Crystal structures of reversible ketone-Based inhibitors of the cysteine protease cruzain

Crystal structures of reversible ketone-Based inhibitors of the cysteine protease cruzain

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http://www.wikidata.org/entity/Q27640115
Vinyl Sulfones as Antiparasitic Agents and a Structural Basis for Drug DesignCrystal structure of the parasite inhibitor chagasin in complex with papain allows identification of structural requirements for broad reactivity and specificity determinants for target proteasesIdentification and Optimization of Inhibitors of Trypanosomal Cysteine Proteases: Cruzain, Rhodesain, and TbCatBNonpeptidic Tetrafluorophenoxymethyl Ketone Cruzain Inhibitors as Promising New Leads for Chagas Disease ChemotherapyIn Vitro and In Vivo Studies of the Trypanocidal Properties of WRR-483 against Trypanosoma cruziThe Potential of Secondary Metabolites from Plants as Drugs or Leads against Protozoan Neglected Diseases-Part III: In-Silico Molecular Docking InvestigationsMethods for the synthesis of polyhydroxylated piperidines by diastereoselective dihydroxylation: exploitation in the two-directional synthesis of aza-C-linked disaccharide derivatives.Computational identification of uncharacterized cruzain binding sitesNovel cruzain inhibitors for the treatment of Chagas' disease.Trypanocidal drugs: mechanisms, resistance and new targets.Predicting binding modes of reversible peptide-based inhibitors of falcipain-2 consistent with structure-activity relationships.α-ketoheterocycles as inhibitors of Leishmania mexicana cysteine protease CPB.The propeptide of cruzipain--a potent selective inhibitor of the trypanosomal enzymes cruzipain and brucipain, and of the human enzyme cathepsin F.Divergent modes of enzyme inhibition in a homologous structure-activity series.Synthesis of densely functionalised 5-halogen-1,3-oxazin-2-ones by halogen-mediated regioselective cyclisation of N-Cbz-protected propargylic amines: a combined experimental and theoretical study.Structural and functional characterization of Falcipain-2, a hemoglobinase from the malarial parasite Plasmodium falciparum.Identification of levothyroxine antichagasic activity through computer-aided drug repurposing
P2860

Crystal structures of reversible ketone-Based inhibitors of the cysteine protease cruzain

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http://www.wikidata.org/entity/Q27640115
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2003 nî lūn-bûn
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2003 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Crystal structures of reversible ketone-Based inhibitors of the cysteine protease cruzain
@ast
Crystal structures of reversible ketone-Based inhibitors of the cysteine protease cruzain
@en
Crystal structures of reversible ketone-Based inhibitors of the cysteine protease cruzain
@nl
type
label
Crystal structures of reversible ketone-Based inhibitors of the cysteine protease cruzain
@ast
Crystal structures of reversible ketone-Based inhibitors of the cysteine protease cruzain
@en
Crystal structures of reversible ketone-Based inhibitors of the cysteine protease cruzain
@nl
prefLabel
Crystal structures of reversible ketone-Based inhibitors of the cysteine protease cruzain
@ast
Crystal structures of reversible ketone-Based inhibitors of the cysteine protease cruzain
@en
Crystal structures of reversible ketone-Based inhibitors of the cysteine protease cruzain
@nl
P1433
P1476
P2093
P304
P31
P356
P407
P433
P478
P577
P698
P921
P356
P1433
P1476
Crystal structures of reversible ketone-Based inhibitors of the cysteine protease cruzain
@en
P2093
P304
P31
P356
10.1016/S0968-0896(02)00427-3
P407
P433
P478
P577
P698
P921