The crystal structures of severe acute respiratory syndrome virus main protease and its complex with an inhibitor - Test2 - elhamkhani - TriplyDB

The crystal structures of severe acute respiratory syndrome virus main protease and its complex with an inhibitor

The crystal structures of severe acute respiratory syndrome virus main protease and its complex with an inhibitor

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Molecular advances in the cell biology of SARS-CoV and current disease prevention strategies Respiratory viruses other than influenza virus: impact and therapeutic advances Molecular mechanisms of severe acute respiratory syndrome (SARS)Functional and genetic analysis of coronavirus replicase-transcriptase proteins Design of wide-spectrum inhibitors targeting coronavirus main proteases Pains and Gains from China's Experiences with Emerging Epidemics: From SARS to H7N9 From SARS to MERS: crystallographic studies on coronaviral proteases enable antiviral drug design Localization and Membrane Topology of Coronavirus Nonstructural Protein 4: Involvement of the Early Secretory Pathway in Replication Functional Characterization of the Cleavage Specificity of the Sapovirus Chymotrypsin-Like Protease Novel β-Barrel Fold in the Nuclear Magnetic Resonance Structure of the Replicase Nonstructural Protein 1 from the Severe Acute Respiratory Syndrome Coronavirus Mutation of Gly-11 on the dimer interface results in the complete crystallographic dimer dissociation of severe acute respiratory syndrome coronavirus 3C-like protease: crystal structure with molecular dynamics simulations Structural basis of mercury- and zinc-conjugated complexes as SARS-CoV 3C-like protease inhibitors Structures of Two Coronavirus Main Proteases: Implications for Substrate Binding and Antiviral Drug Design Mechanism for Controlling the Dimer-Monomer Switch and Coupling Dimerization to Catalysis of the Severe Acute Respiratory Syndrome Coronavirus 3C-Like Protease Structure of the Main Protease from a Global Infectious Human Coronavirus, HCoV-HKU1 Crystal Structures of Two Coronavirus ADP-Ribose-1''-Monophosphatases and Their Complexes with ADP-Ribose: a Systematic Structural Analysis of the Viral ADRP Domain C-terminal domain of sars-CoV main protease can form a 3d domain-swapped dimer The SARS-Unique Domain (SUD) of SARS Coronavirus Contains Two Macrodomains That Bind G-Quadruplexes Mutation of Asn28 Disrupts the Dimerization and Enzymatic Activity of SARS 3CL pro Three-dimensional domain swapping as a mechanism to lock the active conformation in a super-active octamer of SARS-CoV main protease Enterovirus 71 and Coxsackievirus A16 3C Proteases: Binding to Rupintrivir and Their Substrates and Anti-Hand, Foot, and Mouth Disease Virus Drug Design Discovery, synthesis, and structure-based optimization of a series of N-(tert-butyl)-2-(N-arylamido)-2-(pyridin-3-yl) acetamides (ML188) as potent noncovalent small molecule inhibitors of the severe acute respiratory syndrome coronavirus (SARS-CoV)Mechanism for controlling the monomer-dimer conversion of SARS coronavirus main protease X-ray structure and inhibition of the feline infectious peritonitis virus 3C-like protease: Structural implications for drug design Severe acute respiratory syndrome coronavirus as an agent of emerging and reemerging infection Genome-wide analysis of protein-protein interactions and involvement of viral proteins in SARS-CoV replication Dynamically-driven inactivation of the catalytic machinery of the SARS 3C-like protease by the N214A mutation on the extra domain Life sciences and biotechnology in China.Characterization of Bafinivirus main protease autoprocessing activities.Characterization of a torovirus main proteinase Mutagenesis analysis of the nsp4 main proteinase reveals determinants of arterivirus replicase polyprotein autoprocessing.Anti-SARS coronavirus agents: a patent review (2008 - present).Evaluation of metal-conjugated compounds as inhibitors of 3CL protease of SARS-CoV.Rapid peptide-based screening on the substrate specificity of severe acute respiratory syndrome (SARS) coronavirus 3C-like protease by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.An efficient method for the synthesis of peptide aldehyde libraries employed in the discovery of reversible SARS coronavirus main protease (SARS-CoV Mpro) inhibitors.Severe acute respiratory syndrome (SARS): development of diagnostics and antivirals.Analysis of murine hepatitis virus strain A59 temperature-sensitive mutant TS-LA6 suggests that nsp10 plays a critical role in polyprotein processing SARS-coronavirus replication/transcription complexes are membrane-protected and need a host factor for activity in vitro A computational analysis of SARS cysteine proteinase-octapeptide substrate interaction: implication for structure and active site binding mechanism Profiling of substrate specificity of SARS-CoV 3CL

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P2860

The crystal structures of severe acute respiratory syndrome virus main protease and its complex with an inhibitor

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2003 nî lūn-bûn

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2003 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

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2003 թվականի նոյեմբերին հրատարակված գիտական հոդված

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2003年の論文

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2003年論文

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2003年論文

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2003年論文

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2003年論文

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2003年論文

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2003年论文

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The crystal structures of seve ...... its complex with an inhibitor

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The crystal structures of seve ...... its complex with an inhibitor

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The crystal structures of seve ...... its complex with an inhibitor

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The crystal structures of seve ...... its complex with an inhibitor

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George F Gao

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Hai Pang

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Kanchan Anand

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Lei Sun

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Lijuan Mo

http://www.w3.org/2001/XMLSchema#string

Sheng Ye

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Yi Ding

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Yiwei Liu

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Zhe Zhou

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Zhiyong Lou

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P2860

Improved methods for building protein models in electron density maps and the location of errors in these models

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

PROCHECK: a program to check the stereochemical quality of protein structures

Processing of X-ray diffraction data collected in oscillation mode

Structure of coronavirus main proteinase reveals combination of a chymotrypsin fold with an extra alpha-helical domain.

Coronavirus main proteinase (3CLpro) structure: basis for design of anti-SARS drugs

Solvent content of protein crystals

Coronavirus as a possible cause of severe acute respiratory syndrome

Characterization of a novel coronavirus associated with severe acute respiratory syndrome

Identification of a novel coronavirus in patients with severe acute respiratory syndrome

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23

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100

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Rolf Hilgenfeld

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2003-11-11T00:00:00Z

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14585926

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severe acute respiratory syndrome coronavirus

3C-like proteinase [SARS-Cov]

crystal structure

structural biology

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263746

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