Structure of a nucleotide-bound Clp1-Pcf11 polyadenylation factor
about
Human CLP1 mutations alter tRNA biogenesis, affecting both peripheral and central nervous system functionCLP1 founder mutation links tRNA splicing and maturation to cerebellar development and neurodegenerationDisengaging polymerase: terminating RNA polymerase II transcription in budding yeastThe structure of the CstF-77 homodimer provides insights into CstF assemblyCrystal Structure of the HEAT Domain from the Pre-mRNA Processing Factor SymplekinCrystal structure of the 25 kDa subunit of human cleavage factor ImStructure of the Rna15 RRM-RNA complex reveals the molecular basis of GU specificity in transcriptional 3'-end processing factorsMolecular recognition betweenEscherichia colienolase and ribonuclease EStructural and Biochemical Analysis of the Phosphate Donor Specificity of the Polynucleotide Kinase Component of the Bacterial Pnkp•Hen1 RNA Repair SystemRole of the RNA/DNA kinase Grc3 in transcription termination by RNA polymerase IStructural biology of poly(A) site definitionArabidopsis CLP1-SIMILAR PROTEIN3, an ortholog of human polyadenylation factor CLP1, functions in gametophyte, embryo, and postembryonic development.Delineating the structural blueprint of the pre-mRNA 3'-end processing machinery.The P-loop domain of yeast Clp1 mediates interactions between CF IA and CPF factors in pre-mRNA 3' end formation.Coupled RNA polymerase II transcription and 3' end formation with yeast whole-cell extracts.Roles of fission yeast Grc3 protein in ribosomal RNA processing and heterochromatic gene silencingReconstitution of CF IA from overexpressed subunits reveals stoichiometry and provides insights into molecular topology.An essential role for Clp1 in assembly of polyadenylation complex CF IA and Pol II transcription termination.The interaction of Pcf11 and Clp1 is needed for mRNA 3'-end formation and is modulated by amino acids in the ATP-binding site.The export factor Yra1 modulates mRNA 3' end processing.Protein factors in pre-mRNA 3'-end processing.Characterization of a thermostable archaeal polynucleotide kinase homologous to human Clp1.An investigation into the role of ATP in the mammalian pre-mRNA 3' cleavage reactionGenome-Wide Analysis of Polyadenylation Events in Schmidtea mediterraneaStructure and function of pre-mRNA 5'-end capping quality control and 3'-end processing.CLP1 as a novel player in linking tRNA splicing to neurodegenerative disorders.Cotranscriptional recruitment of the mRNA export factor Yra1 by direct interaction with the 3' end processing factor Pcf11.Molecular architecture of the human pre-mRNA 3' processing complex.Human RNA 5'-kinase (hClp1) can function as a tRNA splicing enzyme in vivo.Mammalian 2',3' cyclic nucleotide phosphodiesterase (CNP) can function as a tRNA splicing enzyme in vivo.Distinct roles of Pcf11 zinc-binding domains in pre-mRNA 3'-end processing.Grc3 programs the essential endoribonuclease Las1 for specific RNA cleavage.The C terminus of Pcf11 forms a novel zinc-finger structure that plays an essential role in mRNA 3'-end processing.Characterization of the Molecular Crosstalk within the Essential Grc3/Las1 pre-rRNA Processing Complex.Characterization of the Saccharomyces cerevisiae ATP-Interactome using the iTRAQ-SPROX Technique.Arabidopsis PCFS4, a homologue of yeast polyadenylation factor Pcf11p, regulates FCA alternative processing and promotes flowering time.
P2860
Q24295194-EF9B28F2-1255-400E-9CA7-17E765577488Q24295268-208CA233-D27F-40AB-82B2-B4E6D71E7857Q26851212-CAD39329-FBDE-4468-90A6-56500A422A2BQ27646266-D7F723DB-E914-42DF-926D-F624F98E2355Q27646447-490D07E8-A87B-4CC5-B5B3-52E6F6E2D8EFQ27650479-08976BD4-8622-41BD-88AE-BB33E9BC4386Q27659137-B9D3EB73-BC9F-45DC-9562-6D0635C2FEABQ27664342-99118039-6BE3-4A41-87F4-E0919EB83757Q27678388-664AB436-87B0-4B2E-A709-12FD3AD9C53FQ27935444-D1230F66-9DAA-4C28-BDC7-219EA7898FBCQ28245082-3E6A7C98-C954-4ED1-B082-C50E2AB7FEC5Q33346234-46E2F9F7-7690-4FCA-BB19-2E54E07E20FFQ33602636-4F981E09-14F1-4E9C-BB58-07714332F70EQ34117256-BB64CE3E-B34B-4CAC-BD37-793AF4B18584Q34210432-B0C065B9-014B-44F7-9421-D4981D558F12Q34869030-2A0BC182-A6B3-433D-BA2D-6D741BAC5710Q35604752-0E006CB5-17E8-4C16-89D5-4873846FB5DEQ35740539-B7EEBB5E-B8DB-4784-8317-5AE575C45268Q35740543-39AB3227-B006-4617-AA96-DC3785B5DCC5Q35838270-40FA08C1-2A98-4A14-8625-67EDE89A9646Q37044967-A965D46A-9D4D-4B58-9D7B-B3234B86653DQ37168938-DE370CD5-E5A5-44AF-84DD-B14530F156A3Q37291806-F710ED65-AFA9-4B3D-A681-859F1D764B25Q37347972-D3E15D0D-7D8B-4F8C-8486-D815875BCCE0Q38195095-A729D111-EC7D-4A08-A2DF-B20F5280139FQ38241769-F1A5624C-9156-4FC0-BCFD-E2770C3E0BFBQ41920187-D024D34C-7E74-44E6-A47F-47AB4AF97542Q42418612-59BC3B84-DBC2-414E-8BCF-4FC9A5238067Q42418724-AC0366C9-64EC-49B2-B3C4-5247AEA79B9EQ42971555-C491D709-D115-4D5E-9B9F-7D26BF25A342Q47118808-EE15EA0F-7D77-4762-8F24-1BE87429216EQ48220478-FF158C97-6372-4D3D-8663-88C78A128C5CQ49332210-4753BD66-21DE-4126-AB53-D46B5650CC9BQ50026268-FFD45A20-AED5-4782-ACAC-48E6345FFF8CQ50916614-684BEEFB-1512-451B-95C2-AF68F77CCC81Q53496094-EB0ACB65-FAD3-47EE-ACA0-FAACCD54059E
P2860
Structure of a nucleotide-bound Clp1-Pcf11 polyadenylation factor
description
2007 nî lūn-bûn
@nan
2007 թուականին հրատարակուած գիտական յօդուած
@hyw
2007 թվականին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Structure of a nucleotide-bound Clp1-Pcf11 polyadenylation factor
@ast
Structure of a nucleotide-bound Clp1-Pcf11 polyadenylation factor
@en
Structure of a nucleotide-bound Clp1-Pcf11 polyadenylation factor
@nl
type
label
Structure of a nucleotide-bound Clp1-Pcf11 polyadenylation factor
@ast
Structure of a nucleotide-bound Clp1-Pcf11 polyadenylation factor
@en
Structure of a nucleotide-bound Clp1-Pcf11 polyadenylation factor
@nl
prefLabel
Structure of a nucleotide-bound Clp1-Pcf11 polyadenylation factor
@ast
Structure of a nucleotide-bound Clp1-Pcf11 polyadenylation factor
@en
Structure of a nucleotide-bound Clp1-Pcf11 polyadenylation factor
@nl
P2093
P2860
P3181
P356
P1476
Structure of a nucleotide-bound Clp1-Pcf11 polyadenylation factor
@en
P2093
Barbara Beuth
Christian G Noble
Ian A Taylor
P2860
P3181
P356
10.1093/NAR/GKL1010
P407
P577
2007-01-01T00:00:00Z