An extensively associated dimer in the structure of the C713S mutant of the TIR domain of human TLR2
about
The structural biology of Toll-like receptorsPlant NBS-LRR proteins in pathogen sensing and host defenseThe crystal structure of the human toll-like receptor 10 cytoplasmic domain reveals a putative signaling dimerMolecular Mimicry in Innate Immunity: CRYSTAL STRUCTURE OF A BACTERIAL TIR DOMAINCrystal Structure of IL-17 Receptor B SEFIR DomainMolecular mechanisms for the subversion of MyD88 signaling by TcpC from virulent uropathogenic Escherichia coliStructures and interface mapping of the TIR domain-containing adaptor molecules involved in interferon signalingCrystal Structures of the Toll/Interleukin-1 Receptor (TIR) Domains from the Brucella Protein TcpB and Host Adaptor TIRAP Reveal Mechanisms of Molecular MimicryIn silico approach to inhibition of signaling pathways of Toll-like receptors 2 and 4 by ST2LStructural and functional evidence for the role of the TLR2 DD loop in TLR1/TLR2 heterodimerization and signalingDetails of Toll-like receptor:adapter interaction revealed by germ-line mutagenesis.A structural model of the E. coli PhoB dimer in the transcription initiation complex.Toll-like receptors: structural pieces of a curve-shaped puzzle.Novel mutations in TLR genes cause hyporesponsiveness to Mycobacterium avium subsp. paratuberculosis infection.Targeting TLR4 signaling by TLR4 Toll/IL-1 receptor domain-derived decoy peptides: identification of the TLR4 Toll/IL-1 receptor domain dimerization interface.Gene polymorphisms in pattern recognition receptors and susceptibility to idiopathic recurrent vulvovaginal candidiasisCrystal structure of the Toll/interleukin-1 receptor domain of human IL-1RAPL.Toll-like receptors as a target of food-derived anti-inflammatory compoundsDivergent roles of amino acid residues inside and outside the BB loop affect human Toll-like receptor (TLR)2/2, TLR2/1 and TLR2/6 responsiveness.The dsRNA binding site of human Toll-like receptor 3.TIR domain-containing adaptor SARM is a late addition to the ongoing microbe-host dialog.Inhibition of TLR2 signaling by small molecule inhibitors targeting a pocket within the TLR2 TIR domainInnate immune recognition of nucleic acids.Cell-penetrating TIR BB loop decoy peptides a novel class of TLR signaling inhibitors and a tool to study topology of TIR-TIR interactions.Structure, function and regulation of the Toll/IL-1 receptor adaptor proteins.Functional cell permeable motifs within medically relevant proteins.Auranofin, as an anti-rheumatic gold compound, suppresses LPS-induced homodimerization of TLR4.Toll-like receptors in skin infections and inflammatory diseases.Inflammasome-mediated secretion of IL-1β in human monocytes through TLR2 activation; modulation by dietary fatty acids.Fatty acids modulate Toll-like receptor 4 activation through regulation of receptor dimerization and recruitment into lipid rafts in a reactive oxygen species-dependent manner.Similar Structures but Different Roles - An Updated Perspective on TLR Structures.Structure and function of Toll/interleukin-1 receptor/resistance protein (TIR) domains.Structures and recognition modes of toll-like receptors.Garlic (Allium sativum) extract inhibits lipopolysaccharide-induced Toll-like receptor 4 dimerization.Structural basis of TIR-domain-assembly formation in MAL- and MyD88-dependent TLR4 signaling.Identification of binding sites for myeloid differentiation primary response gene 88 (MyD88) and Toll-like receptor 4 in MyD88 adapter-like (Mal).Modeling of the Toll-like receptor 3 and a putative Toll-like receptor 3 antagonist encoded by the African swine fever virus.Interactive sites in the MyD88 Toll/interleukin (IL) 1 receptor domain responsible for coupling to the IL1beta signaling pathway.Identification of interaction sites for dimerization and adapter recruitment in Toll/interleukin-1 receptor (TIR) domain of Toll-like receptor 4.An in silico approach towards the identification of novel inhibitors of the TLR-4 signaling pathway.
P2860
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P2860
An extensively associated dimer in the structure of the C713S mutant of the TIR domain of human TLR2
description
2002 nî lūn-bûn
@nan
2002 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
An extensively associated dime ...... f the TIR domain of human TLR2
@ast
An extensively associated dime ...... f the TIR domain of human TLR2
@en
An extensively associated dime ...... f the TIR domain of human TLR2
@nl
type
label
An extensively associated dime ...... f the TIR domain of human TLR2
@ast
An extensively associated dime ...... f the TIR domain of human TLR2
@en
An extensively associated dime ...... f the TIR domain of human TLR2
@nl
prefLabel
An extensively associated dime ...... f the TIR domain of human TLR2
@ast
An extensively associated dime ...... f the TIR domain of human TLR2
@en
An extensively associated dime ...... f the TIR domain of human TLR2
@nl
P2093
P3181
P1476
An extensively associated dime ...... f the TIR domain of human TLR2
@en
P2093
P304
P3181
P356
10.1016/S0006-291X(02)02581-0
P407
P577
2002-11-29T00:00:00Z