Structure of the GCN5 histone acetyltransferase bound to a bisubstrate inhibitor
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The human monocytic leukemia zinc finger histone acetyltransferase domain contains DNA-binding activity implicated in chromatin targetingStructural basis for substrate specificity and catalysis of human histone acetyltransferase 1Structure and Functional Diversity of GCN5-Related N-Acetyltransferases (GNAT)Structure and mechanism of non-histone protein acetyltransferase enzymesProtein lysine acetylation by p300/CBPMolecular basis for age-dependent microtubule acetylation by tubulin acetyltransferase.Mechanistic and Structural Analysis of Human Spermidine/Spermine N 1 -Acetyltransferase † , ‡Crystal structure of RimI fromSalmonella typhimurium LT2, the GNAT responsible for Nα-acetylation of ribosomal protein S18Structure of the complex of Neisseria gonorrhoeae N-acetyl-l-glutamate synthase with a bound bisubstrate analogHistone acetyltransferases and histone deacetylases in B- and T-cell development, physiology and malignancyA random sequential mechanism of aminoglycoside acetylation by Mycobacterium tuberculosis Eis proteinVirtual ligand screening of the p300/CBP histone acetyltransferase: identification of a selective small molecule inhibitorWriters and readers of histone acetylation: structure, mechanism, and inhibitionHistone acetyltransferase activity of p300 is required for transcriptional repression by the promyelocytic leukemia zinc finger protein.Small molecule inhibitors of histone acetyltransferases as epigenetic tools and drug candidates.Processing mechanism and substrate selectivity of the core NuA4 histone acetyltransferase complex.Sirtuin 1 (SIRT1) deacetylase activity is not required for mitochondrial biogenesis or peroxisome proliferator-activated receptor-gamma coactivator-1alpha (PGC-1alpha) deacetylation following endurance exercise.Metabolic Regulation of Histone Acetyltransferases by Endogenous Acyl-CoA Cofactors.PCAF regulates the stability of the transcriptional regulator and cyclin-dependent kinase inhibitor p27 Kip1.Chemistry of acetyl transfer by histone modifying enzymes: structure, mechanism and implications for effector design.Structural basis for acyl-group discrimination by human Gcn5L2Chemical probes for histone-modifying enzymesHistone acetyltransferase inhibitors and preclinical studies.Regulation of a Protein Acetyltransferase in Myxococcus xanthus by the Coenzyme NADP.Chemical Biology for Investigating Epigenetic Functions of Lysine Acetyltransferases (KATs).Identification of structural features of 2-alkylidene-1,3-dicarbonyl derivatives that induce inhibition and/or activation of histone acetyltransferases KAT3B/p300 and KAT2B/PCAF.p300/CBP-associated factor drives DEK into interchromatin granule clusters.Structural Basis of Eco1-Mediated Cohesin Acetylation.Characterization, localization, essentiality, and high-resolution crystal structure of glucosamine 6-phosphate N-acetyltransferase from Trypanosoma brucei.Probing the reaction coordinate of the p300/CBP histone acetyltransferase with bisubstrate analogs.Involvement of Hat1p (Kat1p) catalytic activity and subcellular localization in telomeric silencing.Generating enzyme and radical-mediated bisubstrates as tools for investigating Gcn5-related N-acetyltransferases.Structural and functional features of lysine acetylation of plant and animal tubulins.KAT2A coupled with the α-KGDH complex acts as a histone H3 succinyltransferase.Discovery of alkyl bis(oxy)dibenzimidamide derivatives as novel protein arginine methyltransferase 1 (PRMT1) inhibitors.
P2860
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P2860
Structure of the GCN5 histone acetyltransferase bound to a bisubstrate inhibitor
description
2002 nî lūn-bûn
@nan
2002 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
@yue
name
Structure of the GCN5 histone acetyltransferase bound to a bisubstrate inhibitor
@ast
Structure of the GCN5 histone acetyltransferase bound to a bisubstrate inhibitor
@en
Structure of the GCN5 histone acetyltransferase bound to a bisubstrate inhibitor
@nl
type
label
Structure of the GCN5 histone acetyltransferase bound to a bisubstrate inhibitor
@ast
Structure of the GCN5 histone acetyltransferase bound to a bisubstrate inhibitor
@en
Structure of the GCN5 histone acetyltransferase bound to a bisubstrate inhibitor
@nl
prefLabel
Structure of the GCN5 histone acetyltransferase bound to a bisubstrate inhibitor
@ast
Structure of the GCN5 histone acetyltransferase bound to a bisubstrate inhibitor
@en
Structure of the GCN5 histone acetyltransferase bound to a bisubstrate inhibitor
@nl
P2093
P2860
P3181
P356
P1476
Structure of the GCN5 histone acetyltransferase bound to a bisubstrate inhibitor
@en
P2093
Arienne N Poux
Cheol M Kim
Marek Cebrat
Philip A Cole
P2860
P304
P3181
P356
10.1073/PNAS.222373899
P407
P577
2002-10-29T00:00:00Z