Crystal structures of human pantothenate kinases. Insights into allosteric regulation and mutations linked to a neurodegeneration disorder
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Induction of Neuron-Specific Degradation of Coenzyme A Models Pantothenate Kinase-Associated Neurodegeneration by Reducing Motor Coordination in MiceConserved structural elements in the V3 crown of HIV-1 gp120Modulation of Pantothenate Kinase 3 Activity by Small Molecules that Interact with the Substrate/Allosteric Regulatory DomainClinical and genetic delineation of neurodegeneration with brain iron accumulationThe role of UPF0157 in the folding of M. tuberculosis dephosphocoenzyme A kinase and the regulation of the latter by CTPGermline deletion of pantothenate kinases 1 and 2 reveals the key roles for CoA in postnatal metabolismCompartmentalization of mammalian pantothenate kinasesPantothenate kinase from the thermoacidophilic archaeon Picrophilus torridus.Biophysical characterization of recombinant proteins: a key to higher structural genomics successA variation in PANK2 gene is causing Pantothenate kinase-associated Neurodegeneration in a family from Jammu and Kashmir - IndiaPantoate kinase and phosphopantothenate synthetase, two novel enzymes necessary for CoA biosynthesis in the Archaea.A high-throughput screen reveals new small-molecule activators and inhibitors of pantothenate kinases.Acanthocytosis and the c.680 A>G Mutation in the PANK2 Gene: A Study Enrolling a Cohort of PKAN Patients from the Dominican Republic.Review: Insights into molecular mechanisms of disease in neurodegeneration with brain iron accumulation: unifying theories.The type III pantothenate kinase encoded by coaX is essential for growth of Bacillus anthracisEffects of non-catalytic, distal amino acid residues on activity of E. coli DinB (DNA polymerase IV).A survey of proteins encoded by non-synonymous single nucleotide polymorphisms reveals a significant fraction with altered stability and activity.iPSC-derived neuronal models of PANK2-associated neurodegeneration reveal mitochondrial dysfunction contributing to early diseaseCrystal Structures of Type-II Inositol Polyphosphate 5-Phosphatase INPP5B with Synthetic Inositol Polyphosphate Surrogates Reveal New Mechanistic Insights for the Inositol 5-Phosphatase Family.Exploring Missense Mutations in Tyrosine Kinases Implicated with Neurodegeneration.Excess coenzyme A reduces skeletal muscle performance and strength in mice overexpressing human PANK2.Allosteric Regulation of Mammalian Pantothenate Kinase.Pantothenate kinase-associated neurodegeneration: insights from a Drosophila model.A distinct metabolic signature of human colorectal cancer with prognostic potential.Application of high-throughput isothermal denaturation to assess protein stability and screen for ligands.Characterization and validation of Entamoeba histolytica pantothenate kinase as a novel anti-amebic drug target.Phenotypes and genotypes of patients with pantothenate kinase-associated neurodegeneration in Asian and Caucasian populations: 2 cases and literature review.A therapeutic approach to pantothenate kinase associated neurodegeneration
P2860
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P2860
Crystal structures of human pantothenate kinases. Insights into allosteric regulation and mutations linked to a neurodegeneration disorder
description
2007 nî lūn-bûn
@nan
2007 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Crystal structures of human pa ...... o a neurodegeneration disorder
@ast
Crystal structures of human pa ...... o a neurodegeneration disorder
@en
Crystal structures of human pa ...... o a neurodegeneration disorder
@nl
type
label
Crystal structures of human pa ...... o a neurodegeneration disorder
@ast
Crystal structures of human pa ...... o a neurodegeneration disorder
@en
Crystal structures of human pa ...... o a neurodegeneration disorder
@nl
prefLabel
Crystal structures of human pa ...... o a neurodegeneration disorder
@ast
Crystal structures of human pa ...... o a neurodegeneration disorder
@en
Crystal structures of human pa ...... o a neurodegeneration disorder
@nl
P2093
P2860
P921
P356
P1476
Crystal structures of human pa ...... o a neurodegeneration disorder
@en
P2093
Bum Soo Hong
Charles O Rock
Hee-Won Park
Roberta Leonardi
Suzanne Jackowski
Wael M Rabeh
Yong-Mei Zhang
P2860
P304
P356
10.1074/JBC.M701915200
P407
P577
2007-09-21T00:00:00Z