics simulations of human tRNA Lys,3 UUU: the role of modified bases in mRNA recognition.YrdC exhibits properties expected of a subunit for a tRNA threonylcarbamoyl transferase.tRNA's modifications bring order to gene expressionBringing order to translation: the contributions of transfer RNA anticodon-domain modifications.Synthesis of oligoribonucleotides containing N6-alkyladenosine and 2-methylthio-N6-alkyladenosine.Amino acid signature enables proteins to recognize modified tRNA.Structure and function of noncanonical nucleobases.Nuclear-encoded factors involved in post-transcriptional processing and modification of mitochondrial tRNAs in human disease.Capture and Release of tRNA by the T-Loop Receptor in the Function of the T-Box Riboswitch.Chemical and Conformational Diversity of Modified Nucleosides Affects tRNA Structure and FunctionThe synthesis of oligoribonucleotides containing N6-alkyladenosines and 2-methylthio-N6-alkyladenosines via post-synthetic modification of precursor oligomersThe thermodynamic stability of RNA duplexes and hairpins containing N6-alkyladenosines and 2-methylthio-N6-alkyladenosines.Structural effects of modified ribonucleotides and magnesium in transfer RNAs.The influence of hypermodified nucleosides lysidine and t(6)A to recognize the AUA codon instead of AUG: a molecular dynamics simulation study.The naturally occurring N6-threonyl adenine in anticodon loop of Schizosaccharomyces pombe tRNAi causes formation of a unique U-turn motif.Kluyveromyces lactis gamma-toxin, a ribonuclease that recognizes the anticodon stem loop of tRNA.Structural features of tRNALys favored by anticodon nuclease as inferred from reactivities of anticodon stem and loop substrate analogs.
P2860
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P2860
Functional anticodon architecture of human tRNALys3 includes disruption of intraloop hydrogen bonding by the naturally occurring amino acid modification, t6A
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2000 nî lūn-bûn
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2000 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
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2000 թվականի նոյեմբերին հրատարակված գիտական հոդված
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2000年の論文
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2000年論文
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2000年論文
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2000年論文
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2000年論文
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Functional anticodon architect ...... g amino acid modification, t6A
@ast
Functional anticodon architect ...... g amino acid modification, t6A
@en
Functional anticodon architect ...... g amino acid modification, t6A
@nl
type
label
Functional anticodon architect ...... g amino acid modification, t6A
@ast
Functional anticodon architect ...... g amino acid modification, t6A
@en
Functional anticodon architect ...... g amino acid modification, t6A
@nl
prefLabel
Functional anticodon architect ...... g amino acid modification, t6A
@ast
Functional anticodon architect ...... g amino acid modification, t6A
@en
Functional anticodon architect ...... g amino acid modification, t6A
@nl
P2093
P356
P1433
P1476
Functional anticodon architect ...... g amino acid modification, t6A
@en
P2093
A Malkiewicz
E Sochacka
J W Stuart
M Marszalek
R Guenther
P304
P356
10.1021/BI0013039
P407
P577
2000-11-07T00:00:00Z