Three-dimensional Structure of the EphB2 Receptor in Complex with an Antagonistic Peptide Reveals a Novel Mode of Inhibition
about
Eph receptors and ephrin ligands: important players in angiogenesis and tumor angiogenesisTargeting the Eph System with Peptides and Peptide ConjugatesStructural basis of Nipah and Hendra virus attachment to their cell-surface receptor ephrin-B2Crystal Structure and NMR Binding Reveal That Two Small Molecule Antagonists Target the High Affinity Ephrin-binding Channel of the EphA4 ReceptorStructure of the ligand-binding domain of the EphB2 receptor at 2 Å resolutionStructural Characterization of the EphA4-Ephrin-B2 Complex Reveals New Features Enabling Eph-Ephrin Binding PromiscuityEph receptors and ephrins in cancer: bidirectional signalling and beyond.Essential roles of EphB receptors and EphrinB ligands in endothelial cell function and angiogenesis.Protein dynamics at Eph receptor-ligand interfaces as revealed by crystallography, NMR and MD simulations.Unique structure and dynamics of the EphA5 ligand binding domain mediate its binding specificity as revealed by X-ray crystallography, NMR and MD simulationsA disalicylic acid-furanyl derivative inhibits ephrin binding to a subset of Eph receptorsInvestigation of the interactions between the EphB2 receptor and SNEW peptide variants.Distinctive binding of three antagonistic peptides to the ephrin-binding pocket of the EphA4 receptor.Eph receptors in breast cancer: roles in tumor promotion and tumor suppression.Tie2 and Eph receptor tyrosine kinase activation and signaling.Targeting Eph receptors with peptides and small molecules: progress and challenges.Structural studies on Laz, a promiscuous anticancer Neisserial protein.Fluorine-18 radiolabeling and radiopharmacological characterization of a benzodioxolylpyrimidine-based radiotracer targeting the receptor tyrosine kinase EphB4.Small molecules can selectively inhibit ephrin binding to the EphA4 and EphA2 receptorsEphB and Ephrin-B interactions mediate human mesenchymal stem cell suppression of activated T-cells.An efficient bioorthogonal strategy using CuAAC click chemistry for radiofluorinations of SNEW peptides and the role of copper depletion.Preparation of a novel radiotracer targeting the EphB4 receptor via radiofluorination using spiro azetidinium salts as precursor.EphrinB2 signalling modulates the neural differentiation of human dental pulp stem cells.The osteoprogenitor-specific loss of ephrinB1 results in an osteoporotic phenotype affecting the balance between bone formation and resorption
P2860
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P2860
Three-dimensional Structure of the EphB2 Receptor in Complex with an Antagonistic Peptide Reveals a Novel Mode of Inhibition
description
2007 nî lūn-bûn
@nan
2007 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Three-dimensional Structure of ...... als a Novel Mode of Inhibition
@ast
Three-dimensional Structure of ...... als a Novel Mode of Inhibition
@en
Three-dimensional Structure of ...... als a Novel Mode of Inhibition
@nl
type
label
Three-dimensional Structure of ...... als a Novel Mode of Inhibition
@ast
Three-dimensional Structure of ...... als a Novel Mode of Inhibition
@en
Three-dimensional Structure of ...... als a Novel Mode of Inhibition
@nl
prefLabel
Three-dimensional Structure of ...... als a Novel Mode of Inhibition
@ast
Three-dimensional Structure of ...... als a Novel Mode of Inhibition
@en
Three-dimensional Structure of ...... als a Novel Mode of Inhibition
@nl
P2093
P2860
P356
P1476
Three-dimensional Structure of ...... als a Novel Mode of Inhibition
@en
P2093
Alexei Brooun
Elena B Pasquale
George Nicola
Hans Widmer
Jill E Chrencik
Leila K Davis
Michael I Recht
Peter Kuhn
P2860
P304
P356
10.1074/JBC.M706340200
P407
P577
2007-12-14T00:00:00Z