Crystallographic studies on the reaction of isopenicillin N synthase with an unsaturated substrate analogue
about
The crystal structure of an LLL-configured depsipeptide substrate analogue bound to isopenicillin N synthaseIsopenicillin N synthase binds δ-(L-α-aminoadipoyl)-L-cysteinyl-D-thia-allo-isoleucine through both sulfur atomsThe interaction of isopenicillin N synthase with homologated substrate analogues δ-(L-α-aminoadipoyl)-L-homocysteinyl-D-Xaa characterised by protein crystallographyThe crystal structure of an isopenicillin N synthase complex with an ethereal substrate analogue reveals water in the oxygen binding siteThe enzymes of β-lactam biosynthesis.Non-heme Fe(IV)-oxo intermediates.Cyclobutanone Analogues of β-Lactam Antibiotics: β-Lactamase Inhibitors with Untapped Potential?Active-site-mediated elimination of hydrogen fluoride from a fluorinated substrate analogue by isopenicillin N synthase.Terminally Truncated Isopenicillin N Synthase Generates a Dithioester Product: Evidence for a Thioaldehyde Intermediate during Catalysis and a New Mode of Reaction for Non-Heme Iron Oxidases.MetalS(3), a database-mining tool for the identification of structurally similar metal sites.Unexpected oxidation of a depsipeptide substrate analogue in crystalline isopenicillin N synthase.
P2860
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P2860
Crystallographic studies on the reaction of isopenicillin N synthase with an unsaturated substrate analogue
description
2003 nî lūn-bûn
@nan
2003 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Crystallographic studies on th ...... unsaturated substrate analogue
@ast
Crystallographic studies on th ...... unsaturated substrate analogue
@en
Crystallographic studies on th ...... unsaturated substrate analogue
@nl
type
label
Crystallographic studies on th ...... unsaturated substrate analogue
@ast
Crystallographic studies on th ...... unsaturated substrate analogue
@en
Crystallographic studies on th ...... unsaturated substrate analogue
@nl
prefLabel
Crystallographic studies on th ...... unsaturated substrate analogue
@ast
Crystallographic studies on th ...... unsaturated substrate analogue
@en
Crystallographic studies on th ...... unsaturated substrate analogue
@nl
P2093
P356
P1476
Crystallographic studies on th ...... unsaturated substrate analogue
@en
P2093
Ian J Clifton
Jack E Baldwin
Peter J Rutledge
Peter L Roach
Robert M Adlington
P304
P356
10.1039/B212270G
P577
2003-05-01T00:00:00Z