Convergent chemical synthesis and crystal structure of a 203 amino acid "covalent dimer" HIV-1 protease enzyme molecule
about
X-ray Structure of Snow Flea Antifreeze Protein Determined by Racemic Crystallization of Synthetic Protein EnantiomersProtein conformational dynamics in the mechanism of HIV-1 protease catalysisDesign, total chemical synthesis, and X-ray structure of a protein having a novel linear-loop polypeptide chain topologyOne-pot hydrazide-based native chemical ligation for efficient chemical synthesis and structure determination of toxin Mambalgin-1Total chemical synthesis, refolding, and crystallographic structure of fully active immunophilin calstabin 2 (FKBP12.6)Expanding the chemical toolbox for the synthesis of large and uniquely modified proteins.Chemical and semisynthesis of posttranslationally modified proteins.Peptide and glycopeptide dendrimers and analogous dendrimeric structures and their biomedical applications.Synthesis and folding of a mirror-image enzyme reveals ambidextrous chaperone activity.The early years of retroviral protease crystal structures.Characterization of proteins with wide-angle X-ray solution scattering (WAXS)Convergent chemical synthesis of [lysine(24,38,83)] human erythropoietin.Toward fully synthetic homogeneous beta-human follicle-stimulating hormone (beta-hFSH) with a biantennary N-linked dodecasaccharide. synthesis of beta-hFSH with chitobiose units at the natural linkage sites.Toward homogeneous erythropoietin: chemical synthesis of the Ala1-Gly28 glycopeptide domain by "alanine" ligation.Recent Departures in the Synthesis of Peptides and Glycopeptides.Using peptides to study protein-protein interactions.Through the looking glass--a new world of proteins enabled by chemical synthesis.Enzyme-mediated methodologies for protein modification and bioconjugate synthesis.Sequential native peptide ligation strategies for total chemical protein synthesis.Patchwork protein chemistry: a practitioner's treatise on the advances in synthetic peptide stitchery.Native chemical ligation: a boon to peptide chemistry.Pushing the Boundaries of Chemical Protein Synthesis: The Case of Ubiquitin Chains and Polyubiquitinated Peptides and Proteins.Exploring chemoselective S-to-N acyl transfer reactions in synthesis and chemical biology.t-boc synthesis of huwentoxin-i through native chemical ligation incorporating a trifluoromethanesulfonic acid cleavage strategy.Chemical synthesis and expression of the HIV-1 Rev protein.Total chemical synthesis of the site-selective azide-labeled [I66A]HIV-1 protease.At last: erythropoietin as a single glycoformSynthesis of tumor necrosis factor α for use as a mirror-image phage display targetOptimisation of chemical protein cleavage for erythropoietin semi-synthesis using native chemical ligation.Engineering of therapeutic polypeptides through chemical synthesis: early lessons from human parathyroid hormone and analogues.Revisiting oxytocin through the medium of isonitriles.Evolving the use of peptides as components of biomaterials.Peptide ligation-desulfurization chemistry at arginine.N-sulfanylethylanilide peptide as a crypto-thioester peptide.Mechanistic insight into benzenethiol catalyzed amide bond formations from thioesters and primary amines.Electron-deficient alkynes as cleavable reagents for the modification of cysteine-containing peptides in aqueous medium.Sortase-mediated chemical protein synthesis reveals the bidentate binding of bisphosphorylated p62 with K63 diubiquitin.Hydrogen bonds are a primary driving force for de novo protein folding.Bringing the science of proteins into the realm of organic chemistry: total chemical synthesis of SEP (synthetic erythropoiesis protein).Chemical synthesis of a polypeptide backbone derived from the primary sequence of the cancer protein NY-ESO-1 enabled by kinetically controlled ligation and pseudoprolines.
P2860
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P2860
Convergent chemical synthesis and crystal structure of a 203 amino acid "covalent dimer" HIV-1 protease enzyme molecule
description
2007 nî lūn-bûn
@nan
2007 թուականին հրատարակուած գիտական յօդուած
@hyw
2007 թվականին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Convergent chemical synthesis ...... HIV-1 protease enzyme molecule
@ast
Convergent chemical synthesis ...... HIV-1 protease enzyme molecule
@en
Convergent chemical synthesis ...... HIV-1 protease enzyme molecule
@nl
type
label
Convergent chemical synthesis ...... HIV-1 protease enzyme molecule
@ast
Convergent chemical synthesis ...... HIV-1 protease enzyme molecule
@en
Convergent chemical synthesis ...... HIV-1 protease enzyme molecule
@nl
prefLabel
Convergent chemical synthesis ...... HIV-1 protease enzyme molecule
@ast
Convergent chemical synthesis ...... HIV-1 protease enzyme molecule
@en
Convergent chemical synthesis ...... HIV-1 protease enzyme molecule
@nl
P356
P1476
Convergent chemical synthesis ...... HIV-1 protease enzyme molecule
@en
P2093
Stephen B H Kent
Vladimir Yu Torbeev
P304
P356
10.1002/ANIE.200604087
P407
P577
2007-01-01T00:00:00Z