Crystal structure of the macrocycle-forming thioesterase domain of the erythromycin polyketide synthase: Versatility from a unique substrate channel
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The structure of ActVA-Orf6, a novel type of monooxygenase involved in actinorhodin biosynthesis.Structure and Functional Analysis of RifR, the Type II Thioesterase from the Rifamycin Biosynthetic PathwayCrystal Structures of Dehydratase Domains from the Curacin Polyketide Biosynthetic PathwayStructure and function of an iterative polyketide synthase thioesterase domain catalyzing Claisen cyclization in aflatoxin biosynthesisBiochemical and Structural Characterization of the Tautomycetin Thioesterase: Analysis of a Stereoselective Polyketide HydrolaseTerminal Alkene Formation by the Thioesterase of Curacin A Biosynthesis: STRUCTURE OF A DECARBOXYLATING THIOESTERASEStructure and Function of the RedJ Protein, a Thioesterase from the Prodiginine Biosynthetic Pathway in Streptomyces coelicolorStructural Basis of Functional Group Activation by Sulfotransferases in Complex Metabolic PathwaysStructural Basis for Phosphopantetheinyl Carrier Domain Interactions in the Terminal Module of Nonribosomal Peptide SynthetasesThe Missing Linker: A Dimerization Motif Located within Polyketide Synthase ModulesStructural Studies of an A2-Type Modular Polyketide Synthase Ketoreductase Reveal Features Controlling α-Substituent StereochemistryDivergence of multimodular polyketide synthases revealed by a didomain structureArchitecture of the polyketide synthase module: surprises from electron cryo-microscopyRecent advances in the elucidation of enzymatic function in natural product biosynthesisBiosynthesis of Dictyostelium discoideum differentiation-inducing factor by a hybrid type I fatty acid-type III polyketide synthase.Structural enzymology of polyketide synthases.Acyltransferase mediated polyketide release from a fungal megasynthaseGilR, an unusual lactone-forming enzyme involved in gilvocarcin biosynthesis.Cyclization of aromatic polyketides from bacteria and fungiInsights from the sea: structural biology of marine polyketide synthasesArchitectures of whole-module and bimodular proteins from the 6-deoxyerythronolide B synthaseType I polyketide synthase requiring a discrete acyltransferase for polyketide biosynthesisProbing intra- versus interchain kinetic preferences of L-Thr acylation on dimeric VibF with mass spectrometry.The enzymology of combinatorial biosynthesis.A method for prediction of the locations of linker regions within large multifunctional proteins, and application to a type I polyketide synthase.Combinatorial biosynthesis of reduced polyketides.The biosynthesis, molecular genetics and enzymology of the polyketide-derived metabolites.The type I fatty acid and polyketide synthases: a tale of two megasynthasesPolyketide Ring Expansion Mediated by a Thioesterase, Chain Elongation and Cyclization Domain, in Azinomycin Biosynthesis: Characterization of AziB and AziG.Ketide Synthase (KS) Domain Prediction and Analysis of Iterative Type II PKS Gene in Marine Sponge-Associated Actinobacteria Producing Biosurfactants and Antimicrobial AgentsMechanism of thioesterase-catalyzed chain release in the biosynthesis of the polyether antibiotic nanchangmycin.Selective removal of aberrant extender units by a type II thioesterase for efficient FR-008/candicidin biosynthesis in Streptomyces sp. strain FR-008.Structural analysis of protein-protein interactions in type I polyketide synthasesStructural insights into nonribosomal peptide enzymatic assembly linesHuman fatty acid synthase: structure and substrate selectivity of the thioesterase domain.Epimerization and substrate gating by a TE domain in β-lactam antibiotic biosynthesis.PKS and NRPS release mechanisms.Frontiers and opportunities in chemoenzymatic synthesis.The structures of type I polyketide synthases.The structural role of the carrier protein--active controller or passive carrier.
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P2860
Crystal structure of the macrocycle-forming thioesterase domain of the erythromycin polyketide synthase: Versatility from a unique substrate channel
description
2001 nî lūn-bûn
@nan
2001 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Crystal structure of the macro ...... rom a unique substrate channel
@ast
Crystal structure of the macro ...... rom a unique substrate channel
@en
Crystal structure of the macro ...... rom a unique substrate channel
@nl
type
label
Crystal structure of the macro ...... rom a unique substrate channel
@ast
Crystal structure of the macro ...... rom a unique substrate channel
@en
Crystal structure of the macro ...... rom a unique substrate channel
@nl
prefLabel
Crystal structure of the macro ...... rom a unique substrate channel
@ast
Crystal structure of the macro ...... rom a unique substrate channel
@en
Crystal structure of the macro ...... rom a unique substrate channel
@nl
P2093
P2860
P356
P1476
Crystal structure of the macro ...... rom a unique substrate channel
@en
P2093
J Krucinski
L J Miercke
P G Foster
R M Stroud
P2860
P304
P356
10.1073/PNAS.011399198
P407
P577
2001-12-18T00:00:00Z