Crystal structure and carbohydrate-binding properties of the human cartilage glycoprotein-39
about
The synovial proteome: analysis of fibroblast-like synoviocytesRole of YKL-40 in the angiogenesis, radioresistance, and progression of glioblastomaStructure of human stabilin-1 interacting chitinase-like protein (SI-CLP) reveals a saccharide-binding cleft with lower sugar-binding selectivityInflammatory cytokines induce production of CHI3L1 by articular chondrocytesA YKL-40-neutralizing antibody blocks tumor angiogenesis and progression: a potential therapeutic agent in cancersPotential role of chitinases and chitin-binding proteins in host-microbial interactions during the development of intestinal inflammationInhibitory activity of YKL-40 in mammary epithelial cell differentiation and polarization induced by lactogenic hormones: a role in mammary tissue involutionStructure of the buffalo secretory signalling glycoprotein at 2.8 Å resolutionStructural investigation of a novel N-acetyl glucosamine binding chi-lectin which reveals evolutionary relationship with class III chitinasesNew insights into the enzymatic mechanism of human chitotriosidase (CHIT1) catalytic domain by atomic resolution X-ray diffraction and hybrid QM/MMSequence and structural analysis of the chitinase insertion domain reveals two conserved motifs involved in chitin-bindingCarbohydrate-binding motif in chitinase 3-like 1 (CHI3L1/YKL-40) specifically activates Akt signaling pathway in colonic epithelial cellsSerum YKL-40 concentrations in newly diagnosed multiple myeloma patients and YKL-40 expression in malignant plasma cells.YKL-40, a marker of simian immunodeficiency virus encephalitis, modulates the biological activity of basic fibroblast growth factor.YKL-40 as a novel factor associated with inflammation and catabolic mechanisms in osteoarthritic jointsAnimal models of colitis-associated carcinogenesis.Chitinase family GH18: evolutionary insights from the genomic history of a diverse protein family.Structural and thermodynamic insights into chitooligosaccharide binding to human cartilage chitinase 3-like protein 2 (CHI3L2 or YKL-39).Plasma YKL-40 and all-cause mortality in patients with chronic obstructive pulmonary disease.Antibody directed against human YKL-40 increases tumor volume in a human melanoma xenograft model in scid mice.Visualisation of cyclic and multi-branched molecules with VMD.Keeping track of the growing number of biological functions of chitin and its interaction partners in biomedical researchBreast cancer expression of YKL-40 correlates with tumour grade, poor differentiation, and other cancer markers.Two closely related human members of chitinase-like family, CHI3L1 and CHI3L2, activate ERK1/2 in 293 and U373 cells but have the different influence on cell proliferation.Helminth parasites--masters of regulation.Family 18 chitolectins: comparison of MGP40 and HUMGP39Chitin elicits CCL2 from airway epithelial cells and induces CCR2-dependent innate allergic inflammation in the lung.Role of chitotriosidase (chitinase 1) under normal and disease conditions.Is YKL-40 a new therapeutic target in cancer?Serum YKL-40 Levels in Patients with Gastric CancerGene expression and activity of cartilage degrading glycosidases in human rheumatoid arthritis and osteoarthritis synovial fibroblasts.Human chitinases and chitinase-like proteins as indicators for inflammation and cancerYKL-40-A Protein in the Field of Translational Medicine: A Role as a Biomarker in Cancer Patients?Chitin, chitinases and chitinase-like proteins in allergic inflammation and tissue remodeling.Anti-YKL-40 antibody and ionizing irradiation synergistically inhibit tumor vascularization and malignancy in glioblastoma.Novel methylxanthine derivative-mediated anti-inflammatory effects in inflammatory bowel disease.Plasma YKL-40: a potential new cancer biomarker?YKL-40--an emerging biomarker in cardiovascular disease and diabetes.CHI3L1 plays a role in cancer through enhanced production of pro-inflammatory/pro-tumorigenic and angiogenic factors.Elevated YKL-40 expression is associated with a poor prognosis in breast cancer patients.
P2860
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P2860
Crystal structure and carbohydrate-binding properties of the human cartilage glycoprotein-39
description
2003 nî lūn-bûn
@nan
2003 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Crystal structure and carbohyd ...... uman cartilage glycoprotein-39
@ast
Crystal structure and carbohyd ...... uman cartilage glycoprotein-39
@en
Crystal structure and carbohyd ...... uman cartilage glycoprotein-39
@nl
type
label
Crystal structure and carbohyd ...... uman cartilage glycoprotein-39
@ast
Crystal structure and carbohyd ...... uman cartilage glycoprotein-39
@en
Crystal structure and carbohyd ...... uman cartilage glycoprotein-39
@nl
prefLabel
Crystal structure and carbohyd ...... uman cartilage glycoprotein-39
@ast
Crystal structure and carbohyd ...... uman cartilage glycoprotein-39
@en
Crystal structure and carbohyd ...... uman cartilage glycoprotein-39
@nl
P2093
P2860
P356
P1476
Crystal structure and carbohyd ...... uman cartilage glycoprotein-39
@en
P2093
Bauke W Dijkstra
Fabrizia Fusetti
Kor H Kalk
Tjaard Pijning
P2860
P304
P356
10.1074/JBC.M303137200
P407
P577
2003-09-26T00:00:00Z