The crystal structure of dipeptidyl peptidase IV (CD26) reveals its functional regulation and enzymatic mechanism
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Does human attractin have DP4 activity?One site mutation disrupts dimer formation in human DPP-IV proteinsStructure of glutamate carboxypeptidase II, a drug target in neuronal damage and prostate cancerRegulation of glucose homeostasis by GLP-1DPP4 in DiabetesAnti-infective immunoadhesins from plants.Crystal structure of human dipeptidyl peptidase IV in complex with a decapeptide reveals details on substrate specificity and tetrahedral intermediate formationDipeptidyl Aminopeptidase IV from Stenotrophomonas maltophilia Exhibits Activity against a Substrate Containing a 4-Hydroxyproline ResidueInduced-fit mechanism for prolyl endopeptidase.Structural definition and substrate specificity of the S28 protease family: the crystal structure of human prolylcarboxypeptidaseHybrid molecular structure of the giant protease tripeptidyl peptidase IIStructure and Catalysis of Acylaminoacyl Peptidase: CLOSED AND OPEN SUBUNITS OF A DIMER OLIGOPEPTIDASEStructures of Human DPP7 Reveal the Molecular Basis of Specific Inhibition and the Architectural Diversity of Proline-Specific PeptidasesA Self-compartmentalizing Hexamer Serine Protease from Pyrococcus Horikoshii: SUBSTRATE SELECTION ACHIEVED THROUGH MULTIMERIZATIONS46 Peptidases are the First Exopeptidases to be Members of Clan PACatalytically distinct states captured in a crystal lattice: the substrate-bound and scavenger states of acylaminoacyl peptidase and their implications for functionalityAnagliptin, a potent dipeptidyl peptidase IV inhibitor: its single-crystal structure and enzyme interactionsEffects of Glycosylation on the Enzymatic Activity and Mechanisms of ProteasesRegulation of Chemokine Activity - A Focus on the Role of Dipeptidyl Peptidase IV/CD26Recent Advances in Dipeptidyl-Peptidase-4 Inhibition Therapy: Lessons from the Bench and Clinical TrialsIR laser-induced protein crystal transformation.Selective inhibition of fibroblast activation protein protease based on dipeptide substrate specificity.Molecular cloning of the precursor polypeptide of mastoparan B and its putative processing enzyme, dipeptidyl peptidase IV, from the black-bellied hornet, Vespa basalis.Marine Peptides as Potential Agents for the Management of Type 2 Diabetes Mellitus-A ProspectIsolation of dipeptidyl peptidase IV (DP 4) isoforms from porcine kidney by preparative isoelectric focusing to improve crystallization.Sitagliptin (MK0431) inhibition of dipeptidyl peptidase IV decreases nonobese diabetic mouse CD4+ T-cell migration through incretin-dependent and -independent pathways.The emergence of the Middle East respiratory syndrome coronavirusVariants of asthma and chronic obstructive pulmonary disease genes and lung function decline in aging.Increasing the X-ray diffraction power of protein crystals by dehydration: the case of bovine serum albumin and a survey of literature data.(R)-1-[(S)-(3-Cyano-thio-morpholino)carbon-yl]-2-methyl-propyl-aminium chloride dihydratePreclinical development of dipeptidyl peptidase IV inhibitor alogliptin: a brief overview.The dimeric transmembrane domain of prolyl dipeptidase DPP-IV contributes to its quaternary structure and enzymatic activities.Investigation of the dimer interface and substrate specificity of prolyl dipeptidase DPP8.Comparative genome analysis of Prevotella intermedia strain isolated from infected root canal reveals features related to pathogenicity and adaptation.The metabolic serine hydrolases and their functions in mammalian physiology and disease.Crystallization and preliminary crystallographic analysis of porcine acylaminoacyl peptidase.Molecular machines for protein degradation.The isoenzyme of glutaminyl cyclase is an important regulator of monocyte infiltration under inflammatory conditions.Therapeutic assessment of glucagon-like peptide-1 agonists compared with dipeptidyl peptidase IV inhibitors as potential antidiabetic drugs.Inhibitor selectivity in the clinical application of dipeptidyl peptidase-4 inhibition.
P2860
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P2860
The crystal structure of dipeptidyl peptidase IV (CD26) reveals its functional regulation and enzymatic mechanism
description
2003 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
article scientifique (publié 2003/04/29)
@fr
articolo scientifico (pubblicato il 2003/04/29)
@it
artigo científico (publicado na 2003/04/29)
@pt
artículu científicu espublizáu en 2003
@ast
im April 2003 veröffentlichter wissenschaftlicher Artikel
@de
scientific article (publication date: 29 April 2003)
@en
vedecký článok (publikovaný 2003/04/29)
@sk
videnskabelig artikel (udgivet 2003/04/29)
@da
name
The crystal structure of dipep ...... lation and enzymatic mechanism
@ast
The crystal structure of dipep ...... lation and enzymatic mechanism
@en
The crystal structure of dipep ...... lation and enzymatic mechanism
@nl
type
label
The crystal structure of dipep ...... lation and enzymatic mechanism
@ast
The crystal structure of dipep ...... lation and enzymatic mechanism
@en
The crystal structure of dipep ...... lation and enzymatic mechanism
@nl
prefLabel
The crystal structure of dipep ...... lation and enzymatic mechanism
@ast
The crystal structure of dipep ...... lation and enzymatic mechanism
@en
The crystal structure of dipep ...... lation and enzymatic mechanism
@nl
P2093
P2860
P50
P3181
P356
P1476
The crystal structure of dipep ...... lation and enzymatic mechanism
@en
P2093
Leona Wagner
Michael Engel
Michael Wermann
Reiner Kiefersauer
Robert Huber
Torsten Hoffmann
Ulrich Heiser
P2860
P304
P3181
P356
10.1073/PNAS.0230620100
P407
P577
2003-04-29T00:00:00Z