Inhibition of caspase-2 by a designed ankyrin repeat protein: specificity, structure, and inhibition mechanism
about
CD4-specific designed ankyrin repeat proteins are novel potent HIV entry inhibitors with unique characteristicsDeep sequencing in library selection projects: what insight does it bring?Conformational change-induced repeat domain expansion regulates Rap phosphatase quorum-sensing signal receptorsToward chaperone-assisted crystallography: Protein engineering enhancement of crystal packing and X-ray phasing capabilities of a camelid single-domain antibody (VHH) scaffoldCrystal Structure and Function of a DARPin Neutralizing Inhibitor of Lactococcal Phage TP901-1: COMPARISON OF DARPin AND CAMELID VHH BINDING MODEA Class of Allosteric Caspase Inhibitors Identified by High-Throughput ScreeningStructural and functional analysis of phosphorylation-specific binders of the kinase ERK from designed ankyrin repeat protein librariesDesign, construction, and characterization of a second-generation DARPin library with reduced hydrophobicityAdhiron: a stable and versatile peptide display scaffold for molecular recognition applicationsCombined inhibition of caspase 3 and caspase 7 by two highly selective DARPins slows down cellular demiseTunable allosteric library of caspase-3 identifies coupling between conserved water molecules and conformational selectionEngineering of recombinant crystallization chaperonesSystematic evaluation of apoptotic pathway gene polymorphisms and lung cancer riskAmyloid-β peptide-specific DARPins as a novel class of potential therapeutics for Alzheimer diseaseCaspase-2 promotes cytoskeleton protein degradation during apoptotic cell death.Cell death by SecTRAPs: thioredoxin reductase as a prooxidant killer of cellsTwo-state selection of conformation-specific antibodiesThe importance of being tyrosine: lessons in molecular recognition from minimalist synthetic binding proteins.Selection and characterization of DARPins specific for the neurotensin receptor 1Her2-specific multivalent adapters confer designed tropism to adenovirus for gene targetingAntiviral activity of recombinant ankyrin targeted to the capsid domain of HIV-1 Gag polyprotein.Emerging principles in protease-based drug discovery.Structural insights for engineering binding proteins based on non-antibody scaffoldsProtein interference applications in cellular and developmental biology using DARPins that recognize GFP and mCherry.Crystal structure of an antiviral ankyrin targeting the HIV-1 capsid and molecular modeling of the ankyrin-capsid complex.A hot-spot motif characterizes the interface between a designed ankyrin-repeat protein and its target ligand.Small Molecule Active Site Directed Tools for Studying Human CaspasesDelivery of antibody mimics into mammalian cells via anthrax toxin protective antigenRepeat-protein folding: new insights into origins of cooperativity, stability, and topology.Folding landscapes of ankyrin repeat proteins: experiments meet theory.Ligand binding by repeat proteins: natural and designed.The role of caspase-2 in stress-induced apoptosis.Mechanisms of macromolecular protease inhibitorsAntibody fragments as tools in crystallography.Affinity proteomics: the role of specific binding reagents in human proteome analysis.Potential applications of designed ankyrin repeat proteins in diagnostics and therapeutics.Vaccinia virus encodes a novel inhibitor of apoptosis that associates with the apoptosome.Nanometer propagation of millisecond motions in V-type allostery.Non-invasive in vivo imaging of tumour-associated cathepsin B by a highly selective inhibitory DARPin.Functional dynamics of the folded ankyrin repeats of I kappa B alpha revealed by nuclear magnetic resonance
P2860
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P2860
Inhibition of caspase-2 by a designed ankyrin repeat protein: specificity, structure, and inhibition mechanism
description
2007 nî lūn-bûn
@nan
2007 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Inhibition of caspase-2 by a d ...... ture, and inhibition mechanism
@ast
Inhibition of caspase-2 by a d ...... ture, and inhibition mechanism
@en
Inhibition of caspase-2 by a d ...... ture, and inhibition mechanism
@nl
type
label
Inhibition of caspase-2 by a d ...... ture, and inhibition mechanism
@ast
Inhibition of caspase-2 by a d ...... ture, and inhibition mechanism
@en
Inhibition of caspase-2 by a d ...... ture, and inhibition mechanism
@nl
prefLabel
Inhibition of caspase-2 by a d ...... ture, and inhibition mechanism
@ast
Inhibition of caspase-2 by a d ...... ture, and inhibition mechanism
@en
Inhibition of caspase-2 by a d ...... ture, and inhibition mechanism
@nl
P2093
P50
P1433
P1476
Inhibition of caspase-2 by a d ...... ture, and inhibition mechanism
@en
P2093
Andreas Schweizer
Christophe Briand
Eva Prenosil
H Kaspar Binz
Markus G Grütter
Maya Gulotti-Georgieva
Patrick Amstutz
P304
P356
10.1016/J.STR.2007.03.014
P577
2007-05-01T00:00:00Z