A designed ankyrin repeat protein evolved to picomolar affinity to Her2 - Test2 - elhamkhani - TriplyDB

A designed ankyrin repeat protein evolved to picomolar affinity to Her2

A designed ankyrin repeat protein evolved to picomolar affinity to Her2

http://www.wikidata.org/entity/Q27644627

about

CD4-specific designed ankyrin repeat proteins are novel potent HIV entry inhibitors with unique characteristics Consensus protein design Toward a magic or imaginary bullet? Ligands for drug targeting to cancer cells: principles, hopes, and challenges Intermolecular biparatopic trapping of ErbB2 prevents compensatory activation of PI3K/AKT via RAS-p110 crosstalk.Conformational change-induced repeat domain expansion regulates Rap phosphatase quorum-sensing signal receptors Asparagine beta-hydroxylation stabilizes the ankyrin repeat domain fold Structural Basis for Exquisite Specificity of Affinity Clamps, Synthetic Binding Proteins Generated through Directed Domain-interface Evolution Structural and functional analysis of phosphorylation-specific binders of the kinase ERK from designed ankyrin repeat protein libraries Development of a generic adenovirus delivery system based on structure-guided design of bispecific trimeric DARPin adapters Structure-Based Rational Design of a Toll-like Receptor 4 (TLR4) Decoy Receptor with High Binding Affinity for a Target Protein Artificial affinity proteins as ligands of immunoglobulins Introducing antigen-binding sites in structural loops of immunoglobulin constant domains: Fc fragments with engineered HER2/neu-binding sites and antibody properties Streamlined protocol for mRNA display Engineering of bispecific affinity proteins with high affinity for ERBB2 and adaptable binding to albumin Targeted Delivery of Deoxycytidine Kinase to Her2-Positive Cells Enhances the Efficacy of the Nucleoside Analog Fludarabine New binding mode to TNF-alpha revealed by ubiquitin-based artificial binding protein Protein-protein interactions and selection: generation of molecule-binding proteins on the basis of tertiary structural information.A community standard format for the representation of protein affinity reagents.NextGen protein design.Her2-specific multivalent adapters confer designed tropism to adenovirus for gene targeting Directed evolution of a three-finger neurotoxin by using cDNA display yields antagonists as well as agonists of interleukin-6 receptor signaling.A modeling analysis of the effects of molecular size and binding affinity on tumor targeting.A rapid, site-selective and efficient route to the dual modification of DARPins.Antiviral activity of recombinant ankyrin targeted to the capsid domain of HIV-1 Gag polyprotein.Highly potent VEGF-A-antagonistic DARPins as anti-angiogenic agents for topical and intravitreal applications.Structural model for the interaction of a designed Ankyrin Repeat Protein with the human epidermal growth factor receptor 2.Designed ankyrin repeat proteins: a new approach to mimic complex antigens for diagnostic purposes?Protein interference applications in cellular and developmental biology using DARPins that recognize GFP and mCherry.DARPins: an efficient targeting domain for lentiviral vectors.Development of the designed ankyrin repeat protein (DARPin) G3 for HER2 molecular imaging.Crystal structure of an antiviral ankyrin targeting the HIV-1 capsid and molecular modeling of the ankyrin-capsid complex.A universal approach to prepare reagents for DNA-assisted protein analysis.Streamlining the Pipeline for Generation of Recombinant Affinity Reagents by Integrating the Affinity Maturation Step.Bispecific designed ankyrin repeat proteins (DARPins) targeting epidermal growth factor receptor inhibit A431 cell proliferation and receptor recycling Receptor-Targeted Nipah Virus Glycoproteins Improve Cell-Type Selective Gene Delivery and Reveal a Preference for Membrane-Proximal Cell Attachment.Beyond Antibodies: Development of a Novel Protein Scaffold Based on Human Chaperonin 10.Designed ankyrin repeat proteins are effective targeting elements for chimeric antigen receptors.Inferring repeat-protein energetics from evolutionary information.Immunocapture strategies in translational proteomics.Enhanced lysis by bispecific oncolytic measles viruses simultaneously using HER2/neu or EpCAM as target receptors

P2860

Q21090521-4F1873CF-E7B2-4320-B03B-D45A8CE9220D Q26748100-FD410804-66C4-42CD-BB08-99C2B52E7BB8 Q26995399-2CBBE150-F7C8-4292-962C-3084D267DA0E Q27315979-62A1CBFB-18B4-4A4E-9005-E8280692B31A Q27318174-642F520F-0B31-401C-ADB7-DF28134ACA52 Q27653157-4E9AF0DC-94CC-4EA5-A7C5-054B4FAB7C01 Q27656822-0AE019BA-87EC-4E2E-B58A-7A4878B0B252 Q27670954-3EEB6A4A-E8B9-42AE-BB00-E75A88D90234 Q27676519-634BFBA5-8152-4D83-BA27-A5552680B5DD Q27677469-84B8A331-FC3A-47FF-87AA-672D521AE67E Q28083126-CDFB9B52-5DB2-41A1-B2F0-795F70834411 Q28272997-2B6E2A23-04D8-49A4-ABC1-0ABC015F613D Q28283011-DA6BD649-4223-4CA8-875B-FFDF7152DEE7 Q28541561-3D521136-58BC-4A58-8157-038FD3C38949 Q28550176-8F899E4A-39CC-4BDD-AA69-8AA6466BBA42 Q28731927-7E282BC4-2F35-4134-8DC2-69A5100BEB96 Q33562012-B0674C0A-8540-40FF-B598-461B552A68B4 Q33597942-184E395D-9C1A-411A-8837-69160E9E6935 Q33732694-AE8188C4-FD66-49CD-88C4-75CFE789A4C3 Q33740415-AC61EE58-C671-43BC-8F95-A02FB77B0315 Q33788445-8141F0AF-E28C-47CB-8842-962343963055 Q33835328-58CF9D35-35A3-4E80-B143-7A465B6F8E67 Q33879313-C7D751E8-1905-443C-9FBA-127D55953ACB Q34163977-751851B3-D32B-4F29-9AA4-3E842055ADE0 Q34415658-F894BB54-8D30-432D-ADDE-54725CB9905E Q34634742-AAED4A8F-1E76-42DD-931C-3FCAA3226086 Q34692067-08ED4D2A-61CB-4BD8-8AC3-BB4495E85D13 Q34698762-C8F524A2-B2C4-411E-B681-29D66F9F543B Q34757199-F097C8AC-87FE-4615-848E-4760A069954F Q35043734-2E46AB5E-CCCD-4AC1-98F0-F0FC17E2A56B Q35201628-2AF9520C-0661-4CE9-8815-F24FD57034A2 Q35262088-E48ED457-2D61-43A4-89AA-45054D4D0CF0 Q35799445-19B07B8D-8ED0-46CE-B772-78C714D29EB7 Q35842099-5A30691A-C071-4B7B-BCBE-18E62F94C4A3 Q36047074-00F17367-0F91-4E66-BFF0-EC5C51032B31 Q36200871-30BBC0CC-6787-477C-94AC-43598A50D423 Q36370414-5492376C-CC9B-485A-9D54-A62E1A833082 Q36406261-924E2576-D25B-4693-B6AF-FCFA78603421 Q36519000-DE63EE80-7611-4B01-9632-299253A7188D Q36777139-6B173F4F-C5D7-43F0-A201-09D8907CE8E1

P2860

A designed ankyrin repeat protein evolved to picomolar affinity to Her2

http://www.wikidata.org/entity/Q27644627

description

2007 nî lūn-bûn

@nan

2007 թուականի Յունիսին հրատարակուած գիտական յօդուած

@hyw

2007 թվականի հունիսին հրատարակված գիտական հոդված

@hy

2007年の論文

@ja

2007年論文

@yue

2007年論文

@zh-hant

2007年論文

@zh-hk

2007年論文

@zh-mo

2007年論文

@zh-tw

2007年论文

@wuu

name

A designed ankyrin repeat protein evolved to picomolar affinity to Her2

@ast

A designed ankyrin repeat protein evolved to picomolar affinity to Her2

@en

A designed ankyrin repeat protein evolved to picomolar affinity to Her2

@nl

type

label

A designed ankyrin repeat protein evolved to picomolar affinity to Her2

@ast

A designed ankyrin repeat protein evolved to picomolar affinity to Her2

@en

A designed ankyrin repeat protein evolved to picomolar affinity to Her2

@nl

prefLabel

A designed ankyrin repeat protein evolved to picomolar affinity to Her2

@ast

A designed ankyrin repeat protein evolved to picomolar affinity to Her2

@en

A designed ankyrin repeat protein evolved to picomolar affinity to Her2

@nl

P1433

Q27644627-302B9E1B-AF13-4B86-AC78-A1989E423182

P1476

Q27644627-0FA1B988-184B-496C-A3BB-C90041857203

P2093

Q27644627-515DFC39-A394-4DDF-868A-EA6096AC735D

Q27644627-75285CD9-703E-429E-A5C2-4D1A64B9B986

Q27644627-A4E8B722-A557-40BA-85A8-F609366600CD

Q27644627-BF405587-F247-43BC-A16E-FC25AC042AB4

Q27644627-C3A203EC-1EBA-45BB-8493-213942D78B99

Q27644627-D67BA707-A9BE-4E10-828D-724FBAF89750

P304

Q27644627-CAF9D70D-7E75-4417-8F61-E0AFEE4F1BF3

P31

Q27644627-A876096F-4235-41E3-86DF-BD67EA1B4020

P3181

Q27644627-8690C7B4-633A-4807-A824-38CB6D260899

P356

Q27644627-83D03330-3940-4ABC-AE1D-0AA64D47CDA8

P407

Q27644627-5A8F1BCB-BBF3-4A48-9AFA-591F41DA0E2E

P433

Q27644627-CB24C014-5F5C-4D7E-992E-42BD44570F58

P478

Q27644627-561CF195-92B6-4F6A-997E-29DE10032C85

P50

Q27644627-0E2DCE75-AF79-4AD2-ADA5-8FC04AD59A81

Q27644627-2EC4A8CE-D208-461B-8C25-AD8100DA29EE

Q27644627-4FC02E59-841C-4446-9ECF-02949848D10B

Q27644627-8E5B3873-EC55-47EB-A82A-7581DEF177FE

P577

Q27644627-20FBA8CF-FF1F-4E43-BD58-8971A9404E3C

P5875

Q27644627-367AE730-FBD2-4B36-ABB1-3C8D1C15D60A

P698

Q27644627-9D253B56-028E-4CAC-81D2-5FC1E3F0C4BB

P921

Q27644627-8E93646F-DF46-4438-BF21-84F1AE744E0D

P3181

P356

J.JMB.2007.03.028

P1433

Journal of Molecular Biology

P1476

A designed ankyrin repeat protein evolved to picomolar affinity to Her2

@en

P2093

Christian Zahnd

http://www.w3.org/2001/XMLSchema#string

Colin W Ward

http://www.w3.org/2001/XMLSchema#string

Daniel Steiner

http://www.w3.org/2001/XMLSchema#string

Frédéric Pecorari

http://www.w3.org/2001/XMLSchema#string

Neil M McKern

http://www.w3.org/2001/XMLSchema#string

Thomas O Joos

http://www.w3.org/2001/XMLSchema#string

P304

1015-28

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P3181

227443

http://www.w3.org/2001/XMLSchema#string

P356

10.1016/J.JMB.2007.03.028

http://www.w3.org/2001/XMLSchema#string

P407

P433

4

http://www.w3.org/2001/XMLSchema#string

P478

369

http://www.w3.org/2001/XMLSchema#string

P50

Andreas Plückthun

Michael C Lawrence

P577

2007-06-15T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

6364236

http://www.w3.org/2001/XMLSchema#string

P698

17466328

http://www.w3.org/2001/XMLSchema#string

P921