Two new classes of conopeptides inhibit the alpha1-adrenoceptor and noradrenaline transporter - Test2 - elhamkhani - TriplyDB

Two new classes of conopeptides inhibit the alpha1-adrenoceptor and noradrenaline transporter

Two new classes of conopeptides inhibit the alpha1-adrenoceptor and noradrenaline transporter

http://www.wikidata.org/entity/Q27634633

about

A new level of conotoxin diversity, a non-native disulfide bond connectivity in alpha-conotoxin AuIB reduces structural definition but increases biological activity Protein Folding Determinants: Structural Features Determining Alternative Disulfide Pairing in α- and χ/λ-Conotoxins † , ‡Solution structure of an M-1 conotoxin with a novel disulfide linkage Structure of α-conotoxin BuIA: influences of disulfide connectivity on structural dynamics Conopeptide -TIA Defines a New Allosteric Site on the Extracellular Surface of the 1B-Adrenoceptor BmK-YA, an enkephalin-like peptide in scorpion venom Diversity of conotoxin gene superfamilies in the venomous snail, Conus victoriae Role of voltage-gated calcium channels in ascending pain pathways Tyrosine-rich conopeptides affect voltage-gated K+ channels.Conus peptides: biodiversity-based discovery and exogenomics.High-threshold mechanosensitive ion channels blocked by a novel conopeptide mediate pressure-evoked pain Isolation and pharmacological characterization of AdTx1, a natural peptide displaying specific insurmountable antagonism of the alpha1A-adrenoceptor.Bioactive marine drugs and marine biomaterials for brain diseases The Venom Repertoire of Conus gloriamaris (Chemnitz, 1777), the Glory of the Sea.Diversity of conotoxin types from Conus californicus reflects a diversity of prey types and a novel evolutionary history.Identification of a novel snake peptide toxin displaying high affinity and antagonist behaviour for the α2-adrenoceptors.Deep venomics reveals the mechanism for expanded peptide diversity in cone snail venom Oxidative folding and preparation of α-conotoxins for use in high-throughput structure-activity relationship studies.Conotoxin gene superfamilies.Spider-venom peptides as therapeutics.Cone snail venomics: from novel biology to novel therapeutics.Analgesic conotoxins: block and G protein-coupled receptor modulation of N-type (Ca(V) 2.2) calcium channels.Recent progress in alpha1-adrenergic receptor research.The solute carrier 6 family of transporters Ancestral protein resurrection and engineering opportunities of the mamba aminergic toxins A novel conotoxin, qc16a, with a unique cysteine framework and folding High-throughput identification of novel conotoxins from the Chinese tubular cone snail (Conus betulinus) by multi-transcriptome sequencing De novo sequencing and disulfide mapping of a bromotryptophan-containing conotoxin by Fourier transform ion cyclotron resonance mass spectrometry.Synthesis and solid-phase application of suitably protected gamma-hydroxyvaline building blocks.Targeting voltage-gated calcium channels for neuropathic pain management.Selective targeting of G-protein-coupled receptor subtypes with venom peptides.Therapeutic potential of conopeptides.Venom-based biotoxins as potential analgesics.Therapeutic conotoxins: a US patent literature survey.The role of defensive ecological interactions in the evolution of conotoxins.A Transcriptomic Survey of Ion Channel-Based Conotoxins in the Chinese Tubular Cone Snail (Conus betulinus).Pharmacokinetics and pharmacodynamics of intrathecally administered Xen2174, a synthetic conopeptide with norepinephrine reuptake inhibitor and analgesic properties.Influence of disulfide connectivity on structure and bioactivity of α-conotoxin TxIA.Novel alpha-conotoxins from Conus spurius and the alpha-conotoxin EI share high-affinity potentiation and low-affinity inhibition of nicotinic acetylcholine receptors.α-Conotoxin Vc1.1 inhibits human dorsal root ganglion neuroexcitability and mouse colonic nociception via GABAB receptors.

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P2860

Two new classes of conopeptides inhibit the alpha1-adrenoceptor and noradrenaline transporter

http://www.wikidata.org/entity/Q27634633

description

2001 nî lūn-bûn

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2001 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

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2001 թվականի սեպտեմբերին հրատարակված գիտական հոդված

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2001年の論文

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2001年論文

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2001年論文

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2001年論文

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2001年論文

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2001年論文

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2001年论文

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name

Two new classes of conopeptide ...... and noradrenaline transporter

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Two new classes of conopeptide ...... and noradrenaline transporter

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Two new classes of conopeptide ...... and noradrenaline transporter

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type

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Two new classes of conopeptide ...... and noradrenaline transporter

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Two new classes of conopeptide ...... and noradrenaline transporter

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Two new classes of conopeptide ...... and noradrenaline transporter

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prefLabel

Two new classes of conopeptide ...... and noradrenaline transporter

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Two new classes of conopeptide ...... and noradrenaline transporter

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Two new classes of conopeptide ...... and noradrenaline transporter

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Nature Neuroscience

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Two new classes of conopeptide ...... and noradrenaline transporter

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Adams DA

http://www.w3.org/2001/XMLSchema#string

Adams DJ

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Atkins A

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Gehrmann J

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Lewis RJ

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Loughnan ML

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Palant E

http://www.w3.org/2001/XMLSchema#string

Sharpe IA

http://www.w3.org/2001/XMLSchema#string

Thomas L

http://www.w3.org/2001/XMLSchema#string

P2860

The 1.1 A crystal structure of the neuronal acetylcholine receptor antagonist, alpha-conotoxin PnIA from Conus pennaceus

Crystal structure at 1.1 A resolution of alpha-conotoxin PnIB: comparison with alpha-conotoxins PnIA and GI

The 1.1 A resolution crystal structure of [Tyr15]EpI, a novel alpha-conotoxin from Conus episcopatus, solved by direct methods

Binding of antidepressants to human brain receptors: focus on newer generation compounds

Contulakin-G, an O-glycosylated invertebrate neurotensin

Isolation and characterization of a novel conus peptide with apparent antinociceptive activity.

lambda-conotoxins, a new family of conotoxins with unique disulfide pattern and protein folding. Isolation and characterization from the venom of Conus marmoreus.

An O-glycosylated neuroexcitatory conus peptide.

Transmitters involved in antinociception in the spinal cord.

Conotoxins, in retrospect.

P2888

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902-907

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scholarly article

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2306324

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10.1038/NN0901-902

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9

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4

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2001-09-01T00:00:00Z

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11818423

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1020914274

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11528421

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