Crystal structure of a complement control protein that regulates both pathways of complement activation and binds heparan sulfate proteoglycans
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Structure of the N-terminal region of complement factor H and conformational implications of disease-linked sequence variationsThe crystal structure of the zymogen catalytic domain of complement protease C1r reveals that a disruptive mechanical stress is required to trigger activation of the C1 complex.Structure of decay-accelerating factor bound to echovirus 7: a virus-receptor complex.Solution structure of a functionally active fragment of decay-accelerating factorComplement regulation at the molecular level: The structure of decay-accelerating factorThe structure of C2b, a fragment of complement component C2 produced during C3 convertase formationStructural analysis of the complement control protein (CCP) modules of GABA(B) receptor 1a: only one of the two CCP modules is compactly foldedIdentification of complement regulatory domains in vaccinia virus complement control protein.MHV68 complement regulatory protein facilitates MHV68 replication in primary macrophages in a complement independent manner.Complement evasion by human pathogens.Epitope-mapping studies define two major neutralization sites on the vaccinia virus extracellular enveloped virus glycoprotein B5R.The distal short consensus repeats 1 and 2 of the membrane cofactor protein CD46 and their distance from the cell membrane determine productive entry of species B adenovirus serotype 35Smallpox inhibitor of complement enzymes (SPICE): dissecting functional sites and abrogating activityMicrobial subversion of the immune response.Variola virus immune evasion design: expression of a highly efficient inhibitor of human complement.Electrostatic modeling predicts the activities of orthopoxvirus complement control proteinsEctromelia virus inhibitor of complement enzymes protects intracellular mature virus and infected cells from mouse complement.Conformational states of a bacterial α2-macroglobulin resemble those of human complement C3.The agnoprotein of polyomavirus JC is released by infected cells: evidence for its cellular uptake by uninfected neighboring cells.Immunophysical properties and prediction of activities for vaccinia virus complement control protein and smallpox inhibitor of complement enzymes using molecular dynamics and electrostatics.Structure of vaccinia complement protein in complex with heparin and potential implications for complement regulation.Heparin-protein interactions.Poxvirus immunomodulatory strategies: current perspectivesRestoration of complement-enhanced neutralization of vaccinia virus virions by novel monoclonal antibodies raised against the vaccinia virus complement control protein.Enhancing complement control on endothelial barrier reduces renal post-ischemia dysfunctionDisabling complement regulatory activities of vaccinia virus complement control protein reduces vaccinia virus pathogenicity.An ectromelia virus protein that interacts with chemokines through their glycosaminoglycan binding domain.Identification of hot spots in the variola virus complement inhibitor (SPICE) for human complement regulation.Membrane-proximal TRAIL species are incapable of inducing short circuit apoptosis signaling: Implications for drug development and basic cytokine biologyInhibition of complement and CD14 attenuates the Escherichia coli-induced inflammatory response in porcine whole blood.Kinetic analysis of the interactions between vaccinia virus complement control protein and human complement proteins C3b and C4b.Smallpox inhibitor of complement enzymes (SPICE): regulation of complement activation on cells and mechanism of its cellular attachment.Poxvirus proteomics and virus-host protein interactions.Viral-derived complement inhibitors: current status and potential role in immunomodulation.Influence of glycosylation and oligomerization of vaccinia virus complement control protein on level and pattern of functional activity and immunogenicity.Cell surface targeting of pregnancy-associated plasma protein A proteolytic activity. Reversible adhesion is mediated by two neighboring short consensus repeats.Dissecting the regions of virion-associated Kaposi's sarcoma-associated herpesvirus complement control protein required for complement regulation and cell binding.Backbone dynamics of complement control protein (CCP) modules reveals mobility in binding surfaces.The Kaposi's sarcoma-associated herpesvirus complement control protein mimics human molecular mechanisms for inhibition of the complement system.The structure of complement C3b provides insights into complement activation and regulation.
P2860
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P2860
Crystal structure of a complement control protein that regulates both pathways of complement activation and binds heparan sulfate proteoglycans
description
2001 nî lūn-bûn
@nan
2001 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Crystal structure of a complem ...... heparan sulfate proteoglycans
@ast
Crystal structure of a complem ...... heparan sulfate proteoglycans
@en
Crystal structure of a complem ...... heparan sulfate proteoglycans
@nl
type
label
Crystal structure of a complem ...... heparan sulfate proteoglycans
@ast
Crystal structure of a complem ...... heparan sulfate proteoglycans
@en
Crystal structure of a complem ...... heparan sulfate proteoglycans
@nl
prefLabel
Crystal structure of a complem ...... heparan sulfate proteoglycans
@ast
Crystal structure of a complem ...... heparan sulfate proteoglycans
@en
Crystal structure of a complem ...... heparan sulfate proteoglycans
@nl
P2093
P1433
P1476
Crystal structure of a complem ...... heparan sulfate proteoglycans
@en
P2093
G J Kotwal
K H Murthy
P N Barlow
V K Ganesh
P304
P356
10.1016/S0092-8674(01)00214-8
P407
P577
2001-01-26T00:00:00Z