Crystallographic and kinetic studies of human mitochondrial acetoacetyl-CoA thiolase: the importance of potassium and chloride ions for its structure and function
about
The sulfur atoms of the substrate CoA and the catalytic cysteine are required for a productive mode of substrate binding in bacterial biosynthetic thiolase, a thioester-dependent enzymeCrystal Structure of a Monomeric Thiolase-Like Protein Type 1 (TLP1) from Mycobacterium smegmatisProtein-Protein Interactions in the -Oxidation Part of the Phenylacetate Utilization Pathway: CRYSTAL STRUCTURE OF THE PaaF-PaaG HYDRATASE-ISOMERASE COMPLEXStructure and Stereospecificity of the Dehydratase Domain from the Terminal Module of the Rifamycin Polyketide SynthaseCrystal structures of SCP2-thiolases of Trypanosomatidae, human pathogens causing widespread tropical diseases: the importance for catalysis of the cysteine of the unique HDCF loopThe crystal structure of human mitochondrial 3-ketoacyl-CoA thiolase (T1): insight into the reaction mechanism of its thiolase and thioesterase activitiesStructural characterization of a mitochondrial 3-ketoacyl-CoA (T1)-like thiolase from Mycobacterium smegmatisThe SCP2-thiolase-like protein (SLP) of Trypanosoma brucei is an enzyme involved in lipid metabolismDevelopment of semi-defined rice straw-based medium for butanol production and its kinetic studyThe inositol 5-phosphatase SHIP2 is an effector of RhoA and is involved in cell polarity and migration.Metabolic biology of 3-methylglutaconic acid-uria: a new perspective.Clonorchis sinensis acetoacetyl-CoA thiolase: identification and characterization of its potential role in surviving in the bile ductEssential role of the donor acyl carrier protein in stereoselective chain translocation to a fully reducing module of the nanchangmycin polyketide synthaseMetabolic annotation of 2-ethylhydracrylic acidIsoprenoid biosynthesis in dandelion latex is enhanced by the overexpression of three key enzymes involved in the mevalonate pathwayStereochemistry of reductions catalyzed by methyl-epimerizing ketoreductase domains of polyketide synthases.Calorie restriction and SIRT3 trigger global reprogramming of the mitochondrial protein acetylome.Quantification of mitochondrial acetylation dynamics highlights prominent sites of metabolic regulationA comprehensive machine-readable view of the mammalian cholesterol biosynthesis pathway.Structural Organization of Enzymes of the Phenylacetate Catabolic Hybrid Pathway.Tetrameric Acetyl-CoA Acetyltransferase 1 Is Important for Tumor Growth.Crystallographic substrate binding studies of Leishmania mexicana SCP2-thiolase (type-2): unique features of oxyanion hole-1.Three Japanese Patients with Beta-Ketothiolase Deficiency Who Share a Mutation, c.431A>C (H144P) in ACAT1 : Subtle Abnormality in Urinary Organic Acid Analysis and Blood Acylcarnitine Analysis Using Tandem Mass Spectrometry.The first case of mitochondrial acetoacetyl-CoA thiolase deficiency identified by expanded newborn metabolic screening in Italy: the importance of an integrated diagnostic approach.Cloning, expression, purification and preliminary X-ray diffraction studies of a putative Mycobacterium smegmatis thiolase.Cloning, expression and purification of an acetoacetyl CoA thiolase from sunflower cotyledon.Downregulation of the acetyl-CoA metabolic network in adipose tissue of obese diabetic individuals and recovery after weight loss.A qualitative description of the peptide sharing between poliovirus and Homo sapiens.Label-free quantitative proteomic analysis reveals potential biomarkers and pathways in renal cell carcinoma.Site-Directed Mutagenesis Study Revealed Three Important Residues in Hc-DAF-22, a Key Enzyme Regulating Diapause of Haemonchus contortus.alpha-methyl-acetoacetyl-CoA + CoA => propionyl-CoA + acetyl-CoACrystal structure of a thiolase from Escherichia coli at 1.8 Å resolution.
P2860
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P2860
Crystallographic and kinetic studies of human mitochondrial acetoacetyl-CoA thiolase: the importance of potassium and chloride ions for its structure and function
description
2007 nî lūn-bûn
@nan
2007 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Crystallographic and kinetic s ...... for its structure and function
@ast
Crystallographic and kinetic s ...... for its structure and function
@en
Crystallographic and kinetic s ...... for its structure and function
@nl
type
label
Crystallographic and kinetic s ...... for its structure and function
@ast
Crystallographic and kinetic s ...... for its structure and function
@en
Crystallographic and kinetic s ...... for its structure and function
@nl
prefLabel
Crystallographic and kinetic s ...... for its structure and function
@ast
Crystallographic and kinetic s ...... for its structure and function
@en
Crystallographic and kinetic s ...... for its structure and function
@nl
P2093
P356
P1433
P1476
Crystallographic and kinetic s ...... for its structure and function
@en
P2093
Antti M Haapalainen
Gitte Meriläinen
Naomi Kondo
Päivi L Pirilä
Rik K Wierenga
Toshiyuki Fukao
P304
P356
10.1021/BI6026192
P407
P577
2007-04-10T00:00:00Z