Structural basis for activation of the autoinhibitory C-terminal kinase domain of p90 RSK2 - Test2 - elhamkhani - TriplyDB

Structural basis for activation of the autoinhibitory C-terminal kinase domain of p90 RSK2

Structural basis for activation of the autoinhibitory C-terminal kinase domain of p90 RSK2

http://www.wikidata.org/entity/Q27649349

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Specificity of linear motifs that bind to a common mitogen-activated protein kinase docking groove Structural Diversity of the Active N-Terminal Kinase Domain of p90 Ribosomal S6 Kinase 2 The Crystal Structure of the Active Form of the C-Terminal Kinase Domain of Mitogen- and Stress-Activated Protein Kinase 1 ATPase-dependent role of the atypical kinase Rio2 on the evolving pre-40S ribosomal subunit Reversible targeting of noncatalytic cysteines with chemically tuned electrophiles Structural basis for the autoinhibition of the C-terminal kinase domain of human RSK1 Prediction of molecular targets of cancer preventing flavonoid compounds using computational methods Computational and Biochemical Discovery of RSK2 as a Novel Target for Epigallocatechin Gallate (EGCG)The unusual mechanism of inhibition of the p90 ribosomal S6 kinase (RSK) by flavonol rhamnosides.RSK2 Binding Models Delineate Key Features for Activity Structural assembly of the signaling competent ERK2-RSK1 heterodimeric protein kinase complex.Structural Basis of Ribosomal S6 Kinase 1 (RSK1) Inhibition by S100B Protein: MODULATION OF THE EXTRACELLULAR SIGNAL-REGULATED KINASE (ERK) SIGNALING CASCADE IN A CALCIUM-DEPENDENT WAY.Signal transduction and molecular targets of selected flavonoids.A Rising Cancer Prevention Target of RSK2 in Human Skin Cancer.Multiple myeloma phosphotyrosine proteomic profile associated with FGFR3 expression, ligand activation, and drug inhibition.Regulation of protein kinase A activity by p90 ribosomal S6 kinase 1.Fibroblast growth factor receptor 3 associates with and tyrosine phosphorylates p90 RSK2, leading to RSK2 activation that mediates hematopoietic transformation.PDB-scale analysis of known and putative ligand-binding sites with structural sketches.De-RSKing ERK - regulation of ERK1/2-RSK dissociation by phosphorylation within a disordered motif.Dynamic control of RSK complexes by phosphoswitch-based regulation.Functional Basis and Biophysical Approaches to Characterize the C-Terminal Domain of Human-Ribosomal S6 Kinases-3.RSK2 is required for TRAF6 phosphorylation-mediated colon inflammation.Dimethyl fumarate is an allosteric covalent inhibitor of the p90 ribosomal S6 kinases Carnosol suppresses patient-derived gastric tumor growth by targeting RSK2

P2860

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P2860

Structural basis for activation of the autoinhibitory C-terminal kinase domain of p90 RSK2

http://www.wikidata.org/entity/Q27649349

description

2008 nî lūn-bûn

@nan

2008 թուականի Յունուարին հրատարակուած գիտական յօդուած

@hyw

2008 թվականի հունվարին հրատարակված գիտական հոդված

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2008年の論文

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2008年論文

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2008年論文

@zh-hant

2008年論文

@zh-hk

2008年論文

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2008年論文

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2008年论文

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name

Structural basis for activatio ...... inal kinase domain of p90 RSK2

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Structural basis for activatio ...... inal kinase domain of p90 RSK2

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Structural basis for activatio ...... inal kinase domain of p90 RSK2

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type

label

Structural basis for activatio ...... inal kinase domain of p90 RSK2

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Structural basis for activatio ...... inal kinase domain of p90 RSK2

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Structural basis for activatio ...... inal kinase domain of p90 RSK2

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prefLabel

Structural basis for activatio ...... inal kinase domain of p90 RSK2

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Structural basis for activatio ...... inal kinase domain of p90 RSK2

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Structural basis for activatio ...... inal kinase domain of p90 RSK2

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P1433

Nature Structural & Molecular Biology

P1476

Structural basis for activatio ...... inal kinase domain of p90 RSK2

@en

P2093

Ann Bode

http://www.w3.org/2001/XMLSchema#string

Ke Yao

http://www.w3.org/2001/XMLSchema#string

Margarita Malakhova

http://www.w3.org/2001/XMLSchema#string

Sung-Young Lee

http://www.w3.org/2001/XMLSchema#string

Yong-Yeon Cho

http://www.w3.org/2001/XMLSchema#string

Zigang Dong

http://www.w3.org/2001/XMLSchema#string

P2860

Requirement of Rsk-2 for epidermal growth factor-activated phosphorylation of histone H3

Phosphorylation of p90 ribosomal S6 kinase (RSK) regulates extracellular signal-regulated kinase docking and RSK activity

The conformational plasticity of protein kinases

Identification of regulatory phosphorylation sites in mitogen-activated protein kinase (MAPK)-activated protein kinase-1a/p90rsk that are inducible by MAPK

Coupling of the RAS-MAPK pathway to gene activation by RSK2, a growth factor-regulated CREB kinase

Identification of an extracellular signal-regulated kinase (ERK) docking site in ribosomal S6 kinase, a sequence critical for activation by ERK in vivo

Characterization of the p90 ribosomal S6 kinase 2 carboxyl-terminal domain as a protein kinase

Structure of a peptide inhibitor bound to the catalytic subunit of cyclic adenosine monophosphate-dependent protein kinase

Generation of constitutively active p90 ribosomal S6 kinase in vivo. Implications for the mitogen-activated protein kinase-activated protein kinase family.

Insulin-stimulated MAP-2 kinase phosphorylates and activates ribosomal protein S6 kinase II.

P2888

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112-3

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scholarly article

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10.1038/NSMB1347

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1

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15

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Valentina Tereshko

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2008-01-01T00:00:00Z

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5765026

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1032827888

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18084304

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P921

structural biology

P932

2864125

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