Structure of the Antiviral Assembly Inhibitor CAP-1 Complex with the HIV-1 CA Protein - Test2 - elhamkhani - TriplyDB

Structure of the Antiviral Assembly Inhibitor CAP-1 Complex with the HIV-1 CA Protein

Structure of the Antiviral Assembly Inhibitor CAP-1 Complex with the HIV-1 CA Protein

http://www.wikidata.org/entity/Q27647971

about

HIV type 1 Gag as a target for antiviral therapy Virus maturation as a new HIV-1 therapeutic target The choreography of HIV-1 proteolytic processing and virion assembly Focus on flaviviruses: current and future drug targets Solution Structure of a Hydrocarbon Stapled Peptide Inhibitor in Complex with Monomeric C-terminal Domain of HIV-1 Capsid X-ray structures of the hexameric building block of the HIV capsid.Structure of the HIV-1 Full-Length Capsid Protein in a Conformationally Trapped Unassembled State Induced by Small-Molecule Binding HIV Capsid is a Tractable Target for Small Molecule Therapeutic Intervention CPSF6 Defines a Conserved Capsid Interface that Modulates HIV-1 Replication Structure of a Monomeric Mutant of the HIV-1 Capsid Protein Structural Characterization of H-1 Parvovirus: Comparison of Infectious Virions to Empty Capsids Distinct Effects of Two HIV-1 Capsid Assembly Inhibitor Families That Bind the Same Site within the N-Terminal Domain of the Viral CA Protein Discovery of Novel Small-Molecule HIV-1 Replication Inhibitors That Stabilize Capsid Complexes Structure and Dynamics of Full-Length HIV-1 Capsid Protein in Solution Protein structural ensembles are revealed by redefining X-ray electron density noise Cryo-electron microscopy of tubular arrays of HIV-1 Gag resolves structures essential for immature virus assembly Monitoring binding of HIV-1 capsid assembly inhibitors using (19)F ligand-and (15)N protein-based NMR and X-ray crystallography: early hit validation of a benzodiazepine series Rationally designed interfacial peptides are efficient in vitro inhibitors of HIV-1 capsid assembly with antiviral activity STRUCTURAL VIROLOGY. X-ray crystal structures of native HIV-1 capsid protein reveal conformational variability.The structural biology of HIV assembly.Mechanism of action of cyclophilin a explored by metadynamics simulations.The capsid protein of human immunodeficiency virus: designing inhibitors of capsid assembly.A simple fluorescence based assay for quantification of human immunodeficiency virus particle release Role of protein interactions in defining HIV-1 viral capsid shape and stability: a coarse-grained analysis.Novel approaches to inhibiting HIV-1 replication.Virtual screening based identification of novel small-molecule inhibitors targeted to the HIV-1 capsid.Anti-HIV-1 therapeutics: from FDA-approved drugs to hypothetical future targets Structural and dynamical characterization of tubular HIV-1 capsid protein assemblies by solid state nuclear magnetic resonance and electron microscopy Novel postentry inhibitor of human immunodeficiency virus type 1 replication screened by yeast membrane-associated two-hybrid system.Recognition of the HIV capsid by the TRIM5α restriction factor is mediated by a subset of pre-existing conformations of the TRIM5α SPRY domain.MxB binds to the HIV-1 core and prevents the uncoating process of HIV-1 Biophysical characterization of the feline immunodeficiency virus p24 capsid protein conformation and in vitro capsid assembly.A sensitive assay using a native protein substrate for screening HIV-1 maturation inhibitors targeting the protease cleavage site between the matrix and capsid Second-site compensatory mutations of HIV-1 capsid mutations.Crystal structure of an antiviral ankyrin targeting the HIV-1 capsid and molecular modeling of the ankyrin-capsid complex.HIV-1 Gag as an Antiviral Target: Development of Assembly and Maturation Inhibitors.Identification of a small molecule HIV-1 inhibitor that targets the capsid hexamer.Early stages of the HIV-1 capsid protein lattice formation.The structural biology of HIV-1: mechanistic and therapeutic insights HIV-1 Capsid Inhibitors as Antiretroviral Agents

P2860

Q24614498-1C83F55B-A502-4B2F-B939-D25C5F87800F Q24642446-92ECF57E-631C-4BF0-ACE5-498BB27909F5 Q27009643-24E2B12A-B604-4EDC-B134-40498F4D6EE8 Q27490926-58BAE78F-9BDF-43FD-85E6-04003FCB36F7 Q27650342-BB759705-7F05-4C67-A459-EC4EDA48A3E3 Q27655910-8BE7C3F7-3E8C-4AA4-BF65-0299F3457689 Q27666307-19B79DE3-732A-4F0D-8388-7B09E1A18B1E Q27666355-8E3B6ED1-7D43-4B86-A9C9-DE5C239D8C68 Q27672646-622373D7-5BCF-490C-BB3B-5F5547E6615E Q27675009-7B96F26F-F587-4908-A510-64488C728F67 Q27676651-36CA1D76-3910-4425-849A-84BA7A8E89B2 Q27678471-82252556-944D-496A-BD59-BDD26D41B22E Q27678859-9DE122FB-0E0C-4D37-9179-9276A4C0B3D0 Q27680056-55C60F7A-D8E7-4DE6-A538-7B2DE7CC15EE Q27681046-37EEE312-CBEB-46AB-AF7F-8236A008E967 Q27683857-96A4EFDF-E6A1-4021-912A-BBE847BB3DA8 Q27683977-452A5E85-E766-4339-9DE6-33054339DC2E Q28476840-DE7AADFE-163C-48E8-9FA1-C943E352543C Q30279235-4D620C75-0FFF-47E5-B555-D503F7D68630 Q30437103-E6F5C33E-BA19-4A04-9E2E-91F6A8A83B1E Q33417618-D5718642-0F9B-4AAA-8ACC-B926CAB30430 Q33510254-263F96A6-2CEF-4469-A30D-A036078882A8 Q33560406-F3A85AC0-84FF-407B-8146-A53D663575C0 Q33568300-F0075C24-4C0D-4F72-A588-A8BED3BF2B56 Q33624690-41D3DBC8-27A7-48DA-B378-872A440184D8 Q33774977-A0DB85B5-5F7A-4B6B-BC39-D5130397D008 Q33819240-0310C0F1-1D30-4ABB-B2A7-43280854AE89 Q33839020-EEDD283F-5826-4EDA-AC90-D2D344AC63E5 Q33957533-656AF991-FB59-43AD-9CEC-EE22FD0C2E20 Q33989616-D4BD7504-9AF3-44A3-999E-40D7C721FB7E Q34091405-DD493D54-6490-4BD1-B274-AFA0DF164FC2 Q34606804-C069FD41-012E-495C-BE9F-FC5851DD4B86 Q34771244-C1160E10-28A8-45DA-9710-61820F88F400 Q35076692-2C975882-80F6-4654-B0D1-433039AE16B9 Q35201628-EA2175A4-78F7-444D-972D-1DD8ABBF6395 Q35761626-748A5711-101D-415D-8315-B090B7612028 Q35889216-3F980680-5419-47EA-B0D7-7864FE76511F Q36330057-B7BD7CC1-2E61-45BF-B8EB-47ABAC81E61C Q36656440-C4C949DD-B1DF-40AF-AFD8-B7FD29293E79 Q36672006-4740B78D-F6C7-43C1-A8A5-4B5FDA975378

P2860

Structure of the Antiviral Assembly Inhibitor CAP-1 Complex with the HIV-1 CA Protein

http://www.wikidata.org/entity/Q27647971

description

2007 nî lūn-bûn

@nan

2007 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2007 թվականի հոտեմբերին հրատարակված գիտական հոդված

@hy

2007年の論文

@ja

2007年論文

@yue

2007年論文

@zh-hant

2007年論文

@zh-hk

2007年論文

@zh-mo

2007年論文

@zh-tw

2007年论文

@wuu

name

Structure of the Antiviral Assembly Inhibitor CAP-1 Complex with the HIV-1 CA Protein

@ast

Structure of the Antiviral Assembly Inhibitor CAP-1 Complex with the HIV-1 CA Protein

@en

Structure of the Antiviral Assembly Inhibitor CAP-1 Complex with the HIV-1 CA Protein

@nl

type

label

Structure of the Antiviral Assembly Inhibitor CAP-1 Complex with the HIV-1 CA Protein

@ast

Structure of the Antiviral Assembly Inhibitor CAP-1 Complex with the HIV-1 CA Protein

@en

Structure of the Antiviral Assembly Inhibitor CAP-1 Complex with the HIV-1 CA Protein

@nl

prefLabel

Structure of the Antiviral Assembly Inhibitor CAP-1 Complex with the HIV-1 CA Protein

@ast

Structure of the Antiviral Assembly Inhibitor CAP-1 Complex with the HIV-1 CA Protein

@en

Structure of the Antiviral Assembly Inhibitor CAP-1 Complex with the HIV-1 CA Protein

@nl

P1433

Q27647971-84267800-F8F7-4B35-A11D-590D4FD4DF02

P1476

Q27647971-E2976A3C-B436-489F-B7F8-0A787307A170

P2093

Q27647971-4108844F-0354-420D-8C47-5035BCC2F350

Q27647971-4392C900-2D82-422D-B3D7-9378E2C7DA30

Q27647971-48919D8F-35E7-41FB-933D-1D3A4D207814

Q27647971-6C3A3564-07DF-4011-B674-6C58AEF21AA4

Q27647971-6F4B514C-D7D0-452F-9216-4E9140BA47C8

Q27647971-BA88175F-1DF7-4F0D-A4DD-A9758516A685

Q27647971-C1BC94B0-B1E8-47C1-8251-089071333ADF

Q27647971-D24A9FE4-9D4A-47DF-9EA2-DF4C3A599723

Q27647971-E45F75D3-FB20-44BC-A2C5-CBA231A0D7A9

P2860

Q27647971-0016F75D-050A-4837-B1C0-5E67BB1988E0

Q27647971-04BD7C3A-D96A-41AA-9921-F38F6F938D72

Q27647971-0C886F14-3F27-44B3-A274-B67116FED2A1

Q27647971-13784D1D-428C-4B20-AB24-8FDD50D4CC18

Q27647971-14459610-8F5E-4496-B793-71C78637C5AC

Q27647971-14CF2264-9C73-42BB-8485-38352F6C22A3

Q27647971-1DCA3A4E-994D-4C53-B38C-780DC1FFA7B5

Q27647971-201BDC81-02EC-490D-9A9B-708B09D8754D

Q27647971-217643F5-FFBF-43FC-BCE9-59B21B2F17E2

Q27647971-28F19133-B84B-41C9-9563-1F0F033CCE0C

P304

Q27647971-10FB5FE4-20F7-4D33-A9A7-408DD2267C08

P31

Q27647971-826BFCAF-6B03-4E25-AA67-D5B989A29D63

P3181

Q27647971-B23D0D54-4F6B-40AA-B171-7B170CEDC76E

P356

Q27647971-D8953A51-3756-46B4-B8FA-89790DD66C69

P407

Q27647971-4C495AFD-B7DA-45DE-B6E3-D5B75636A5B4

P433

Q27647971-D867F0EB-30B1-4530-A59F-BF55637CEDDD

P478

Q27647971-FC9660E5-9E6E-4050-BDCD-A21AC43FBDB9

P577

Q27647971-D5AF437A-DD1D-482C-B797-20A50BBD5820

P5875

Q27647971-B911CF7C-5BE4-40C3-A544-318997C2C95F

P698

Q27647971-9861D5A0-CEEB-4471-B27E-584DD2C76EB0

P932

Q27647971-32C8002B-57BB-4F0E-AC51-F88E4DD1A7EF

P3181

P356

J.JMB.2007.07.070

P1433

Journal of Molecular Biology

P1476

Structure of the Antiviral Assembly Inhibitor CAP-1 Complex with the HIV-1 CA Protein

@en

P2093

Brian N Kelly

http://www.w3.org/2001/XMLSchema#string

Bruce R Howard

http://www.w3.org/2001/XMLSchema#string

Christopher P Hill

http://www.w3.org/2001/XMLSchema#string

Chun Tang

http://www.w3.org/2001/XMLSchema#string

Howard Robinson

http://www.w3.org/2001/XMLSchema#string

Isaac Kinde

http://www.w3.org/2001/XMLSchema#string

Michael F Summers

http://www.w3.org/2001/XMLSchema#string

Sampson Kyere

http://www.w3.org/2001/XMLSchema#string

Wesley I Sundquist

http://www.w3.org/2001/XMLSchema#string

P2860

Structural insights into the catalytic mechanism of cyclophilin A

Mammalian SCAN domain dimer is a domain-swapped homolog of the HIV capsid C-terminal domain

Structures of the HIV-1 capsid protein dimerization domain at 2.6 A resolution

Domain-swapped dimerization of the HIV-1 capsid C-terminal domain

High resolution structures of HIV-1 RT from four RT-inhibitor complexes

Structure of HIV-1 RT/TIBO R 86183 complex reveals similarity in the binding of diverse nonnucleoside inhibitors

Structure of the carboxyl-terminal dimerization domain of the HIV-1 capsid protein

Coot: model-building tools for molecular graphics

Likelihood-enhanced fast translation functions

The Amber biomolecular simulation programs

P304

355-66

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P3181

2127726

http://www.w3.org/2001/XMLSchema#string

P356

10.1016/J.JMB.2007.07.070

http://www.w3.org/2001/XMLSchema#string

P407

P433

2

http://www.w3.org/2001/XMLSchema#string

P478

373

http://www.w3.org/2001/XMLSchema#string

P577

2007-10-19T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

6013313

http://www.w3.org/2001/XMLSchema#string

P698

17826792

http://www.w3.org/2001/XMLSchema#string

P932

2066180

http://www.w3.org/2001/XMLSchema#string